A5051270823- Essential Oils and Antimicrobial Activity
- Synthesis and biological activity
- Phytochemistry and Biological Activities
- Natural product bioactivities and synthesis
- Synthesis and Characterization of Heterocyclic Compounds
- Occupational Health and Safety Research
- Synthesis and Reactions of Organic Compounds
- Multicomponent Synthesis of Heterocycles
- Porphyrin and Phthalocyanine Chemistry
- Synthesis and Biological Evaluation
- Synthesis of Organic Compounds
- Risk and Safety Analysis
- Photochemistry and Electron Transfer Studies
- Bee Products Chemical Analysis
- Computational Drug Discovery Methods
- Ethnobotanical and Medicinal Plants Studies
- Photodynamic Therapy Research Studies
- Sesquiterpenes and Asteraceae Studies
- Healthcare and Environmental Waste Management
- melanin and skin pigmentation
- Occupational and environmental lung diseases
- Natural Antidiabetic Agents Studies
- Healthcare Facilities Design and Sustainability
- Workplace Violence and Bullying
- Quinazolinone synthesis and applications
Artvin Coruh University
2024
Avrasya University
2018-2023
Karadeniz Technical University
2012-2023
Asia University
2020
In this study, new Schiff base compounds (SB-F-OH, SB-Cl-OH and SB-Br-OH) were derived from chalcone-derived amine containing halogen groups 4-hydroxybenzaldehyde. Also, their phthalonitrile (SB-F-CN, SB-Cl-CN SB-Br-CN) have been synthesized. The structures of these elucidated by NMR, FT-IR Mass spectroscopic methods. quantum chemical parameters calculated at B3LYP/6–31++g(d,p), HF/6–31++g(d,p) M062X/6–31++g(d,p) levels. As the biological application synthesized compounds, (i) inhibition...
Yararlı işlerin devamı için ateşin dikkatli kullanımı gerekir. Kontrol altına alınamayan ateş, yangına dönüşerek ciddi felaketlere yol açmaktadır. Bu felaketlerin birçoğu yanma sebebi ile meydana gelen zehirleyici duman ve gazların solunması maddi hasarlar oluşmaktadır. Yangınlar birçok sebepten gelmektedir. Ülkemizde yapılan çalışmalar, elektrik kaynaklı yangınların ilk üç sırada yer aldığını göstermektedir. çalışmada; halk eğitim kurumuna ait derslik sınıflarda var olan tehlikelerin...
Twenty-five new hydroxy- and methoxy-substituted 4,6-diarylpyrimidin-2(1H)-ol (20-34) 4,6-diarylpyri\-midine-2(1H)-thiol derivatives (35-44) were synthesized from the reaction of corresponding 1,3-diaryl-2-propene-1-one compounds (1-19) with urea or thiourea using solid-phase microwave method. All synthetic (20-44) evaluated regard to their $\alpha $-glucosidase activity. However, only 22-25, 27,31,34, 35,37, 40 exhibited a greater inhibitory effect than standard acarbose. The IC$_{50}$...
In the present study, volatile composition of Ulva rigida (U. rigida) was elucidated by two different methods. As a result identification process components using GC/MS-FID instrument, 31 compounds were identified hydrodistillation (HD) method, and 15 solid-phase microextraction (SPME) elucidating structure 99.86 % 92.65 %, respectively. The most abundant in essential oil U. n-hexadecanoic acid pentadecanal, while compound according to SPME analysis heptadecyne, hydrocarbon compound. next...
This research aimed to investigate the effect of different extraction methods and chemical composition essential oil (EO) solid-phase microextraction (SPME) from Campanula latifolia L. sub-sp. which is native Turkey, with medicinal properties. Phenolic components, antioxidant enzyme inhibitory effects (EO), n-hexane, acetonitrile, methanol water extracts C. subsp. were also studied. The volatile components EO, SPME n-hexane extracts, obtained latifolia, analyzed by GC-FID/MS. A total 32, 31...
Ethyl[4-arylmethyleneamino-3-(4-metylphenyl)-5-oxo-4,5-dihydro- 1H-1,2,4-triazole-1-yl]acetates (3a-e and 10a-d) were obtained starting from 4-amino-2,4-dihydro-3H-1,2,4-triazol-3-ones (1 9) in 2 steps. The treatment of 3a-e with NaBH_4 resulted the formation 3 kinds product incorporating carboxcilic acid (4a-c) or alcohol (5a-e) functionality. [4-{[(4-Methoxyphenyl)methylene]amino}- 4-{[pyridin-4-ylmethylene]amino}-3-(4-methylphenyl)-5-oxo-4,5-dihydro-1H- 1,2,4-triazole-1-yl] acetic acids...
Volatile constituents of the essential oil which was obtained by hydrodistillation (HD) in a Clevengertype apparatus from air-dried Salvia staminea Montbret & Aucher ex Bentham (Lamiaceae) collected Bayburt (North East Part Black Sea Reagan Turkey), were analyzed GC-FID and GC-MS.Additionally, volatiles for whole part S. two different methods are headspace (HS)-GC-FID/MS solid-phase micro extraction (HS-SPME)-GC-FID/MS.As results this study, thirty compounds hydrodistillation, fifteen...
Volatile compositions of the hydrodistillated essential oils (EOs), SPME and hexane extracts from stems, leaves roots Sarcopoterium spinosum (L.) Spach. were investigated by means GC GC-MS. Vegetative organs found to contain different volatile compounds. Oxygenated monoterpenes (20.7 %), aromatic compounds (33.0 %) aldehydes (39.6 identified as main components in EO stems. sesquiterpenes (25.7 aliphatic hydrocarbons (21.2 (42.5 high percentages leaves, while (48.4 (51.6 be major constituent...
