A5063172593- Prenatal Substance Exposure Effects
- Maternal Mental Health During Pregnancy and Postpartum
- Pregnancy and Medication Impact
- Anesthesia and Neurotoxicity Research
- Gestational Diabetes Research and Management
- Maternal and fetal healthcare
- Infant Development and Preterm Care
- Pregnancy and preeclampsia studies
- Anesthesia and Sedative Agents
- Cardiac, Anesthesia and Surgical Outcomes
Massachusetts General Hospital
2017-2020
Harvard University
2017-2020
Brigham and Women's Hospital
2018
<b>Objectives</b> To assess the impact of in utero co-exposure to psychotropic medications and opioids on incidence severity neonatal drug withdrawal. <b>Design</b> Observational cohort study. <b>Setting</b> Nationwide sample pregnancies publicly insured women US, nested Medicaid Analytic eXtract (2000-10). <b>Participants</b> 201 275 pregnant with public insurance who were exposed around time delivery their liveborn infants. <b>Interventions</b> In exposure...
Summary Introduction Understanding the duration of pediatric general anesthesia exposure in contemporary practice is important for identifying groups at risk long exposures and designing trials examining associations between neurodevelopmental outcomes. Methods We performed a retrospective cohort analysis to estimate during 2010‐2015 using National Anesthesia Clinical Outcomes Registry. Results A total 1 548 021 anesthetics were included. Median was 57 minutes (IQR: 28‐86) with 90th...
Abstract Background The Medicaid Analytic eXtract (MAX) is a health care utilization database from publicly insured individuals that has been used for studies of drug safety in pregnancy. Claims‐based algorithms defining many important maternal and neonatal outcomes have not validated. Objective To validate claims‐based identifying selected pregnancy MAX using hospital medical records. Methods records mothers who delivered between 2000 2010 within single large healthcare system were linked...
( BMJ . 2017;358:j3326) Neonatal abstinence syndrome is a recognized complication of intrauterine exposure to opioids. can manifest in number different ways, from difficulty feeding and sleeping more severe complications such as impaired thermoregulation, seizures, failure thrive, respiratory distress. Because pregnant women who are using an opioid often also use psychotropic medications, there concerns about potential interactions between the drugs leading increase occurrence severity...