A5040986266- Waste Management and Environmental Impact
- Agriculture, Plant Science, Crop Management
- Nanoparticles: synthesis and applications
- Botany and Plant Ecology Studies
- Tuberculosis Research and Epidemiology
- Agricultural economics and policies
- Ion channel regulation and function
- Effects and risks of endocrine disrupting chemicals
- Pesticide Exposure and Toxicity
- Potato Plant Research
- Mycobacterium research and diagnosis
- Healthcare and Venom Research
- Graphene and Nanomaterials Applications
- Healthcare and Environmental Waste Management
- Carcinogens and Genotoxicity Assessment
- Immunotherapy and Immune Responses
- Air Quality and Health Impacts
- Nanoparticle-Based Drug Delivery
- Galectins and Cancer Biology
- Ovarian cancer diagnosis and treatment
- Retinoids in leukemia and cellular processes
- Integrated Water Resources Management
- Vitamin D Research Studies
- Reproductive System and Pregnancy
- Venomous Animal Envenomation and Studies
Instytut Medycyny Wsi im. Witolda Chodźki
2015-2023
Józef Piłsudski University of Physical Education in Warsaw
2020
Wroclaw Medical University
2013
Jagiellonian University
2007
Abstract Metallic nanoparticles due to their small size and unique physico-chemical characteristics have found excellent applications in various branches of industry medicine. Therefore, for many years a growing interest has been observed among the scientific community improvement our understanding impact on living organisms, especially humans. Considering delicate structure central nervous systemit is one organs most vulnerable adverse effects metallic nanoparticles. For that reason, it...
We have developed a short-term organ culture model for the study of biochemical and morphological development late gestation fetal rat lung. Explants (1 mm3) 19-day lung were cultured in an oxygen enriched environment presence synthetic serum-free medium 3 days. Morphological maturation continued culture. The rate incorporation choline into disaturated phosphatidylcholine content this phospholipid explants increased vitro pattern very similar to that which occurs vivo. activities kinase...
Dietary supplements (DS) are used by about 30–50% of adults in developed countries. However, only a few studies have compared the characteristics DS users different nations. This study aimed to identify and compare selected health-related behaviors from three European A total 3,588 (32.08 ± 8.04 years) Poland (1,030 females, 287 males), Germany (994 190 United Kingdom (911 176 males) were included analysis. The was based on self-administered survey consisting 70 questions regarding baseline...
On the contrary to adult population exposed pesticides, mostly on occupational basis, rural children are pesticides deposited in environment. However, even this constant, distributed time exposure low concentrations of may led permanent health disorders and limit children's harmonious development.The main objective study was evaluate usefulness aacetylcholinesterase (AChE) butyrylcholinesterase (BuChE) activity determination as a marker environmental pesticides. An additional aim sweat...
The fast-growing use of nanomaterials in everyday life raises the question about safety their use. Unfortunately, risks associated with nanoparticles (NPs) have not yet been fully assessed. majority studies conducted so far at molecular and cellular level focused on a single-type exposure, assuming that NPs act as only factor. In natural environment, however, we are likely exposed to mixture nanoparticles, whose interactions may modulate impact living organisms. This study aimed evaluate...
Abstract Matrix metallopeptidases, commonly known as matrix metalloproteinases (MMPs), are a group of proteolytic enzymes whose main function is the remodeling extracellular matrix. Changes in activity these observed many pathological states, including cancer metastases. An increasing body evidence indicates that nanoparticles (NPs) can lead to deregulation MMP expression and/or both vitro and vivo . In this work, we summarized current state knowledge on impact NPs MMPs. The literature...
Silver nanoparticles (AgNPs) are used in many fields of industry and medicine. Despite the well-established antimicrobial activity, AgNPs foreseen to be as anticancer drugs due unusual feature-inability induce drug resistance cancer cells. The aim study was assess biological activity against MDA-MB-436 cells were derived from triple-negative breast cancer, a type with poor prognosis is particularly difficult cure. toxic probable mechanism toxicity induction oxidative stress. These promising...
AMA Kapka-Skrzypczak L, Wolinska E, Szparecki G, Czajka M, Skrzypczak M. The immunohistochemical analysis of membrane-bound CD55, CD59 and fluid-phase FH FH-like complement inhibitors in cancers ovary corpus uteri origin. Central European Journal Immunology. 2015;40(3):349-353. doi:10.5114/ceji.2015.54598. APA Kapka-Skrzypczak, L., Wolinska, E., Szparecki, G., Czajka, M., & Skrzypczak, (2015). Immunology, 40(3), 349-353. https://doi.org/10.5114/ceji.2015.54598 Chicago Lucyna, Ewa Grzegorz...
Nuclear factor kappa B (NF-κB) signalling pathway plays a central role in the regulation of cellular response to stress. The aim study was investigate ability silver nanoparticles (AgNPs), gold (AuNPs), CdTe quantum dots (CdTeQDs) or their binary mixtures stimulate NF-κB binding HepG2 cells. A dual luciferase reporter system used binding.Cells were transiently transfected with firefly and Renilla expression plasmid as transfection efficiency control. Twenty- four hours after transfection,...
The aim of the present study was to evaluate role interleukin (IL)-6 and IL-8 on expression membrane-bound complement inhibitors membrane attack complex-inhibitory protein (CD59) decay-accelerating factor (CD55), in human ovarian carcinoma A2780 cell line, which is a non-producing IL-6 line that does exhibit responsiveness, due presence receptors. Extracellular levels system were evaluated by western blotting reverse transcription-quantitative polymerase chain reaction. Cellular localization...
Epithelial cell adhesion molecule (EpCAM), which is expressed in the majority of epithelial tissues, exhibits tumor growth promoting abilities and overexpressed human ovarian cancer. Therefore, EpCAM considered to be a promising target for specific immune‑based therapies. The present study evaluated role IL‑6 IL‑8 expression A2780 cancer line. Furthermore, cellular localization protein cells was determined effect inhibition on proliferation investigated. An MTT assay demonstrated that...