A5037486400- Phytochemistry and Biological Activities
- Essential Oils and Antimicrobial Activity
- Phytochemicals and Antioxidant Activities
- Natural product bioactivities and synthesis
- Dental materials and restorations
- Traditional Chinese Medicine Analysis
- Medicinal plant effects and applications
- Plant Gene Expression Analysis
- Bee Products Chemical Analysis
- Botanical Research and Applications
- Drug-Induced Hepatotoxicity and Protection
- Tannin, Tannase and Anticancer Activities
- Pharmacological Effects of Natural Compounds
- Analytical Chemistry and Chromatography
- Nanoparticles: synthesis and applications
- Biofuel production and bioconversion
- Orthodontics and Dentofacial Orthopedics
- Antibiotic Resistance in Bacteria
- Plant Pathogens and Fungal Diseases
- Dental Health and Care Utilization
- Photopolymerization techniques and applications
- Nanotechnology research and applications
- Allelopathy and phytotoxic interactions
- Plant biochemistry and biosynthesis
- Fullerene Chemistry and Applications
Recep Tayyip Erdoğan University
2013-2024
Karadeniz Technical University
2024
Joint BioEnergy Institute
2023-2024
Lawrence Berkeley National Laboratory
2023-2024
Ministry of Food Agriculture and Livestock
2023
Organic acids of primary metabolism are essential for energy metabolism. They can range from formate (C1), glyoxylate (C2), to citrate (C6), or greater. While reversed phase (RP) C18 chromatography may not be the ideal separation technique these acids, due their polar nature, use mixed-mode RP stationary phases provide retention through hydrogen bonding and other interactions. To this end, we have developed a RP-QTOF-MS method (via Sulpeco Ascentis Express RP-Amide column) capable...
Organic acids of primary metabolism are essential for energy metabolism. They can range from formate (C1), glyoxylate (C2), to citrate (C6), or greater. While reversed phase (RP) C18 chromatography may not be the ideal separation technique these acids, due their polar nature, use mixed-mode RP stationary phases provide retention through hydrogen bonding and other interactions. To this end, we have developed a RP-QTOF-MS method (via Sulpeco Ascentis Express RP-Amide column) capable...
Synthetic biology tools have accelerated the generation of simple mutants, but combinatorial testing remains a major hurdle. High-throughput methods struggle translating from proof-of-principle molecules to advanced bioproducts. We address this challenge with biosensor-driven strategy for enhanced isoprenol production in Pseudomonas putida , key precursor sustainable aviation fuel and platform chemicals. This biosensor leverages P. putida's native response short-chain alcohols via previously...
Nanotechnology in agricultural applications is promising improving plant nutrition and yield, pest control, gene delivery. However, the method to synthesize nanoparticles or nanocomposites (NCs) can play a crucial role determining characteristics of NCs, such as size morphology, which may be critical factors affecting NCs` potential toxicity. This study elucidates effect sonication time synthesizing NCs on its use efficiency. For this purpose, hard/soft nanocomposite (NC)...
"Mad honey" is a complex mixture of numerous chemicals produced by honeybees from Rhododendron flowers. Consumption mad honey leads to diarrhea, perspiration, dizziness, changes in consciousness, syncope, diplopia, as well blurred vision, hypotension, and bradycardia due the presence grayanotoxins (GTXs). Therefore, it important detect level honey. Besides its toxicity, also has antioxidant activity. This study was designed determine grayanotoxin-III toxin activity ten different samples...
Plant-derived antioxidant compounds have the potential to prevent cell damage caused by free radicals. As a holoparasitic plant, Cuscuta campestris Yuncker is being valorized for treatment of liver injury and cancer prevention in traditional medicine. The main purpose this present study elucidate antioxidant- anticancer-associated contents C. spectroscopic chromatographic methods. Diethyl ether, ethyl acetate, methanol, n-butanol, water were used as extraction solvents reach wide range...
Doxorubicin (DOX) is an anthracycline cancer chemotherapeutic that exhibits cumulative dose-limiting cardiotoxicity and limits its clinical utility. DOX treatment results in the development of morbid cardiac hypertrophy progresses to congestive heart failure death. Recent evidence suggests during mediated hypertrophy, mitochondrial energetics are severely compromised, thus priming cardiomyocyte for failure. To mitigate dose (5 mg/kg, QIW x 4 weeks with 2 recovery) dependent DOX, we applied...
Investigation of novel plant-based agents might provide alternative antibiotics and thus fight antibiotic resistance. Here, we measured the ability fruit leaf extracts Sorbus aucuparia (Sauc) endemic caucasica var. yaltirikii (Scau) to inhibit nonreplicative (Klenow Fragment-KF Bacillus Large Fragment-BLF) replicative (DnaE PolC) bacterial DNA polymerases along with their antimicrobial, DPPH free radical scavenging activity (RSA), chemical contents by total phenolic content HPLC-DAD...
