A5102027958- Effects and risks of endocrine disrupting chemicals
- Toxic Organic Pollutants Impact
- Exercise and Physiological Responses
- Adipose Tissue and Metabolism
- Biological and pharmacological studies of plants
- Pluripotent Stem Cells Research
- Air Quality and Health Impacts
- Reproductive biology and impacts on aquatic species
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Lipid metabolism and biosynthesis
- Phytochemistry and biological activity of medicinal plants
- RNA Research and Splicing
- Sperm and Testicular Function
- Heart Rate Variability and Autonomic Control
- Growth Hormone and Insulin-like Growth Factors
- Nutrition and Health in Aging
- Genetic Associations and Epidemiology
- Hypothalamic control of reproductive hormones
- Microplastics and Plastic Pollution
- Obesity, Physical Activity, Diet
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Nutrition, Genetics, and Disease
- Cardiac Health and Mental Health
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Guangzhou Medical University
2019-2023
Xiangya Hospital Central South University
2022-2023
Central South University
2022-2023
Guangzhou Women and Children Medical Center
2023
Guangzhou Psychiatric Hospital
2022
Guangzhou University of Chinese Medicine
2022
Chinese University of Hong Kong
2010-2016
Shaanxi Provincial People's Hospital
2015
Shanxi Medical University
2015
Second Affiliated Hospital of Xi'an Jiaotong University
2015
Abstract Large temperature difference is reported to be a risk factor for human health. However, little evidence has the effects of fluctuation on sarcopenia, senile disease characterized by loss muscle mass and function. Here, we demonstrate that higher diurnal range in humans positive correlation with prevalence sarcopenia. Fluctuated exposure (10–25 °C) accelerates atrophy dampens exercise performance mid-aged male mice. Interestingly, fluctuated alters microbiota composition increased...
In order to evaluate the expression profile of follicle-stimulating hormone receptor (FSHR) mRNA in ovary Zi geese during developmental and egg laying stages, levels FSHR at ages 1 day, 1, 2, 3, 4, 5 8 months (n=8, respectively) were examined by quantitative real-time PCR (qRT-PCR). The results showed that was greater age compared day (P < 0.05). Particularly, much greater, 1.86 +/- 0.14, 3.50 0.19 5.11 0.27 fold, respectively, 0.01). level 2 3 1.35 0.12, 1.31 0.05 1.28 0.09 fold indicate...
Abstract Thermogenesis in brown adipose tissue (BAT) declines with aging, however, the underlying mechanism remains unclear. Here, we show that expression of Y‐box binding protein 1 (YB‐1), a critical DNA/RNA protein, decreased BAT aged mice due to reduction microbial metabolite butyrate. Genetic ablation YB‐1 accelerated diet‐induced obesity and thermogenic dysfunction. In contrast, overexpression was sufficient promote thermogenesis, thus alleviating insulin resistance. Interestingly, had...
Major depressive disorder (MDD) is a common psychiatric disease and leading cause of disability worldwide. Handgrip strength (HGS) as an objective physical fitness test practical index for identifying many diseases. Previous studies drew different conclusions about the relationship between HGS MDD.We aim to explore whether has effect on risk MDD.HGS-related single-nucleotide polymorphisms identified by genome-wide association study were used instrumental variables in this Mendelian...
The protective effects of vitamin E (45, 150, and 500 mg/kg/d) against reproductive toxicity induced in male Kunming mice by intragastric administration 120 mg/kg/d bisphenol A was investigated. After two weeks, relative organ weights, sperm counts, abnormality rates serum testosterone concentrations were determined. Epididymal counts significantly decreased, increased, dramatically reduced following exposure. Vitamin treatment led to a marked increase numbers decrease the proportion...
Objective To investigate the distribution of critical values adults in Beijing, to provide evidence for formulation Standardized Management Guideline Critical Values, order promote accurate management values. Methods A total 110 398 data from tertiary and above medical institutions during January 1 May 31 2015 Beijing were collected by way on-site inspection, covering disciplines hematology, clinical chemistry, coagulation blood gas analysis. Fristly, selected classified factor...