A5101507290- Glioma Diagnosis and Treatment
- RNA Research and Splicing
- Global Cancer Incidence and Screening
- Cancer Immunotherapy and Biomarkers
- Advanced MRI Techniques and Applications
- Cancer Risks and Factors
- Cardiac Imaging and Diagnostics
- Ferroptosis and cancer prognosis
- Colorectal Cancer Screening and Detection
- Bioinformatics and Genomic Networks
- Quality and Supply Management
- Meningioma and schwannoma management
- Plant-Microbe Interactions and Immunity
- Cell death mechanisms and regulation
- Extracellular vesicles in disease
- Lanthanide and Transition Metal Complexes
- Remote Sensing and Land Use
- Plant tissue culture and regeneration
- Cancer-related molecular mechanisms research
- Glycosylation and Glycoproteins Research
- Adipose Tissue and Metabolism
- Nutrition and Health in Aging
- Ion channel regulation and function
- Lung Cancer Research Studies
- Cardiomyopathy and Myosin Studies
Wuhan University
2023-2025
Renmin Hospital of Wuhan University
2023-2025
Xiangya Hospital Central South University
2023-2025
Central South University
2023-2025
Liaoning Cancer Hospital & Institute
2025
Dalian University of Technology
2025
China Medical University
2025
Xiamen University
2024
Sun Yat-sen University Cancer Center
2021-2022
Sun Yat-sen University
2021-2022
A substantial body of evidence suggests that cytoreductive surgery is a prerequisite to prolonging survival in patients with glioblastoma (GBM).To evaluate the safety and impact "supratotal" resections beyond zone enhancement seen on magnetic resonance imaging scans, using subpial technique.We retrospectively evaluated 86 consecutive primary GBM, managed by senior author, resection technique or without carmustine (BCNU) wafer implantation. Multivariate Cox proportional hazards regression was...
Abstract Large temperature difference is reported to be a risk factor for human health. However, little evidence has the effects of fluctuation on sarcopenia, senile disease characterized by loss muscle mass and function. Here, we demonstrate that higher diurnal range in humans positive correlation with prevalence sarcopenia. Fluctuated exposure (10–25 °C) accelerates atrophy dampens exercise performance mid-aged male mice. Interestingly, fluctuated alters microbiota composition increased...
Gadolinium-based contrast agents were not approved in the United States for detecting coronary artery disease (CAD) prior to current studies. The purpose of this study was determine sensitivity and specificity gadobutrol detection CAD by assessing myocardial perfusion late gadolinium enhancement (LGE) imaging. Two international, single-vendor, phase 3 clinical trials near identical design, "GadaCAD1" "GadaCAD2," performed. Cardiovascular magnetic resonance (CMR) included gadobutrol-enhanced...
No study has been conducted to investigate the spatial pattern and association of socioeconomic status (such as income) with breast colorectal cancer incidence in Texas, United States. This aimed determine whether median household income was associated risk developing Texas identify higher risks by race/ethnicity geographic areas.This a retrospective cohort an ecological component using aggregated measures at county level. We identified 243,677 women 155,534 men residing 254 counties...
Phospholipase C beta 1 (PLCβ1) expresses in gliomas and cultured glial cells, but its expression is barely detectable normal cells. We analyzed data from Gene Expression Omnibus (GEO-GDSxxx), The Cancer Genome Atlas (TCGA), the Repository for Molecular Brain Neoplasia Data (REMBRANDT) to explore potential role of PLCβ1 as a biomarker high-grade glioma (HGG). significantly higher grade III than that IV GDS1815 (n = 24 vs. 76), GDS1962 19 81), GDS1975 26 59). In GDS1815, correlates with...
Logistic regression models are widely used in case‐control data analysis, and testing the goodness‐of‐fit of their parametric model assumption is a fundamental research problem. In this article, we propose to enhance power test by exploiting monotonic density ratio model, which case control densities assumed be monotone function. We show that such naturally induced retrospective sampling design under alternative hypothesis. The pool‐adjacent‐violator algorithm adapted solve for constrained...