Objectives: This in vitro study assessed the effect of different light-curing units on elution monomers from bulk fill composites with thicknesses. Methods: Five (Filtek Bulk Fill Flowable, SonicFill 2, SDR, Tetric N-Ceram Fill, and Venus Fill) one conventional composite Z250) were selected for study. The cylindrical specimens thickness 2 mm or 4 prepared photopolymerized 20 s a light-emitting diode (VALO Cordless) halogen (Monitex BlueLuxer) unit. glass vials covered 75% ethanol/water...
Purpose: To investigate the effects of EtOAc extract U. longissima which is uninvestigated previously on esophagogastric cancer induced in rats with N-methyl-N-nitro-N-nitrosoguanidin (MNNG). Methods: The anticancer activity was examined adenocarcinoma models MNNG. longissima, 50 and 100 mg/kg oral doses were administered once daily for six months. MNNG differentiated undifferentiated type adenocarcinomas esophageal gastric tissues rats. Results: obtained from prevented cancerogenesis did...
Abstract Modification of lignin in feedstocks via genetic engineering aims to reduce biomass recalcitrance facilitate efficient conversion processes. These improvements can be achieved by expressing exogenous enzymes that interfere with native biosynthetic pathways responsible for the production precursors. In planta expression a bacterial 3-dehydroshikimate dehydratase poplar trees reduced content and altered monomer composition, which enabled higher yields sugars after cell wall...
Abstract Background Aboveground parts and bulbs of Ornithogalum species are consumed as food used in traditional medicine worldwide. Objective It is aimed to report the antioxidant capacity phenolic compounds content sigmoideum , orthophyllum oligophyllum for first time. Materials methods Antioxidant activity crude methanol extracts aerial were determined with 1,1-diphenyl-2-picryl-hydrazyl, superoxide radical scavenging, ferrous ion-chelating effect, phosphomolybdenum-reducing power...
Phlomis linearis Boiss. & Bal. of the Lamiaceae family is one endemic species in Turkey, i.e., growing east, central, and southeast parts Anatolia used for herbal tea. This study was designed to identify biochemical bioactivity properties this by DPPH scavenging activity, metal chelating total phenolic content, HPLC-DAD analysis, MTT assay. Furthermore, plant extract evaluated its antimicrobial activity against bacteria fungi using microdilution method. The interactions between plasmid DNA...
The goal of this study was to examine the effect thermal cycling on amount monomer released from bulk fill composites. Five composite resins were used in study. Extraction solutions obtained at end time/thermal cycle periods: 0-1 day/0-1,500, 1-3 days/1,500-4,500 and 3-7 days/4,500-10,000. monomers extractions samples taken each time point measured an HPLC instrument. data analyzed by repeated measures variance analysis tukey multiple comparison tests (p<0.05). thermocycling increased all...
Color stabilities of experimental composite resins based on Bis-EFMA (a novel bisphenol A [BPA]-free monomer system) with 3M ESPE FiltekTM Z250 (FZ) and A-glycidyl methacrylate (Bis-GMA) urethane dimethacrylate (UDMA) were compared. was synthesized via the reaction between 9,9-bis[4-(2-hydroxyethoxy)phenyl]fluorene 2-(methacryloyloxy)ethyl isocyanate. Experimental Bis-EFMA-, Bis-GMA-, UMDA-based composites prepared (20% each Bis-EFMA, Bis-GMA, UDMA, or triethylene glycol (TEGDMA) 60% glass...
Abstract The study aimed to analyze antibiotic resistance determinants in a carbapenem-resistant Klebsiella pneumoniae by whole-genome sequencing (WGS). K. was isolated from urine sample and it characterized 16S rDNA Turkey. This strain named as Kpn Rize-53-TR. Antimicrobial susceptibility testing performed for seventeen antibiotics VITEK-2 the result confirmed MIC. whole genome of isolate sequenced Illumina analysed bioinformatic tools MLST, replicon types, antimicrobial genes. data...
Abstract This study aimed to compare the monomer elution, microhardness, and roughness of experimental resin‐based composites (RBCs) prepared from a novel system derived 9,9‐Bis[4‐(2‐hydroxyethoxy)phenyl]fluorene) (Bis‐EFMA), bisphenol A‐glycidyl methacrylate (Bis‐GMA), urethane dimethacrylate (UDMA) with each other, also commercial RBC, 3 M ESPE FiltekTM Z250 (FZ). Experimental Bis‐EFMA (ET), Bis‐GMA (BT), UDMA (UT) based were (20% or 20% UDMA, triethylene glycol [TEGDMA], 60% glass...