A5100454410- Glioma Diagnosis and Treatment
- Vascular Malformations Diagnosis and Treatment
- Orthopaedic implants and arthroplasty
- Bone Tissue Engineering Materials
- Extracellular vesicles in disease
- Tendon Structure and Treatment
- MicroRNA in disease regulation
- Cerebrospinal fluid and hydrocephalus
- Brain Metastases and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Sirtuins and Resveratrol in Medicine
- Chromatin Remodeling and Cancer
- Meningioma and schwannoma management
- RNA Research and Splicing
- Immune cells in cancer
- Cancer-related molecular mechanisms research
- interferon and immune responses
- Mitochondrial Function and Pathology
- Angiogenesis and VEGF in Cancer
- Cancer Genomics and Diagnostics
- Moyamoya disease diagnosis and treatment
Harbin Medical University
2012-2025
First Affiliated Hospital of Harbin Medical University
2024-2025
Sun Yat-sen University
2022
Zhongshan Hospital
2022
The First Affiliated Hospital, Sun Yat-sen University
2022
Zhongshan People's Hospital
2022
University of Electronic Science and Technology of China
2019-2022
Huazhong University of Science and Technology
2021
First Hospital of Jilin University
2015-2021
Jilin University
2015-2021
Glioblastomas (GBMs) containing foci that resemble oligodendroglioma are defined as GBM with component (GBMO). However, whether GBMO is a distinct clinicopathological variant of or merely represents divergent pattern differentiation remains controversial. We investigated 219 consecutive primary GBMs, which 40 (18.3%) were confirmed GBMOs. The clinical features and genetic profiles the GBMOs analyzed compared conventional GBMs. group showed more frequent tumor-related seizures (P= .027),...
Radial Extracorporeal Shock Wave Therapy (rESWT) is applied as a conservative treatment modality in orthopedics, yet its effectiveness addressing aseptic loosening of cementless joint prostheses remains unclear. Through animal experimentation, we have revealed that titanium particle-induced osteolysis rat model, rESWT intervention significantly increased periprosthetic bone density compared to untreated controls, concurrently reducing osteolytic lesion area and lowering serum IL-1β levels....
Abstract Glioma is the most general primary and lethal intracranial malignant tumor. Pterostilbene (PTE), an analog of stilbene resveratrol, has attracted attention in recent years due to its significant antitumor activity multiple solid tumors; however, effect on drug-resistant glioma cells underlying mechanism have not yet been reported. In this study, we found that pterostilbene inhibited proliferation, induced intrinsic mitochondria-mediated apoptosis caused S phase arrest, migration...
Phospholipase C beta 1 (PLCβ1) expresses in gliomas and cultured glial cells, but its expression is barely detectable normal cells. We analyzed data from Gene Expression Omnibus (GEO-GDSxxx), The Cancer Genome Atlas (TCGA), the Repository for Molecular Brain Neoplasia Data (REMBRANDT) to explore potential role of PLCβ1 as a biomarker high-grade glioma (HGG). significantly higher grade III than that IV GDS1815 (n = 24 vs. 76), GDS1962 19 81), GDS1975 26 59). In GDS1815, correlates with...
Glioblastoma (GBM) is the most common and devastating primary malignant intracranial tumor in adults. The current first‑line treatment for patients with newly diagnosed GBM surgical resection followed by radiotherapy plus concomitant adjuvant temozolomide. This protocol may prolong survival period of patient, however it not curative more effective therapeutic strategies are required. a type highly vascularized increased expression levels vascular endothelial growth factor (VEGF), which...
Low-grade gliomas (LGGs) are a highly heterogeneous group of slow-growing, lethal, diffusive brain tumors. Temozolomide (TMZ) is frequently used primary chemotherapeutic agent for LGGs. Currently there no consensus as to the optimal biomarkers predict efficacy TMZ, which calls decision-making each patient while considering molecular profiles. glioma data sets were retrieved from The Cancer Genome Atlas. Cox regression and survival analyses applied identify clinical features significantly...
Objective: This study aimed to explore the immediate postoperative and long-term outcomes of central neurocytoma (CN) based on 15 years experience in our institution. Methods: single-institution collected data 43 patients with CN who underwent surgery between 2005 2020. We reviewed clinical, outcome, outcome patients. More specifically, we divided complications into neurological regional groups. Results: Among surgery, transcortical (72.1%) or transcallosal (25.6%) approach was used. There...
<title>Abstract</title> Extracorporeal shock wave therapy (ESWT) is a conservative orthopedic treatment that has been shown to be effective in variety of diseases; however, its effectiveness addressing sterile prosthesis loosening remains uncertain. This study aimed establish model periprosthetic osteolysis and assess the impact ESWT on induced by wear particles. The findings indicated group receiving exhibited an increase bone mineral density, alongside reduction extent osteolysis, quantity...