A series of eleven hydroxy and methoxy by the condensation chalcone (1asynthesized compounds were characterized using NMR (1D; ROESY), FT-IR, UV, LC-MS spectral data elemental analysis.These synthetic ( screened for their α-glucosidase inhibition.Th 2a 2b with in range 1.61 (IC 50 , 13,34 µM).IC values other synthesized which more or as active acarbose, but, IC geometric isomers 2a-2k showed that cisoid 1E,2E is most stable geometrical isomer all.
TThe essential oil (EO), solid phase micro extraction (SPME), and SPME of n-hexane extract Epilobium hirsutum L. were analyzed by GC-FID/MS. A total 35, 20, 32 compounds identified from E. hirsutum, accounting for 98.2% in HD, 97.6% SPME, 98.8% extract, respectively. The EO consisted mainly alcohol (HD: 51.5% vs. SPME: 30.8%). Aromatic hydrocarbons (57.1%) was the major extract. Monoterpenes minor constituents (2.3%) (3.1%) hirsutum. (Z)-3-Hexene-1-ol (46.5%), (Z)-3-hexenyl acetate (18.2%),...
Eğitim sektörü, örgün ve yaygın eğitim olarak iş sağlığı güvenliği açısından incelendiğinde risklerden etkilenen en yüksek insan popülasyonuna sahip sektör karşımıza çıkmaktadır. İnsan sayısının fazla olması yanında İşyeri büyüklüğü de bina eklentileri olan sektördür. Milli Bakanlığı (MEB) Yükseköğretim Kurumu (YÖK) verilerine göre kurumları az tehlikeli çıksa da çalışanların öğrencilerin güvenli sağlıklı olmaları için çalışmaları oldukça önemlidir. Böyle olmasına rağmen öğrenciler kurumu...
Phytochemical analysis of two endemic Scorzonera pisidica Hub.-Mor.and sandrasica Hartvig & Strid species have not been mentioned before.In this work, volatile organic compounds, phenolic contents, antimicrobial, and tyrosinase inhibition activities S. grown in Turkey were investigated.Aldehydes the primary chemical class for compounds essential oils (EOs, 49.5%, 44.9%) SPME (85.8% 56.9%) sandrasica, aromatic main n-hexane extracts (86.9%) (86.3%), respectively.The constituent methanol...
Introduction: The aim of this study was to specify the antioxidant and antimicrobial activity synthesized 2-amino substituted halochalcone N-glycoside derivative compounds. Methods: capacity compounds (1-4) determined by cupric ion reducing (CUPRAC), ferric power (FRAP). Antimicrobial on 9 microorganism agar well diffusion method.Results: According results, compound 3 showed highest activity. against Yersinia pseudotuberculosis, Pseudomonas aeruginosa, Candida albicans while 4 Escherichia...
In the presented study, a series of methoxylated pyrazoline compounds containing amine (Py1-NH2 and Py2-NH2), tosyl (Py1-Ts Py2-Ts), nitrile (Py1-CN Py2-CN) group were synthesized The structures these clarified (by MS, FT-IR, NMR analysis) through use mass spectral (spectrometer), FT-IR (spectrophotometer), (spectrometer) data. order to examine chemical properties derivatives theoretically, calculations performed on B3LYP, HF, M06-2x methods using 6-31++g(d,p) basis set. addition, molecular...
The essential oil (EO) and phenolic constituents of Parentucellia viscosa L. were analyzed by GC-FID-MS HPLC, respectively. A total 20 volatile compounds identified accounting for 99.97% in hydrodistillation. Monoterpenes (50.57%, 5 compounds) the primary chemical class P. viscosa. Limonene (44.02%) 1-octen-3-ol (25.23%) major components constituent analysis methanol extract gave benzoic acid (0.97 mg/g) as compound. antimicrobial activities EO crude solvent (n-hexane, acetonitrile,...
A simple, rapid, sensitive, and low-cost spectrofluorometric method was developed for the determination of Au(III) using 5-(2,3-dimethoxyphenyl)-3-(4-methoxyphenyl)-1-phenyl-4,5-dihydro-1H-pyrazole (L) in ethanol/water. The is based on change fluorescence intensity at 464 nm after excitation 355 as a result reaction between ligand Au(III). fluorescent emission decreased with increasing concentration. concentration, pH effect, response time, effect foreign ions were determined. From results...
The aim of this research was to investigate the effect different extraction methods and chemical composition essential oil solid-phase microextraction (SPME) from Rhododendrum caucasium Pall.The volatiles R. caucasicum have been isolated by hydro distillation (HD) SPME.The compositions were characterized GC-FID/MS.A total twenty-five thirty-one compounds identified constituting over 89.25%, 90.33% obtained with HD SPME, respectively.The main volatile constituents found be calarene (46.13%...
Volatile organic compositions of the essential oils (EOs), solid-phase microextraction (SPME) and SPME n-hexane extracts from flower stem-leaf Filipendula vulgaris (F. vulgaris) were analyzed by GC-FID/MS. A total 107 constituents characterized, parts plant found to contain different volatile compounds. Tricosane (29.6%), n-nonanal (20.5%) identified as main components in oil flower, while phytol (35.2%) was be a major constituent stem-leaf. Benzaldehyde (56.0%) (31.6%) groups respectively....