Volatile organic compounds (VOCs) of essential oils (EOs) and solid phase microextract (SPME) obtained from the flower, leaf, stem Epilobium angustifolium L. were analyzed by GC-FID/MS. The EOs SPMEs consist mainly monoterpenes aldehydes, which are major classes compounds. Limonene was found to be a compound in flower (HD: 42.9% vs. SPME: 95.5%), leaf 60.3% 4.7%), 49.06% 93.6%). antimicrobial activity solvent extracts (n-hexane, acetonitrile, methanol) E. screened vitro against nine...

Volatile organic compounds (VOCs) of six coniferous tree barks (A. nordmanniana, P. brutia, orientalis, pinaster, sylvestris, C. libani) and nine deciduous (E. globulus, R. pseudoacacia, Q. pontica, A. glutinosa, sativa, F. tremula, equisetifolia dealbata) were analyzed by the solid phase micro extraction (SPME) method with gas chromatography-mass spectrometry (GC-FID/MS). The SPME-GC-FID/MS analysis revealed 96 VOCs in samples 83 samples. Monoterpene hydrocarbon components main constituent...

Phenothiazines (PTZ) are antipsychotics known to modulate a variety of neurotransmitter activities that include dopaminergic and cholinergic signaling have been identified as potential anticancer agents in vitro. However, it is important also test whether highly cytotoxic, repurposed, or novel PTZ has low toxicity neuromodulatory activity vivo using vertebrate model organisms, such zebrafish. In this study, we synthesized phenothiazines screened them vitro liver cancer zebrafish...

The aerial parts of Alchemilla L. species (Rosaceae) are used internally as diuretic, laxative, tonic and externally for wound healing in Turkish folk medicine.Antioxidant effects the extracts, fractions isolated compounds from A. barbatiflora Juz. were investigated with following methods: 1,1-diphenyl-2-picryl-hydrazyl (DPPH), superoxide radical scavenging (SOD), phosphomolibdenum-reducing antioxidant power (PRAP), ferric-reducing (FRAP) assays.In addition, tyrosinase, α-glucosidase...

A solid phase microextraction (SPME) method with gas chromatography-mass spectrometry (GC-MS) was used for analyses of the volatile compounds six Geranium species; G. asphodeloides, psilostemon, purpureum, pyrenaicum, robertianum and sanguineum. The results were compared those obtained by hydrodistillation. According to study, major identified in SPME extracts sabinen (33.5%) (G. asphodeloides), caryophyllene (34.1%, 21.7%, 11.2%) purpureum robertianum), germacrene D (25.2%) pyrenaicum),...

Sortase A (SrtA) is an attractive target for developing new anti-infective drugs that aim to interfere with essential virulence mechanisms, such as adhesion host cells and biofilm formation. Herein, twenty hydroxy, nitro, bromo, fluoro, methoxy substituted chalcone compounds were synthesized, antimicrobial activities molecular modeling strategies against the SrtA enzyme investigated. The most active found be T2, T4, T19 Streptococcus mutans (S. mutans) MIC values of 1.93, 3.8, 3.94 μg/mL,...

Abstract Background Aboveground parts and bulbs of Ornithogalum species are consumed as food used in traditional medicine worldwide. Objective It is aimed to report the antioxidant capacity phenolic compounds content sigmoideum , orthophyllum oligophyllum for first time. Materials methods Antioxidant activity crude methanol extracts aerial were determined with 1,1-diphenyl-2-picryl-hydrazyl, superoxide radical scavenging, ferrous ion-chelating effect, phosphomolybdenum-reducing power...

Volatile compounds of three Stachys species; macrantha (C. Koch) Stearn, sylvatica L. and annua ssp. var. were analyzed by a solid phase micro extraction (SPME) method coupled with gas chromatographyflame ionization detector (GC–FID) chromatographymass spectrometry (GC-MS). A total 38 (99.2%), 39 (99.0%) 33 (98.8%) volatile identified from S. annua, respectively. The major constituents the investigated species were; α-pinene (11.2%), p-cymene (18.2%), carvacrol (28.8%) in macrantha,...

