Abstract Motivation: The discovery of solid-binding peptide sequences is accelerating along with their practical applications in biotechnology and materials sciences. A better understanding the relationships between binding affinities or specificities will enable further design novel peptides selected properties interest both engineering medicine. Results: bioinformatics approach was developed to classify by vivo techniques according inorganic properties. Our performs all-against-all...

Some novel 4,5-disubstituted-2,4-dihydro-3H-1,2,4-triazol-3-one (3, 6, 8, 9) derivatives and or 3-(4-methylphenyl)[1,2,4]triazolo[3,4-b][1,3]benzoxazole (5) were synthesized from the reaction of various ester ethoxycarbonylhydrazones (1a-e) with several primary amines. The synthesis 4-amino-5-(4-chlorophenyl)-2-[(5-mercapto-1,3,4-oxadiazol-2-yl)methyl]-2,4-dihydro-3H-1,2,4-triazol-3-one (13) was performed starting 4-Amino-5-(4-chlorophenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (2) by four...

Schizochytrium species is one of the most studied microalgae for production docosahexaenoic acid (DHA) which an omega-3 fatty with positive effects human health. However, high cost and low yield in phase makes optimization cultivation process inevitable. We focus on DHA using sp. different media supplements; glucose, fructose glycerol as carbon variants, proteose peptone tryptone nitrogen variants. The highest biomass (5.61 g/L) total (1.74 were obtained medium was used alternative source...

Binding kinetics of platinum-, silica-, and gold-binding peptides were investigated using a modified surface plasmon resonance spectroscopy (SPR). Platinum binding septa-peptides, quartz-binding dodecapeptides, 14-aa originally selected phage or cell display libraries the mineral pure forms these materials. All synthesized singly to investigate their assess quantitatively specific affinity each its material selection. The also postselection engineered contain multiple copies same original...

A simple, sensitive, facile and low cost methodology, combined with flame atomic absorption spectrometry (FAAS), was employed to evaluate the selective separation preconcentration of Pd(II) ions in environmental samples by using a triazole derivative as an organic coprecipitating agent without carrier element. The developed method systematically investigated different set experimental parameters that influence quantitative recovery ions. accuracy tested analyzing certified reference material...

A new solid phase extraction (SPE) method has been developed for the selective separation and preconcentration of Cu (II) ions in food water samples prior to its flame atomic absorption spectrometry determination. The is based on adsorption Cu(II) - 2-{[4-Amino-3-(4-methylphenyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetyl}-N-phenyl hydrazinecarbothioamide complex Amberlite XAD-8 resin. metal retained resin was eluted with 7.5 mL 2.0 mol L-1 HCl acetone. optimum conditions SPE were...

Background: Gastric cancer is the second most common among malign types. Inefficiency of traditional techniques both in diagnosis and therapy disease makes development alternative novel indispensable. As an to methods, tumor specific targeting small peptides can be used increase efficiency treatment reduce side effects related techniques. The aim this study screening identification individual specifically targeted human gastric cells using a phage-displayed peptide library designing...

Optimum conditions for the removal of Cu(II) ions from both single-component and Cd(II) containing solutions by ligand-modified micellar-enhanced ultrafiltration (LM-MEUF) were determined. Complexation behaviors 20 ligands with investigated in micellar medium SDS at different pH values to determine which could provide selective separation. In this respect, most effective ligand was found be 2,4,6-tri(2-pyridyl)-1,3,5-triazine (TPTZ). presence 6.6 × 10−8 mol L−1 TPTZ feed solution,...

High throughput screening systems are automated labs for the analysis of many biochemical substances in drug discovery and virus detection process. This paper was motivated by problem automating testing viruses new drugs using high systems. The emergence severe acute respiratory syndrome coronavirus 2 (SARSCoV- 2) at turn 2019-2020 presented extraordinary challenges to public health. Existing approaches test do not use optimal schedules efficient.The scheduling activities performed various...

Abstract Ligand-modified micellar-enhanced ultrafiltration (LM-MEUF) is a membrane technique based on separation process which can be used for removal of target metals from an aqueous solution. This method involves adding both metal complexing ligand and surfactant molecule to the solution under conditions where most molecules are present as micelles. attached surface micelles by solubilization forms complexes with ion. The then treated through has smaller pore sizes than those complexes....

Background: Osteosarcoma is a malignant tumor type that starts in bone and occurs most frequently adolescents. Traditional techniques are insufficient, especially for metastatic ones. As alternative treatment techniques, natural products worthy of examining due to being safe innovative. Essential polyunsaturated fatty acids, mainly omega-3 omega-6 have various positive effects on human health growth. In addition, some PUFAs show anti-cancer activity by inducing apoptosis, specifically cancer...

Bilgi ve iletişim teknolojilerinde olağanüstü gelişim kamusal etkinliklerde de yeni teknoloji kullanımını beraberinde getirmiştir. Gelir idareleri diğer kamu gibi bu sürece dâhil olmuştur. Türk İdaresi 90’lı yılların başından itibaren hayata geçirdiği bir dizi otomasyon projesi ile uyum yönetim maliyetlerini minimize etmek üzere bilgisayar teknolojilerini birer araç olarak kullanmayı, kurumun çalışmalarında etkinlik verimliliğini arttırmayı sağladığı verilerle güçlü karar destek bilgi...

Optimum conditions for removal of Cu(II) ions from both single-component and Cd(II)-containing solutions by ligand-modified micellar-enhanced ultrafiltration (LM-MEUF) in the presence cetyltrimethylammonium bromide (CTAB) triton X-100 (TX100) micelles were determined.TX100 was not found to be effective separation LM-MEUF.The most ligand CTAB micellar media, out 20 ligands, 2,4,6-tri(2-pyridyl)-1,3,5-triazine (TPTZ) solutions.99.99% 5.0 × 10 -4 mol L -1 could provided -3 1.0 TPTZ.Complete...