Abstract Objective: Cartilage repair remains a challenging medical issue with lack of effective solutions to date. Synovial chondromatosis (SC) is rare benign tumor caused by synovial metaplasia. A characteristic feature SC the synovium’s spontaneous ability form translucent cartilage nodules. Currently, molecular mechanisms behind formation in vivo are poorly understood. Our study aims investigate chondrogenesis and dynamic changes between cell subpopulations at cellular level using...

Abstract Osteoarthritis (OA) is a condition associated with severe inflammation, cartilage destruction and degeneration of joints. Rhein (Rh) an effective anti-inflammatory drug proven efficacy in in-vitro in-vivo models. pH sensitive Rh NH 4 HCO 3 laden poly (lactic-co-glycolic acid (PLGA) nanoparticles (NPs) (Rh-PLGA-NPs@NH ) are developed for treatment OA. The Rh-PLGA-NPs@NH prepared along Rh-PLGA-NPs as control by double emulsion method. was characterized their size, shape, morphology...

Globally, osteoarthritis (OA) is the most prevalent joint disease and characterized by infiltration of M1 macrophages in synovium, anabolic-catabolic imbalance extracellular matrix (ECM), increased articular shear force overproduction reactive oxygen species (ROS). Disease-modifying OA drugs are not yet available, treatments for focus solely on reducing pain inflammation have limited therapeutic effect. Herein, we developed an injectable self-lubricating poly(N-acryloyl alaninamide) (PNAAA)...

Objective To investigate the outcomes of hip arthroscopy for femoroacetabular impingement (FAI) in patients over age 50 years. Method This is a therapeutic case series study. A total 27 FAI years who met inclusion and exclusion criteria were being followed up at least 2 orthopaedics department our hospital between January 2015 October 2017 recruited prospective analysis on arthroscopy. All underwent unilateral surgery. Of included, there 15 men 12 women, aged 50–74 old (57 ± 6.4 years). The...

Developmental dysplasia of the hip (DDH) is one most common diseases causing pain in adults and an important cause osteoarthritis (OA). Borderline developmental (BDDH) a condition that falls between normal adult DDH. In BDDH, lateral center-edge angle (LCEA) acetabulum usually defined 18° 25° or 20° 25°; however, this definition remains controversial.[1] Freiman SM et al[2] reported prevalence symptomatic BDDH to be as high 12.8%, risk OA individuals with 1.4 2.0 times healthy population....

This study is aimed to delve into the crucial proteins associated with hormonal osteonecrosis of femoral head (ONFH) and its intra-articular lesions through data-independent acquisition (DIA) proteomics bioinformatics analysis.

Background: Acquired immunodeficiency syndrome is a malignant infectious disease caused by the human virus (HIV). HIV gradually destroys body’s immune system and weakens ability to resist diseases. People living with may have higher incidence of coronary heart than people without HIV. Method: A literature retrieval from January 1, 1993 October 2023 based on Web Science Core Collection database. CiteSpace6.2.R4, VOSviewer v1.6.19, Microsoft Excel 2019 were utilized for analyzing following...

Despite transosseous rotator cuff tear repair using sutures is widely accepted for tendon-bone fixation, the fibrocartilaginous enthesis regeneration still hardly achieved with traditional sutures. In present work, degradable magnesium (Mg) alloy wire was applied to suture supraspinatus tendon in a rat acute model Vicryl Plus 4–0 absorbable as control. The shoulder joint humerus-supraspinatus complex specimens were retrieved at 4, 8, and 12 weeks after operation. Mg groups showed better...

Abstract Purpose This retrospective study summarized the clinical, radiographic, and arthroscopic manifestation of synovial chondromatosis (SC) hip, along with post-operative effect to discuss curative management hip SC. Methods Twenty-one patients who underwent surgery from same surgeon for SC were followed up an average 45 months. T-shaped capsulotomy was routinely performed in each case. Visual analog scale, range motion, modified Harris Hip Score, International Outcome Tool score...

Abstract Background This study was performed to compare the clinical efficacies of anterior cruciate ligament (ACL) reconstruction with autologous grafting at different time points. Methods Eighty‐five patients ACL were categorized into two groups: Group A (GA, n = 45), who underwent early‐stage (≤3 weeks) surgery, and B (GB, 40), advanced‐stage (>3 surgery. Perioperative conditions, knee joint functions, activity stability before 6 months postoperatively, changes in quality life (QOL),...

Objectives There is no clear consensus so far on which fixation method most favorable for the tibial tunnel in anterior cruciate ligament reconstruction (ACLR). The purpose of this paper to investigate outcome RigidFix cross pins and explore advantages applied both femoral with hamstring tendon graft reconstruction. Methods This retrospective study included 53 patients (male/female, 45/8) who underwent using autologous tendons between January 2013 December 2017 at our institute. participants...

