- Regulation of Appetite and Obesity
- Genomics and Phylogenetic Studies
- Adipose Tissue and Metabolism
- Biochemical Analysis and Sensing Techniques
- Cancer-related molecular mechanisms research
- Aquaculture disease management and microbiota
- Fish Biology and Ecology Studies
- Fish Ecology and Management Studies
- Genetic diversity and population structure
- Molecular Biology Techniques and Applications
- Aquaculture Nutrition and Growth
- Neurobiology and Insect Physiology Research
- Identification and Quantification in Food
- Physiological and biochemical adaptations
- Genetic and phenotypic traits in livestock
- Circular RNAs in diseases
- Chromosomal and Genetic Variations
- Neuropeptides and Animal Physiology
- Enzyme Production and Characterization
- Animal Virus Infections Studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Reproductive biology and impacts on aquatic species
- Muscle Physiology and Disorders
- Plant Stress Responses and Tolerance
- Enzyme Catalysis and Immobilization
Southwest University
2016-2025
Nanjing Tech University
2020-2025
Research Center for Eco-Environmental Sciences
2021-2024
Chinese Academy of Sciences
2021-2024
Chang'an University
2024
Ministry of Education of the People's Republic of China
2022
Tibet Academy of Agricultural and Animal Husbandry Sciences
2017-2021
Sichuan Agricultural University
2012-2016
Chinese Academy of Forestry
2013
Hangzhou Dianzi University
2008
Domesticated organisms have experienced strong selective pressures directed at genes or genomic regions controlling traits of biological, agricultural medical importance. The genome native and domesticated pigs provide a unique opportunity for tracing the history domestication identifying signatures artificial selection. Here we used whole-genome sequencing to explore genetic relationships among European pig Berkshire breeds that are distributed worldwide identify footprints left by...
Ecological risk assessment (ERA) is an important element in territorial spatial planning, and the integration of ecosystem services into ERA a current hot topic. In this study, taking Tibetan Plateau as example, two-dimensional matrix constructed based on probability occurrence possible loss caused by for ecological assessment, with topographic sensitivity, resilience, landscape vulnerability, sensitivity representations, degradation key representations to improve traditional model. The...
Global warming has heightened the severity and frequency of extreme high-temperature events, presenting challenges to fish survival negatively affecting production fishery. Gymnocypris eckloni, native Tibetan Plateau, is widely cultured in southwest China. Its sensitivity heat makes it a suitable model for studying impact high temperatures on fish. The heart vital organ survival, while relatively understudied concerning hearts. In this study, G. eckloni was subjected seven-day exposure 27 °C...
Abstract Recent genomic analyses of evolutionary radiations suggest that ancient introgression may facilitate rapid diversification and adaptive radiation. The loach genus Triplophysa, a with most species endemic to Tibetan Plateau, shows ecological diversity evolution represents potential example radiation linked the uplift Plateau. Here, we interrogate complex history Triplophysa fishes through analysis whole-genome sequences. By reconstructing phylogeny quantifying across this clade,...
The dynamic changes in plateau river ecosystems and the driving mechanisms of environmental factors have garnered significant attention. Phytoplankton, a core component aquatic ecosystems, can directly reflect environment. This study focuses on phytoplankton Lhasa River Basin, including riverbed from source to mouth, five largest tributaries, two adjacent wetlands. We analyzed spatial temporal variation characteristics explored based four field surveys conducted between September 2019 March...
MicroRNAs (miRNAs) are a type of non-coding small RNA ~22 nucleotides in length that regulate the expression protein coding genes at post-transcriptional level. Glycolytic and oxidative myofibers, two main types skeletal muscles, play important roles metabolic health as well meat quality production pig industry. Previous profile studies different muscle have focused on these aspects mRNA proteins; nonetheless, an explanation miRNA transcriptome differences between distinct muscles is long...
Whole-genome duplications (WGDs) of Schizothoracinae are believed to have played a significant role in speciation and environmental adaptation on the Qinghai-Tibet Plateau (QTP). Here, we present genome for Schizothorax o'connori, QTP endemic fish showed species as young tetraploid with recent WGD later than ∼1.23 mya. We exhibited that massive insertions between duplicated genomes caused by transposon bursts could induce mutagenesis adjacent sequences alter expression neighboring genes,...
Abstract Animal genomes in the Qinghai-Tibetan Plateau provide valuable resources for scientists to understand molecular mechanism of environmental adaptation. Tibetan fish species play essential roles local ecology; however, genomic information native fishes was still insufficient. Oxygymnocypris stewartii , belonging genus, Schizothoracinae subfamily, is a plateau living within elevation from roughly 3,000 m 4,200 m. In this report, PacBio and Illumina sequencing platform were used...
In this study, the full‐length neuropeptide Y ( npy ) complementary (c) DNA was cloned in ya fish Schizothorax prenanti . cDNA composed of 789 nucleotides with a 288 nucleotide open reading frame encoding protein 96 amino acids. The deduced acid sequences contained 28 acids signal peptide followed by 36 mature (NPY). mRNA expressed mainly brain and eye as detected real‐time quantitative polymerase chain reaction RT‐PCR rt‐qPCR ). S. NPY detectable from blastulation to hatch, suggesting that...
Abstract The Schizothoracinae fishes, endemic species in the Tibetan Plateau, are considered as ideal models for highland adaptation and speciation investigation. Despite several transcriptome studies fishes have been reported before, information of is still lacking. To obtain comprehensive data Schizothoracinae, a total 183 samples from 14 representative species, were sequenced de novo assembled. As result, about 1,363 Gb clean was obtained. After assembly, we 76,602–154,860 unigenes each...
Abstract Remora albescens , also known as white suckerfish, recognized for its distinctive suction-cup attachment behavior and medicinal significance. In this study, we produced a high-quality chromosome-level genome assembly of R. through the integration 23.87 Gb PacBio long reads, 64.54 T7 short 88.63 Hi-C data. Initially, constructed contig-level totaling 605.30 Mb with contig N50 23.12 Mb. Subsequently, employing technology, approximately 99.68% (603.38 Mb) was successfully assigned to...