A5048838651- Parasitic infections in humans and animals
- Orthopedic Infections and Treatments
- Infectious Diseases and Tuberculosis
- Orthopaedic implants and arthroplasty
- Medical Imaging and Analysis
- Thyroid Cancer Diagnosis and Treatment
- Healthcare and Venom Research
- Sarcoma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Bone Tissue Engineering Materials
- Spine and Intervertebral Disc Pathology
- Heat shock proteins research
- Osteoarthritis Treatment and Mechanisms
- Mesenchymal stem cell research
- Congenital Anomalies and Fetal Surgery
- Radiomics and Machine Learning in Medical Imaging
- Parasitic Infections and Diagnostics
- Musculoskeletal synovial abnormalities and treatments
- Musculoskeletal pain and rehabilitation
- Parasite Biology and Host Interactions
- Bone health and treatments
- Tendon Structure and Treatment
- Spinal Hematomas and Complications
- Management of metastatic bone disease
- Viral-associated cancers and disorders
Xinjiang Medical University
2015-2025
Sixth Affiliated Hospital of Xinjiang Medical University
2022-2025
Guangzhou Medical University
2012-2024
Jinan University
2020-2024
The First People's Hospital of Shunde
2020-2024
First Affiliated Hospital of Xinjiang Medical University
2012-2023
First Affiliated Hospital of Guangzhou Medical University
2011-2022
The Affiliated Shunde Hospital of Jinan University
2020-2021
First Affiliated Hospital of Jinan University
2020
Liaoning Jianzhu Vocational University
2020
A preliminary report of clinical study revealed that chronic discogenic low back pain could be treated by intradiscal methylene blue (MB) injection. We investigated the effect MB injection for treatment in a randomized placebo-controlled trial. recruited 136 patients who were found potentially eligible after examination and 72 became discography. All had lasting longer than 6 months, with no comorbidity. Thirty-six allocated to 36 placebo treatment. The principal criteria judge effectiveness...
Post-traumatic related limb osteomyelitis (PTRLO) is a complex bone infection. Currently, there are no available microbial data on national scale that can guide appropriate antibiotic selection, and explore the dynamic changes in dominant pathogens over time. This study aimed to conduct comprehensive epidemiological analysis of PTRLO China.The was approved by Institutional Research Board (IRB), 3526 patients were identified from 212 394 traumatic fracture at 21 hospitals between 1 January...
Significance A viral etiology of osteosarcoma was proposed previously but has never been proven by identifying any virus authentically associated with human osteosarcoma. The current study revealed an association KSHV infection in patients Xinjiang subgroups. First, this provides evidence that supports a some osteosarcomas. gene expression profiling showed KSHV-positive represents distinct subtype which is diagnostic, prognostic, and therapeutic significance. Second, KSHV-associated...
Lumbar spinal stenosis (LSS) is an increasingly important issue related to back pain in elderly patients, resulting significant socioeconomic burdens. Postoperative complications and effects are evaluated using the clinical parameter of hospital length stay (LOS). This study aimed develop a machine learning-based tool that can calculate risk prolonged (PLOS) after surgery interpret results. Patients were registered from spine department our hospital. Hospital stays greater than or equal 75th...
Objective: Exosomes are unique bio-nanomaterials possessing significant value and potential for drug delivery systems. However, to date, no bibliometric studies in this field have been reported. Our aim is explore the research hotspots trends of exosome drug-carrying systems across various medical fields through analyses. Methods: Articles reviews related “exosome” “drug delivery” retrieved from Web Science Core Collection. VOSviewer, CiteSpace, Scimago Graphica, Origin 2021 employed...
Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), remains one of the leading causes death among infectious diseases. Enhancing ability anti-tuberculosis drugs to eradicate within host cells a significant challenge. A mannosamine-modified nanoparticle delivery system was developed using poly(lactic-co-glycolic acid) (PLGA) copolymers enhance targeted rifapentine (RPT) macrophages. D-mannosamine conjugated PLGA-polyethylene glycol (PLGA-PEG) through EDC/NHS coupling chemistry, and...
Tuberculosis (TB) is a leading cause of death amongst infectious diseases. The poor response to antitubercular agents necessitates the long-term use high drug doses, resulting in low patient compliance, which main reason for chemotherapy failure and contributes development multidrug-resistant TB. Patient non-compliance has been major obstacle successful management aim this work was develop characterise rifapentine (RPT)-loaded PLGA-based nanoparticles (NPs) reducing dosing...
Background: Since the poor response to existing anti-tuberculosis drugs and low drug concentration in local bone tissues, traditional therapy does not result satisfactory treatment of osteoarticular tuberculosis. Thus, we report a rifapentine release system with imparted targeting potential using tetracycline (TC) -modified nanoparticles (NPs). Methods: TC was conjugated PLGA-PEG copolymer via DCC/NHS technique. Rifapentine-loaded NPs were prepared by premix membrane emulsification The...
To critically examine and elucidate the diagnostic pitfalls of spinal echinococcosis. SUMMARY OF PATIENTS: From October 1957 to June 2006, 25 consecutive cases drawn from 5721 echinococcosis were collected in First Affiliated Hospital Xinjiang Medical University. The selected comprised 11 males 14 females; all treated with debridement operations. average age was 28.3 years (15 56 y). duration infestation hydatid disease 3.2 (0.5 12 Nineteen underwent magnetic resonance imaging (MRI)...
Hydatid diseases of the pelvic bone are rare, generally incurable, and have high rates recurrence.We report nine cases osseous hydatidosis involving pelvis. Patients were treated through different surgical options, including simple debridement, cement filling with or without internal fixation, reconstruction using a pedicle screw-rod system, hemipelvic replantation after liquid nitrogen devitalization combined femoral prosthesis replacement. The therapy was completed by medical treatment...
Hemipelvic resections for primary bone tumours require reconstruction to restore weight bearing along anatomic axes. However, of the pelvic arch remains a major surgical challenge because high rate associated complications. We used pedicle screw-rod system reconstruct pelvis, and purpose this investigation was assess oncology, functional outcome complication following procedure. The study investigate operative indications technique in stability sacroiliac joint after resection tumours....
Spinal hydatid disease is rare and remains a serious health problem associated with high rates of recurrence. We report our experience in treating patients thoracic spinal hydatidosis through single-center case-series study.Sixteen were treated center between 1995 2017. A total en bloc spondylectomy (TES) was performed three patients. Five posterior decompression stabilization after removing the involved elements. The remaining underwent curettage resection infected bone. therapy completed...
The present study reports a rare case of synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome in an adult male. 42‑year‑old man complained skin lesions, chest pain lumbago. Laboratory evaluations demonstrated elevated erythrocyte sedimentation rate increased levels C‑reactive protein. Computerized tomography, bone scintigraphy magnetic resonance imaging revealed multiple lesions. A diagnosis SAPHO was made. Non‑steroidal anti‑inflammatory drugs, alendronate sodium steroids...