A5011449190- Synthesis and biological activity
- Synthesis and Characterization of Heterocyclic Compounds
- Essential Oils and Antimicrobial Activity
- Synthesis and Biological Evaluation
- Bee Products Chemical Analysis
- Insect and Pesticide Research
- Phytochemistry and Biological Activities
- Click Chemistry and Applications
- Phytochemicals and Antioxidant Activities
- Plant and animal studies
- Multicomponent Synthesis of Heterocycles
- Natural product bioactivities and synthesis
- Plant-Microbe Interactions and Immunity
- Bioactive Compounds and Antitumor Agents
- Fungal Biology and Applications
- Cancer therapeutics and mechanisms
- Synthesis and Reactions of Organic Compounds
- Sesquiterpenes and Asteraceae Studies
- Insect and Arachnid Ecology and Behavior
- Microwave-Assisted Synthesis and Applications
- Healthcare and Venom Research
- Phenothiazines and Benzothiazines Synthesis and Activities
- Nuts composition and effects
- Mycorrhizal Fungi and Plant Interactions
- Medicinal Plants and Neuroprotection
Recep Tayyip Erdoğan University
2016-2025
Çankırı Karatekin University
2022
Pharmac
2022
ORCID
2021
Zirve University
2007-2016
Baze University
2012
Karadeniz Technical University
2004-2012
Some novel 4,5-disubstituted-2,4-dihydro-3H-1,2,4-triazol-3-one (3, 6, 8, 9) derivatives and or 3-(4-methylphenyl)[1,2,4]triazolo[3,4-b][1,3]benzoxazole (5) were synthesized from the reaction of various ester ethoxycarbonylhydrazones (1a-e) with several primary amines. The synthesis 4-amino-5-(4-chlorophenyl)-2-[(5-mercapto-1,3,4-oxadiazol-2-yl)methyl]-2,4-dihydro-3H-1,2,4-triazol-3-one (13) was performed starting 4-Amino-5-(4-chlorophenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (2) by four...
There is considerable interest in alternative approaches to inhibit Helicobacter pylori (H. pylori) and thus treat many stomach diseases. Propolis a pharmaceutical mixture containing natural bioactive substances. The aim of this study was use propolis samples H. pylori. anti-H. anti-urease activities 15 different ethanolic extracts (EPEs) were tested. total phenolic contents flavonoid the EPE also measured. agar-well diffusion assay carried out on strain J99 inhibition zones measured...
This study was planned to investigate some physicochemical and anti-inflammatory, antioxidant, antimicrobial properties of three different degrees unifloral characters chestnut honeys. Antihyaluronidase, antiurease activities were evaluated as anti-inflammatory characteristics. Total phenolic contents, flavonoids, tannins, profiles, ferric-reducing antioxidant power (FRAP), scavenging 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid (ABTS+) 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals...
2-[6-(Morpholin-4-yl)pyridin-3-ylamino]acetohydrazide (4) was obtained starting from 6-morpholin-4-ylpyridin-3-amine (2) via the formation of ester (3) and then converted to corresponding Schiff bases (5, 6) with reaction aromatic aldehydes. The carbothioamide (9), hydrazide phenylisothiocyanate, 1,2,4-triazole (11) 1,3,4-thiadiazole (12) derivatives by treatment NaOH or H2SO4, respectively. cyclocondenzation 9 4-chlorophenacyl bromide ethyl bromoacetate produced 1,3-thiazole (10)...
The essential oils of mosses [Tortula muralis Hedw. (Pottiaceae), Homalothecium lutescens (Hedw.) H. Rob. (Brachytheciaceae), Hypnum cupressiforme (Hypnaceae), and Pohlia nutans Lindb. (Mniaceae)] were investigated by means GC-FID/MS techniques. major components nonanal (18.3%) tetradecanol (4.3%) in the oil T. muralis, (36.8%) tricosane (6.5%) lutescens, (12.5%) 2E-tetradecen-1-ol (6.9%) cupressiforme, (7.8%) (7.1%) P. nutans. rich as non-terpenoid aldehydes (26.9%, 50.9%, 15.6%, 33.4%,...
This is the first report about characterization of Trichoderma harzianum lipase. A novel strain IDM14D was isolated from soil. The cultivated for lipase production in shake flasks at 30 °C 7 days. For production, it determined that best carbon source glucose and nitrogen peptone. Maximum biomass produced a concentration 1.25 g/L, optimum pH temperature activity enzyme were 8.5 40 °C, respectively. stable range 8.0-10.0 60 min. Ca^{2+} Mn^{2+} enhanced but other metallic ions did not affect...
Background/Objectives: This study aimed to develop cinnamon bark essential oil (CEO), orange peel oil(OEO) and the combination of these two oils (OEO-CEO) loaded PLGA nanoparticles prevent dental caries investigate their effectiveness in silico vitro methods. Methods: EO were produced by single emulsion method. Detailed characterization studies performed using different methods, controlled release profile was obtained. The antibacterial activity developed formulations investigated on S....
Volatile organic compounds (VOCs) of essential oils (EOs) and solid phase microextract (SPME) obtained from the flower, leaf, stem Epilobium angustifolium L. were analyzed by GC-FID/MS. The EOs SPMEs consist mainly monoterpenes aldehydes, which are major classes compounds. Limonene was found to be a compound in flower (HD: 42.9% vs. SPME: 95.5%), leaf 60.3% 4.7%), 49.06% 93.6%). antimicrobial activity solvent extracts (n-hexane, acetonitrile, methanol) E. screened vitro against nine...
Quinoline-2-carbohydrazide (2) obtained from quinaldic acid (1) was converted to the corresponding carbothioamide 3 and carboxamide 6 by treatment with benzyliso(thio)cyanate. The basic of yielded 1,2,4-triazole derivatives 4 7. synthesis 5-(quinolin-2-yl)-1,3,4- oxadiazol-2-thiol (9) performed reaction 1 CS_2 in media. Mannich compounds 4, 7, 9 resulted formation aminoalkylated 5a-c, 8, 10a,b. condensation thiosemicarbazide, carbohydrazide, or thiocarbohydrazide gave (11-13)....