Few studies have examined the cancer incidence trends in state of Texas, and no study has ever been conducted to compare temporal breast colorectal Texas with those National Cancer Institute's Surveillance, Epidemiology End Results (SEER) United States. This aimed conduct a parallel comparison between Registry SEER on from 1995 2011. A total 951,899 patients were included. Age-adjusted was 134.74 per 100,000 131.78 1995-2011, whereas age-adjusted 50.52 49.44 SEER. Breast increased 2001,...
Obesity is a process of fat accumulation due to the imbalance between energy intake and consumption. Long noncoding RNA (lncRNA) Hnscr crucial for metabolic regulation, but its roles in lipid metabolism during obesity are still unknown. In this article, we found that expression gradually decreased adipose tissues diet-induced obese mice. Furthermore, deletion promoted an increase body weight tissue by upregulating lipogenesis genes downregulating lipolysis inguinal white (iWAT) brown tissue....
Codonopsis pilosula, a traditional Chinese medicinal and edible plant, contains several bioactive components. However, the biosynthetic mechanism is unclear because of difficulties associated with functional gene analysis. Therefore, it important to establish an efficient genetic transformation system for function In this study, we established highly Agrobacterium-mediated callus C. pilosula using stems as explants. After being pre-cultured 3 days, explants were infected Agrobacterium...
Background: Immune checkpoint inhibitors have been successfully used in a variety of tumors, however, the efficacy immune blockade therapy for patients with glioma is limited. In this study, we tried to clarify gene expression signatures related prognosis gliomas and construct signature predict survival gliomas. Methods: Calcium-related differential expressed genes (DEGs) between normal brain tissues were comprehensively analyzed two independent databases. Univariate, multivariate Cox...
As a relatively new remote sensing means, unmanned aerial vehicle (UAV) has been widely used in the fields of agriculture, forestry, and urban construction surveying mapping because its low cost, high efficiency, flexibility. This paper introduces UAV sensor technology applications different fields. First, core role sensors systems is introduced, including development multispectral, hyperspectral, LiDAR technologies their sensing. Then, working principles, technical characteristics,...
This study aims to examine how various types of relational attributes can be beneficial supply flexibility in terms physical and purchasing flexibility. Using survey data from a sample SMEs mainland China, we demonstrate that closeness is positively related both We also find capability with flexibility, but not Theoretical managerial implications are discussed.
BACKGROUND: Phospholipase C beta 1 (PLCβ1) expresses in glioma tissue and cultured glial cells, but barely detectable normal cells. Whether PLCβ1 gene expression plays a pathological role has not been studied. METHODS: We analyzed data from Gene Expression Omnibus (GEO-GDSxxx), The Cancer Genome Atlas (TCGA), the Repository for Molecular Brain Neoplasia Data (REMBRANDT) to investigate potential of high-grade (HGG). RESULTS: In GDS1815, correlates with known proneural (PN) signature genes;...
Glioblastoma multiforme (GBM) is the most aggressive and common glial tumor. Historical data shows that median overall survival (OS) 14.6 months with maximum safe resection followed by radiation chemotherapies. We have been treating recurrent GBM patients triple chemotherapies [Temozolomide (TMZ), bevacizumab (BV) Irinotecan (CPT-11)] since 2010. also offer tumor fields (TTFs) for following FDA approval participated in EF-14 clinical trial newly diagnosed from 2011. Here we report OS of our...
BACKGROUND: Despite advances in chemotherapy and surgical approaches, the median overall survival (OS) for patients with GBM remains poor. A “supra-maximal” resection, using sub-pial technique low-grade gliomas aims to remove immediately proximate abnormal tissue beyond zone of enhancement on MRI. The purpose this study is evaluate feasibility benefit GBM. METHODS: We retrospectively evaluated 86 consecutive operated primary or without BCNU wafer implantation adjuvant therapy. Presenting...