Aims: This work was designed to evaluate the antimicrobial activity of three different commercial herbal (Aloe vera L. and Fragaria vesca extracts) toothpastes [LR Aloe (HTP1), ESI fresh (HTP2) ROCS Teens (HTP3)] against two microorganisms that cause tooth infections. Materials Methods: An agar disk diffusion method used test gel in amount 100 μL Streptococcus mutans Staphylococcus aureus. In second part work, volatile organic compounds (HTP1-3) were determined by solid-phase...

In the present study, volatile composition of Ulva rigida (U. rigida) was elucidated by two different methods. As a result identification process components using GC/MS-FID instrument, 31 compounds were identified hydrodistillation (HD) method, and 15 solid-phase microextraction (SPME) elucidating structure 99.86 % 92.65 %, respectively. The most abundant in essential oil U. n-hexadecanoic acid pentadecanal, while compound according to SPME analysis heptadecyne, hydrocarbon compound. next...

The essential oils of the five Scrophularia species; chrysantha Jaub.et Spach, kotschyana Benth., olympica Boiss., cinerascens Boiss.and zuvandica Grossh.were obtained by hydrodistillation (HD) with a range 0.10% to 0.16% yield and analazsed GC-FID/MS.In meantime, volatile organic compounds (VOCs) S. chrysantha, kotschyana, olympica, were also identified technique SPME GC-FID/MS phytochemical results evaluated.The experimental this study showed that major which taken carvacrol (52.4%),...

Amaç: Crataegus türleri gıda olarak ve halk arasında çeşitli hastalıkların tedavisinde kullanılmaktadır.Bu çalışma Türkiye'den toplanan microphylla C. Koch'tan hazırlanan farklı ekstraktların biyolojik özelliklerini araştırmayı amaçlamaktadır.Gereç Yöntemler: Kurutulmuş yaprak, gövde kabuğu taze meyve örnekleri ayrıldı etanol ekstresi, asitlendirilmiş (%0.5 HCl, pH: 2.5) etanol:su (1:1) metanol HCI, metanol:su su ekstresi hazırlandı.Ekstrelerin oksidatif DNA hasarının önlenmesi,...

This research aimed to investigate the effect of different extraction methods and chemical composition essential oil (EO) solid-phase microextraction (SPME) from Campanula latifolia L. sub-sp. which is native Turkey, with medicinal properties. Phenolic components, antioxidant enzyme inhibitory effects (EO), n-hexane, acetonitrile, methanol water extracts C. subsp. were also studied. The volatile components EO, SPME n-hexane extracts, obtained latifolia, analyzed by GC-FID/MS. A total 32, 31...

Volatile compositions of the hydrodistillated essential oils (EOs), SPME and hexane extracts from stems, leaves roots Sarcopoterium spinosum (L.) Spach. were investigated by means GC GC-MS. Vegetative organs found to contain different volatile compounds. Oxygenated monoterpenes (20.7 %), aromatic compounds (33.0 %) aldehydes (39.6 identified as main components in EO stems. sesquiterpenes (25.7 aliphatic hydrocarbons (21.2 (42.5 high percentages leaves, while (48.4 (51.6 be major constituent...

The volatile organic compounds (VOCs) of two Coronilla species (Coronilla orientalis Miller and varia L.) obtained by hydrodistillation (HD) solid phase microextraction (SPME) techniques were identified GC-FID/MS. major in the SPME extracts limonene (43.4%) (C. orientalis),(Z)-β-ocimene (E)-β-ocimene (34.3% 32.4%) varia), whereas, essential oils C. rich with γ-terpinene (22.4%) phytol (30.7%), respectively. In addition, acetylcholinesterase (AChE), butyrylcholinesterase (BuChE), tyrosinase,...

