A5005951009- Nasal Surgery and Airway Studies
- Head and Neck Surgical Oncology
- Sinusitis and nasal conditions
- Tracheal and airway disorders
- Ear Surgery and Otitis Media
- Congenital Ear and Nasal Anomalies
- Allergic Rhinitis and Sensitization
- Tumors and Oncological Cases
- Oral and Maxillofacial Pathology
- Vestibular and auditory disorders
- Olfactory and Sensory Function Studies
- Hearing, Cochlea, Tinnitus, Genetics
- Surgical Simulation and Training
- Asthma and respiratory diseases
- Cystic Fibrosis Research Advances
- Cleft Lip and Palate Research
- Anatomy and Medical Technology
- Teratomas and Epidermoid Cysts
- Obstructive Sleep Apnea Research
- Head and Neck Anomalies
- Airway Management and Intubation Techniques
- Neuroscience of respiration and sleep
- Foreign Body Medical Cases
- Respiratory and Cough-Related Research
- Esophageal and GI Pathology
University of North Carolina at Chapel Hill
2014-2024
Radford University
2023
American Academy of Otolaryngology — Head and Neck Surgery
2020-2022
University of North Carolina Hospitals
2016
Communities In Schools of Orange County
1999-2006
University of Baltimore
2003
Chapel Hill Carrboro City Schools
1996-1997
Hypothesis: A simulated, multicolor, multi-material temporal bone model can be created using 3-dimensional (3D) printing that will prove both safe and beneficial in training for actual surgical cases. Background: As the process of additive manufacturing, or 3D printing, has become more practical affordable, a number applications technology field Otolaryngology–Head Neck Surgery have been considered. One area promise is simulation. Methods: Three-dimensional representations human bones were...
Objectives/Hypothesis Augmented reality (AR) allows for the addition of transparent virtual images and video to one's view a physical environment. Our objective was develop head‐worn, AR system accurate, intraoperative localization pathology normal anatomic landmarks during open head neck surgery. Study Design Face validity case study. Methods A protocol developed creation three‐dimensional (3D) models based on computed tomography scans. Using HoloLens platform, novel registration tracking...
Objectives/Hypothesis The purpose of this study is to present one the largest case series pediatric transoral robotic surgery (TORS) in upper airway demonstrating a wide range ages and indications. Study Design A retrospective at an academic tertiary referral center from August 2010 September 2014. Methods da Vinci surgical robot (Intuitive Surgical, Inc., Sunnyvale, CA) was used on 16 patients for 18 procedures. variety pathologies reconstructions children with weights were treated. No...
Objective The American Academy of Otolaryngology–Head and Neck Surgery Foundation’s (AAO‐HNSF’s) 3D‐Printed Temporal Bone Working Group was formed with the goal sharing information experience relating to development 3D‐printed temporal bone models. group conducted a multi‐institutional study directly compare several recently developed Study Design Expert opinion survey. Setting laboratory. Methods working convened in 2018. various methods which 3D virtual models had been created printed...
Nitric oxide (NO) production in the respiratory epithelium of upper airways has recently been described. To better delineate role epithelial NO, authors this study attempted to identify cell type responsible for NO rat tracheal and human nasal epithelium. They localized activity through immunohistochemical analysis with an antibody L-citrulline, a marker L-arginine-dependent nitric synthase (NOS) pathway. Using anti-inducible NOS (iNOS) anti-constitutive (cNOS) antibodies, they also specific...
Background: Limited quality of life data exist for pediatric chronic rhinosinusitis (CRS) patients undergoing endoscopic sinus surgery (ESS). Further exploration the following areas will enhance understanding and support clinical decision-making: baseline post-ESS general disease-specific life, parent vs. child report, correlation nasal endoscopy to CT scores. Methodology: A prospective cohort study evaluated CRS age 5-18 ESS. Surveys were completed at two timepoints: (1) pre-ESS (2) 30-90...
Background The etiology of the intense inflammatory response showed by patients with allergic fungal rhinosinusitis (AFRS) remains a mystery. Potential sources this inflammation may include proteases. Protease‐activated receptors (PARs) are components innate immune that modulated proteolytic activity and involved in potentiating T helper 2 (Th2) responses. objective study was to determine whether there is differential expression PARs AFRS compared controls. Methods designed as comparison...
The mechanisms that regulate mucin release in chronic otitis media with effusion, a leading cause of hearing loss children, remain largely unknown. We developed an animal model using Sprague-Dawley rats to determine the factors responsible for production effusion. N-nitro-L-arginine methyl ester (L-NAME), competitive inhibitor nitric oxide synthase, was used investigate role secretion by middle ear epithelium. All underwent eustachian tube obstruction. In first set rats, then injected...
The role of allergy in eustachian tube dysfunction is controversial. In this study, was simulated by exposure to histamine, and function testing performed an experimental rat model.Ventilatory assessed measuring passive opening closing pressures the after challenge with either transtympanic or intranasal histamine. mucociliary clearance time tubotympanum observing dye transport from middle ear nasopharynx histamine control solution.There a statistically significant increase versus addition,...
The greater palatine canal (GPC) local injection is used to limit posterior bleeding during sinus surgery in adults. Given the potential for causing iatrogenic damage intraorbital contents, this procedure not commonly pediatric population. No studies have described anatomic development of GPC facial growth. By using age-stratified radioanatomic analysis, dimensions and clinical implications are patients. An study was performed.High-resolution computed tomography measurements included...
Background: Limited quality of life data exist for pediatric chronic rhinosinusitis (CRS) patients undergoing endoscopic sinus surgery (ESS).Further exploration the following areas will enhance understanding and support clinical decision-making: baseline post-ESS general disease-specific life, parent vs. child report, correlation nasal endoscopy to CT scores. Methodology: A prospective cohort study evaluated CRS age 5-18 ESS.Surveys were completed at two timepoints: (1) pre-ESS (2) 30-90...
Noise-induced hearing loss associated with the workplace has been well described. Far less is known, however, about risks to from recreational sources of noise. We investigated popular sport stock car racing as a potentially significant source noise exposure, and we conducted sound-level survey at National Association for Stock Car Auto Racing (NASCAR) event. Noise levels measured during race ranged 96.5 104 dB(A) 46 meters ( approximately 150 feet) track 99 109 6 20 track. The peak sound...
<h3>Objectives</h3> To characterize the ultrasonographic appearance of laryngeal papillomatosis and to compare ultrasound with direct laryngoscopy bronchoscopy, criterion standard, for airway evaluation. <h3>Design</h3> Prospective, nonrandomized analysis preoperative postoperative images. <h3>Setting</h3> Tertiary, university-based medical center. <h3>Participants</h3> Eight patients (4 females 4 males) recurrent respiratory papillomatosis, a mean age 10.25 years 14 surgical papilloma...
Journal Article Adenosine cardioplegia: reducing reperfusion injury of the ischaemic myocardium? Get access European Cardio-Thoracic Surgery, Volume 5, Issue 10, October 1991, Pages 542–545, https://doi.org/10.1016/1010-7940(91)90108-V Published: 01 1991
OBJECTIVES Develop a model of nasal allergen‐induced Eustachian tube dysfunction (ETD) in rat and investigate the role immune modulatory oligonucleotides (IMOs) prevention ETD. STUDY DESIGN AND SETTING Prospective, randomized study. Brown Norway rats were sensitized to ova albumin (OVA) receive pretreatment with IMOs or phosphate‐buffered saline. All animals challenged intranasally aerosolized OVA. Dynamic measures (ET) function analyzed. RESULTS Animals that OVA‐sensitized IMO‐pre‐treated...