- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac Ischemia and Reperfusion
- Cardiovascular Function and Risk Factors
- Cardiac Arrest and Resuscitation
- TGF-β signaling in diseases
- Cardiac Health and Mental Health
- Nanoparticles: synthesis and applications
- Cardiac Fibrosis and Remodeling
- Cardiac pacing and defibrillation studies
- Aortic Disease and Treatment Approaches
- Pain Mechanisms and Treatments
- Nanoparticle-Based Drug Delivery
- Gold and Silver Nanoparticles Synthesis and Applications
- Folate and B Vitamins Research
- Cardiac tumors and thrombi
- Silymarin and Mushroom Poisoning
- Ion channel regulation and function
- Fluoride Effects and Removal
- Arsenic contamination and mitigation
- Anesthesia and Neurotoxicity Research
Wenzhou Medical University
2017-2023
First Affiliated Hospital of Wenzhou Medical University
2019-2023
Zhejiang University
2011
Silibinin is a traditional medicine and utilized for liver protection with antioxidant, anti-inflammation anti-apoptosis properties. However, its role in myocardial I/R injury the mechanism involved currently unknown. In present study, treatment improves cardiac function limits infarct size, subsequently inhibits fibrotic remodeling mice injury. Mechanistically, silibinin reduces cardiomyocytes apoptosis, attenuates mitochondrial impairment endoplasmic reticulum (ER) stress, alleviates ROS...
Metallic and metal oxide nanoparticles (Nps) have a wide range of applications in various settings including household, cosmetics chemical industries, as well for coatings. Nevertheless, an in-depth study the potential toxic effects these Nps is still needed, order to fulfill mandatory requirement ensuring safety workers, patients general public. In this study, Quick Cell colorimetric assays were used evaluate vitro toxicity different [Fe(II,III)Ox, TiOx, ZnO CeO2] several cell lines. The...
The aim of this study is to assess the influence cardiopulmonary coupling (CPC) based on RCMSE prediction complications and death in patients with acute type A aortic dissection (ATAAD).The system may be nonlinearly regulated, its relationship postoperative risk stratification ATAAD has not been studied.This was a single-center, prospective cohort (ChiCTR1800018319). We enrolled 39 ATAAD. outcomes were in-hospital all-cause readmission or at 2 years.Of participants, 16 (41.0%) developed...
Myocardial infarction continues to pose a significant challenge in clinical practice due the limited therapeutic options available for preventing adverse cardiac remodeling and functional impairment patients, even with early revascularization. The upregulation of Activin A following ischemic injury is crucial determinant cardiovascular outcomes; however, underlying mechanisms remain incompletely understood. Our current study revealed that inhibiting endogenous antagonist follistatin led...