TThe essential oil (EO), solid phase micro extraction (SPME), and SPME of n-hexane extract Epilobium hirsutum L. were analyzed by GC-FID/MS. A total 35, 20, 32 compounds identified from E. hirsutum, accounting for 98.2% in HD, 97.6% SPME, 98.8% extract, respectively. The EO consisted mainly alcohol (HD: 51.5% vs. SPME: 30.8%). Aromatic hydrocarbons (57.1%) was the major extract. Monoterpenes minor constituents (2.3%) (3.1%) hirsutum. (Z)-3-Hexene-1-ol (46.5%), (Z)-3-hexenyl acetate (18.2%),...

Phytochemical analysis of two endemic Scorzonera pisidica Hub.-Mor.and sandrasica Hartvig & Strid species have not been mentioned before.In this work, volatile organic compounds, phenolic contents, antimicrobial, and tyrosinase inhibition activities S. grown in Turkey were investigated.Aldehydes the primary chemical class for compounds essential oils (EOs, 49.5%, 44.9%) SPME (85.8% 56.9%) sandrasica, aromatic main n-hexane extracts (86.9%) (86.3%), respectively.The constituent methanol...

Volatile compounds of three Stachys species; macrantha (C. Koch) Stearn , sylvatica L. and annua ssp. var. were analyzed by a solid phase micro extraction (SPME) method with gas chromatography-mass spectrometry (GC-MS). A total 38 (99.2%), (99.0%) 32 (98.8%) volatile identified different constituents from S. annua, respectively. The major the investigated species were; α -pinene (11.2%), p -cymene (18.2%), carvacrol (28.8%) in γ -muurolene (10.2%), -cedrene limonene (37.0%) (11,4%), β...

The essential oil (EO) and phenolic constituents of Parentucellia viscosa L. were analyzed by GC-FID-MS HPLC, respectively. A total 20 volatile compounds identified accounting for 99.97% in hydrodistillation. Monoterpenes (50.57%, 5 compounds) the primary chemical class P. viscosa. Limonene (44.02%) 1-octen-3-ol (25.23%) major components constituent analysis methanol extract gave benzoic acid (0.97 mg/g) as compound. antimicrobial activities EO crude solvent (n-hexane, acetonitrile,...

The present study was undertaken to evaluate the in vivo analgesic activities of extracts prepared from aerial parts and roots Scrophularia kotscyhana isolate bioactive metabolites most active extract. Analgesic all subextracts at doses 5, 10 30 mg/kg (i.p.) were examined using hot plate test mice. Among tested extracts, MeOH extract n-butanol subextract thereof displayed best activity doses. Phytochemical studies on led isolation two new iridoid glycosides as an inseparable mixture,...

Five new phenyl dihydroisocoumarin glycosides (1-5) and two known compounds (6-7) were identified from the butanol fraction of Scorzonera longiana. The structures 1-7 elucidated based on spectroscopic methods. Antimicrobial, antitubercular, antifungal evaluation carried out using microdilution method against nine microorganisms. Compound 1 was active only Mycobacterium smegmatis (Ms) with a MIC value 14.84 μg/mL. All tested (1-7) Ms but 3-7 fungi (C. albicans, S. cerevisiae) values 25.0-125...

Two new dihydroisocoumarins (scorzolongin I (1), and scorzolongin II (2)) nine known compounds (3′,5′-dimethoxy hydrangenol III, 3), cladantholide (4), dammar-24-ene-3β-ol (5), taraxasterol (6), β-sitosterol (7), mangifgerursanone (8), a mixture of α-amyrenone (9a), β-amyrenone (9b), dammar-24-ene-3-one (9c) in about 1:1:2 ratio) were identified from the dichloromethane fraction Scorzonera longiana. The structure all (1–9a–c) elucidated by extensive 1D 2D NMR (1H, 13C/APT, COSY, HMBC, HSQC,...

Volatile organic compositions of the essential oils (EOs), solid-phase microextraction (SPME) and SPME n-hexane extracts from flower stem-leaf Filipendula vulgaris (F. vulgaris) were analyzed by GC-FID/MS. A total 107 constituents characterized, parts plant found to contain different volatile compounds. Tricosane (29.6%), n-nonanal (20.5%) identified as main components in oil flower, while phytol (35.2%) was be a major constituent stem-leaf. Benzaldehyde (56.0%) (31.6%) groups respectively....