N. Mills

ORCID: 0000-0003-3808-867X
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About
Contact & Profiles
Research Areas
  • Respiratory Support and Mechanisms
  • Airway Management and Intubation Techniques
  • Transplantation: Methods and Outcomes
  • Organ Transplantation Techniques and Outcomes
  • Renal Transplantation Outcomes and Treatments
  • COVID-19 Clinical Research Studies
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Medical Imaging and Pathology Studies
  • Infection Control and Ventilation
  • Tracheal and airway disorders
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Nosocomial Infections in ICU
  • Pneumothorax, Barotrauma, Emphysema
  • Pleural and Pulmonary Diseases
  • Cardiac, Anesthesia and Surgical Outcomes
  • Venous Thromboembolism Diagnosis and Management
  • Metabolism and Genetic Disorders
  • Pharmacological Effects and Toxicity Studies
  • Inhalation and Respiratory Drug Delivery
  • COVID-19 and healthcare impacts
  • Diet and metabolism studies
  • Long-Term Effects of COVID-19
  • Pericarditis and Cardiac Tamponade
  • Cardiac Structural Anomalies and Repair
  • Pulmonary Hypertension Research and Treatments

Cambridge University Hospitals NHS Foundation Trust
2023

Temple University Hospital
2020-2022

Temple University
2020-2021

Invasive mechanical has been associated with high mortality in COVID-19. Alternative therapy of flow nasal (HFNT) greatly debated around the world for use COVID-19 pandemic due to concern increased healthcare worker transmission.This was a retrospective analysis consecutive patients admitted Temple University Hospital Philadelphia, Pennsylvania, from 10 March 2020 24 April moderate-to-severe respiratory failure treated HFNT. Primary outcome prevention intubation. Of 445 COVID-19, 104 met our...

10.1136/bmjresp-2020-000650 article EN cc-by-nc BMJ Open Respiratory Research 2020-08-01

The use of high-flow nasal therapy (HFNT) to treat COVID-19 pneumonia has been greatly debated around the world due concerns about increased health care worker transmission and delays in invasive mechanical ventilation (IMV). Herein, we analyzed utility noninvasive ROX (ratio oxygen saturation) index predict need for timing IMV.This study aimed assess whether can be a useful score intubation IMV patients receiving HFNT as treatment COVID-19-related hypoxemic respiratory failure.This is...

10.2196/29062 article EN cc-by JMIRx Med 2021-06-04

Abstract Use of high flow nasal therapy (HFNT) to treat COVID-19 pneumonia has been greatly debated around the world due concern for increased healthcare worker transmission and delays in invasive mechanical Ventilation (IMV). Methods A retrospective analysis consecutive patients admitted Temple University Hospital Philadelphia, Pennsylvania, from March 10, 2020, May 17, 2020 with moderate severe respiratory failure treated High Flow (HFNT). HFNT were divided into two groups: only progressed...

10.1101/2020.06.30.20143867 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-07-02

Introduction Use of high flow nasal therapy (HFNT) to treat COVID-19 pneumonia has been greatly debated around the world due concern for increased healthcare worker transmission and delays in invasive mechanical Ventilation (IMV). Herein we analyze utility ROX index predict need timing IMV a retrospective analysis patients with moderate severe hypoxemic respiratory failure treated HFNT. Methods This was 129 consecutive admitted Temple University Hospital Philadelphia, Pennsylvania, from...

10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2624 article EN 2021-05-01

Abstract Invasive mechanical has been associated with high mortality in COVID-19. Alternative therapy of High flow nasal (HFNT) greatly debated around the world for use COVID-19 pandemic due to concern increased healthcare worker transmission. Methods This was a retrospective analysis consecutive patients admitted Temple University Hospital Philadelphia, Pennsylvania, from March 10, 2020, April 24, 2020 moderate severe respiratory failure treated Flow (HFNT). Primary outcome prevention...

10.1101/2020.05.22.20109355 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2020-05-26

Rationale: Coronavirus disease 2019 (COVID-19) has provoked an unprecedented global pandemic. Invasive mechanical ventilation (IMV) rates in COVID-19 have been reported to be from 2.3% 33%. The wide range intubation is attributed part diverging institutional practices for the care of patients presenting with hypoxemic respiratory failure. role high flow nasal therapy (HFNT) treatment controversial and underreported. Objectives: To report a retrospective analysis comparing outcomes treated...

10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2637 article EN 2021-05-01

<h3>Background</h3> Older patients are increasingly being referred for cardiac surgery, consequently novel prognostic markers which reflect physiological reserve and severity of co-morbid disease now required. Forced Expiratory Volume in one second (FEV<sub>1</sub>) is a robust accurate measure pulmonary physiology predicts all-cause mortality, yet the relationship between FEV<sub>1</sub> outcome undergoing surgery unknown. We hypothesised that would predict mortality length hospital stay...

10.1136/jech.2011.142976j.15 article EN Journal of Epidemiology & Community Health 2011-08-01

<sec> <title>BACKGROUND</title> The use of high-flow nasal therapy (HFNT) to treat COVID-19 pneumonia has been greatly debated around the world due concerns about increased health care worker transmission and delays in invasive mechanical ventilation (IMV). Herein, we analyzed utility noninvasive ROX (ratio oxygen saturation) index predict need for timing IMV. </sec> <title>OBJECTIVE</title> This study aimed assess whether can be a useful score intubation IMV patients receiving HFNT as...

10.2196/preprints.29062 preprint EN cc-by 2021-03-24
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