A5101742745- Surface Modification and Superhydrophobicity
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Adhesion, Friction, and Surface Interactions
- Fluid Dynamics and Heat Transfer
- Bone Metabolism and Diseases
- Bone Tissue Engineering Materials
- Tribology and Lubrication Engineering
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Free Radicals and Antioxidants
- NF-κB Signaling Pathways
- Corrosion Behavior and Inhibition
- Tendon Structure and Treatment
- Microfluidic and Bio-sensing Technologies
- Hip disorders and treatments
- Antimicrobial Resistance in Staphylococcus
- Polymer Surface Interaction Studies
- Synthesis and bioactivity of alkaloids
- Surgical site infection prevention
- Moringa oleifera research and applications
- Thermal Radiation and Cooling Technologies
- Advanced Thermoelectric Materials and Devices
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Phytochemicals and Antioxidant Activities
- Beetle Biology and Toxicology Studies
First Affiliated Hospital of Harbin Medical University
2010-2025
Harbin Medical University
2010-2024
Post-traumatic related limb osteomyelitis (PTRLO) is a complex bone infection. Currently, there are no available microbial data on national scale that can guide appropriate antibiotic selection, and explore the dynamic changes in dominant pathogens over time. This study aimed to conduct comprehensive epidemiological analysis of PTRLO China.The was approved by Institutional Research Board (IRB), 3526 patients were identified from 212 394 traumatic fracture at 21 hospitals between 1 January...
Radial Extracorporeal Shock Wave Therapy (rESWT) is applied as a conservative treatment modality in orthopedics, yet its effectiveness addressing aseptic loosening of cementless joint prostheses remains unclear. Through animal experimentation, we have revealed that titanium particle-induced osteolysis rat model, rESWT intervention significantly increased periprosthetic bone density compared to untreated controls, concurrently reducing osteolytic lesion area and lowering serum IL-1β levels....
Inspired by the bionic fish scale surfaces containing micro/nanostructured arrays, herein, applications of lubricant‐impregnated anisotropic slippery (LIASSs) using laser ablation aluminum–magnesium alloys are proposed. Different hydrophobic properties presented on LIASSs along parallel direction and reverse defined as directions A B micro/nanostructures. self‐assembled solid–liquid interface friction test device is set up to demonstrate drag reduction property LIASSs. The ratios found be...
Solid/liquid interface drag reduction is a hot topic and it of great significance to reduce energy consumption in industrial field. Herein, we prepare slippery liquid-infused porous surface (SLIPS) with excellent self-healing super-slippery properties. Through adjusting the density Zn-Al LDH films on aluminium foil, ability rough capture lubricant oil studied. The SLIPS can repel various liquids such as water, white mineral ethanol. By testing friction solid/liquid interface, ratio 20–30%...
Hydroxyapatite can deliver drugs, and its composite material is capable of repairing bone defects in tumors. This study was conducted to evaluate the effect materials on tumor growth inhibition induction. Composites containing drug delivery compounds were synthesized by coprecipitation freeze‐drying then characterized scanning electron microscopy (SEM), X‐ray diffraction (XRD), Fourier‐transform infrared spectroscopy (FTIR). In addition, hydroxyapatite nanoparticles (nano‐SHAP) proliferation...
Wear particles serve a central role in periprosthetic osteolysis, which leads to the aseptic loosening of prostheses. In present study lentiviral vector was constructed silence macrophage colony stimulating factor (M‑CSF) and receptor activator nuclear κ‑B ligand (RANKL) genes, synergistically inhibit osteoclast formation differentiation. To confirm calcineurin/nuclear activated T cells (NFAT) pathway we transduced murine macrophage/monocyte RAW264.7 with M‑CSF‑short hairpin...
Periprosthetic osteolysis, involving RANK/RANKL/osteoprotegerin (OPG) and TNF-α/NFκB signaling, contributes to bone resorption inflammation. We constructed lentivirus vectors inhibit TNF-α enhance OPG expression assessed their impacts on wear debris-induced inflammation osteoclastogenesis in an osteoclast/osteoblast coculture system.We transduced mouse osteoblastic MC3T3-E1 cells with Lenti-negative control (Lenti-NC), Lenti-OPG or Lenti-siTNFα-OPG, murine macrophage/monocyte RAW264.7...
Abstract Superhydrophobic surfaces have shown utility applications in drag reduction field. A novel method based on simulation analysis and test experiments is proposed to fabricate a superhydrophobic surface with 3D flower-like micro nano-structures steel ball under an O 2 rich environment. The has water CA of 166 ± 1.5°. sliding angle less than 2°. experiment the untreated fall are built prove validity reducing resistance. ratio beyond 53% opposed water. model simulate analyze solid-liquid...
<title>Abstract</title> Extracorporeal shock wave therapy (ESWT) is a conservative orthopedic treatment that has been shown to be effective in variety of diseases; however, its effectiveness addressing sterile prosthesis loosening remains uncertain. This study aimed establish model periprosthetic osteolysis and assess the impact ESWT on induced by wear particles. The findings indicated group receiving exhibited an increase bone mineral density, alongside reduction extent osteolysis, quantity...
Bi particles are dispersed in hydroxyapatite/ strontium/chitosan material by mixed coprecipitation and freeze-drying method. In oder to assess their anti-tumor, osteogenic antibacterial effects, SEM, EDS, FIRT, XRD, hemolysis swell experiments were used the physical properties of material. Cytotoxicity assays, PCR techniques effects on bone cells, osteosarcoma cells. Flow cytometry was evaluate effect composites inhibitory Staphylococcus aureus evaluated antimicrobial susceptibility test....
Background: We aimed to carry out a comprehensive multiple-center epidemiological study of post-traumatic related limb osteomyelitis (PTRLO) in China.Methods: Approved by the Institutional Research Board (IRB), 3,526 PTRLO patients were identified from 212,394 traumatic fracture 21 hospitals between January 1st, 2008- December 31st, 2017 conduct an retrospective analysis, which includes dynamic changes infection rate (IR), pathogens, risk factors, and antibiotics resistant sensitivity during...