Objective To determine the effectiveness of hip arthroscopy combined with endoscopic iliotibial band (ITB) release in patients both femoroacetabular impingement (FAI) syndrome and external snapping (ESH). Methods Retrospectively review preoperative minimum 2‐year follow‐up data FAI ESH who underwent ITB during (FAI + group) from January 2014 to December 2018. The same number age‐ gender‐matched without undergoing were enrolled control group group). Patient‐reported outcomes (PROs) including...

Abstract Objective: This study used electronic medical record information and machine learning methods to develop a model predicting the risk of hypertension in HIV/AIDS patients. Method: focused on patients admitted Henan Infectious Disease Hospital China from September 2017 October 2022. The researchers extracted 84 clinical features records. Feature selection was performed using mutual information, Recursive Elimination, Lasso regression, Principal Component Analysis. Five prediction...

The retear rate of rotator cuff (RC) after surgery is high, and rapid functional enthesis regeneration remains a challenge. Whether acellular amniotic membrane (AAM) helps to promote the healing tendon bone which treatment better are both unclear. study aims investigate effect AAM on RC best for repair. Thirty-three Sprague Dawley rats underwent transection repair using microsurgical techniques were randomly divided into suturing only (SRO) group (n = 11), overlaying (AOL) interposition...

Rotator cuff retear after arthroscopy repair is a difficult complication that often due to poor tendon-bone healing. Decellularized amniotic membrane (DAM) has variety of bioactive substances which have great potential enhance However, DAM three layers, the middle basement layer dense and thick. Whether will hinder healing rotator surgical unclear. Our study aims investigate effect on repair. Thirty-three Sprague-Dawley (SD) rats were selected establish unilateral supraspinatus (ST) tear...

Background: Local anesthesia (LA) is widely used in knee arthroscopic surgery but not ankle arthroscopy. Objective: To understand the effectiveness and safety of LA combined with ropivacaine pain control for Study Design: Retrospective cohort. Methods: We retrospectively collected data patients who underwent arthroscopy from April 2012 to 2017. Patients were grouped by method: LA, (LA+R), spinal (SA), SA (SA+R). Intra- postoperative visual analog scale (VAS) scores, complications, doses...

Objective To investigate the methods and outcomes of hip arthroscopy for labrum calcification, to discuss clinical, imaging, intraoperative findings calcification. Methods This is a therapeutic case series study. From January 2015 June 2018, 15 patients who met inclusion exclusion criteria were followed up at least 2 years an analysis on in treatment calcification patients. There eight males seven females, with average age 38.9 ± 8.8 (range, 23–50 years). The visual analog scale (VAS),...

Abstract Purpose ：This retrospective study summarized the clinical, radiographic and arthroscopic manifestation of synovial chondromatosis (SC) hip, along with post-operative effect to discuss curative management hip SC. Methods : 21 patients underwent surgery from same surgeon for SC were followed up an average 45 months. T-shaped capsulotomy was routinely performed in each case. Visual analog scale, range motion, modified Harris Hip score International Outcome Tool collected preoperatively...

The paper presents a high accuracy learning dynamic models system for gaze point mapping based on capturing eye movement from front camera of mobile devices. In the stage detect pupil, we used Haar feature-based cascade classifier real-time detection, and connect region algorithm pupil tracking. mapping, constructed model by coordinate data collected, denoising them density-based cluster algorithm, with mechanism. Finally, leaning were evaluated set experiments, results demonstrated...

According to the literature review, no cyst of hip ligamentum teres has been reported. In this study, a 50-year-old female patient was admitted hospital because sprained left pain with movement restriction for 15 months. The unilateral joint MRI showed teres, which diagnosed as in outpatient department. Thus, hospital. Physical examination that slightly restricted positive FADDIR test and FABER test. Arthroscopic surgical revealed 1.5 cm×1.0 cm at location round ligament then cleared planer...

To investigate and compare the clinical efficacies of remnant-preserving remnant-non-preserving, remnant-non-preserving remnant segment preserving root with anterior cruciate ligament reconstruction.From March 2014 to December 2017, 204 patients (ACL) injuries were treated by single-bundle ACL reconstruction hamstring tendon autograft. According different methods preservation, procedures divided into group (A), (B), (C). There 37 males 39 femalesin A aged from 16 43 years old an average...

Abstract Purpose ：This retrospective study summarized the clinical, radiographic and arthroscopic manifestation of synovial chondromatosis (SC) hip, along with post-operative effect to discuss curative management hip SC. Methods : 21 patients underwent surgery from same surgeon for SC were followed up an average 45 months. T-shaped capsulotomy was routinely performed in each case. Visual analog scale, range motion, modified Harris Hip score International Outcome Tool collected preoperatively...

OBJECTIVE To evaluate early clinical effects of bioabsorbable suture anchors for the treatment Bankart lesion. METHODS Total 23 patients with lesion were treated arthroscopic repair using from January 2010 to June 2017. There 20 males and 3 females, an average age (23.4±3.9) years old (ranged, 19 34 old). Fourteen had injuries on right shoulder joint 9 left side. The mechanism primary dislocation included 17 cases training, 5 sports injury 1 case falling down. mean interval time surgery...