Propolis has highly biologically active natural substances. is rich in phenolic compounds, and becoming increasingly popular because of its components' potential role contributing to human health. Its composition variable depends on several factors. In this study, some individual compounds were analyzed investigated vitro biological activities ten different Turkish propolis samples. Seventeen constituents measured by reverse phase-high performance liquid chromatography. Total ferric reducing...

Bee pollen has been used as an apitherapy agent for several centuries to treat burns, wounds, gastrointestinal disorders, and various other diseases. The aim of our study was investigate the hepatoprotective effects chestnut bee against carbon tetrachloride (CCI4)-induced liver damage. Total phenolic content, flavonoid, ferric reducing/antioxidant power, DPPH radical activity measurements were antioxidant capacity determinants pollen. conducted in rats seven groups. Two different...

Our objective was to identify the antioxidant properties of honeybee products from Turkey, chestnut honey, pollen, propolis, and royal jelly, their hepatoprotective activity against CCl4-induced hepatic damage in rats.Animals were fed with for 7 days following CCl4 injection. Development liver oxidative stress monitored by measuring activities enzymes alanine transaminase, aspartate malondialdehyde, superoxide dismutase, catalase. Antioxidant capacities bee identified using FRAP DPPH assays,...

Chemical and biochemical properties of standard, hybrid, grafted melons cultivated under the same agricultural conditions in adjacent fields Cumra region Turkey were investigated compared based on pH, Brix, antioxidant activity, total phenolics, ascorbic acid, individual sugar, organic acid values. Seventeen different phenolic constituents quantified by reverse phase high-performance liquid chromatography (RP-HPLC). The highest variability content detected standard melon. Sugar compositions...

Three different honey extracts from the endemic plant in Black Sea region Rhododendron ponticum, were investigated for their inhibitory effects against metalloenzyme carbonic anhydrase (CA, EC 4.2.1.1), more precisely human (h) isoforms hCA I and II. Hexane, methanol, ethanol, water solid-phase extractions (SPEs) showed activity towards two CA isozymes which related to total phenolic content. The highest (0.036–0.039 mg/mL) those of propolis methanolic extract. Among three samples here,...

Abstract Objectives To determine of antioxidant, cytotoxic and tyrosinase inhibitory (TI) activities, phenolic profiles with a new high performance liquid chromatography (HPLC) method green, white black teas. Methods Antioxidant activities the teas were examined by means scavenging free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH), ferric reducing antioxidant power (FRAP), cupric capacity (CUPRAC). The contents investigated HPLC. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide...

In this study, hydroxy benzoin ( 1-7 ), benzil 8-14 and benzoin/benzil-O-β-D-glucosides 15-25 ) were synthesized to investigate their biological activities. An efficient method for synthesizing compounds 1 - 7 was prepared from four different benzaldehydes using an ultrasonic bath. Then, antioxidant (FRAP, CUPRAC, DPPH), antimicrobial (3 Gram (-), 4/6 (+), one tuberculosis fungus), enzyme inhibition (acetylcholinesterase, butyrylcholine esterase, tyrosinase, α-amylase, α- glucosidase) the...

Introduction: The aim of this study was to specify the antioxidant, antimicrobial activity and phenolic contents Ornithogalum pyrenaicum. Methods: antioxidant capacity O. pyrenaicum determined by 2,2-diphenylpicrylhydrazyl (DPPH) method ferric reduction power FRAP method. total content (TPC) samples using spectrophotometric were analyzed reverse phase-high performance liquid chromatography (RP-HPLC). Antimicrobial researched on 9 microorganism agar diffusion Results: As a result study, high...

Journal of Pharmaceutical Research International (ISSN: 2456-9119) is dedicated to publish high quality papers in all areas pharmaceutical Science including drugs, community pharmacy, hospital clinical compounding consultant internet veterinary nuclear military pharmacy informatics, pharmaceutics, medicinal chemistry, pharmacognosy, pharmacotherapy, pharmacodynamics, pharmacokinetics, pharmacology, neuropharmacology, psychopharmacology, pharmacogenetics, pharmacogenomics,...

Obesity is a risk factor for metabolic disorders causes serious health problems and economic costs globally. Some Cirsium genus has been reported to possess anti-obesity effect traditional uses vascular diseases, anti-inflammatory diuretic effects. This study aims investigate the therapeutic value of endemic species obesity treatment. C. balikesirense Yıldız, Arabacı & Dirmenci (CB), nerimaniae (CN) sommieri Petr. (CS) were selected study. High-fat diet (HFD) induced obese Sprague Dawley...

PROBLEM The aim of this study was to investigate the presence anti-carbonic anhydrase II antibodies (anti-CA II) in pre-eclampsia and relationships between autoantibodies, total antioxidant capacity (TAC) oxidant (TOC), malondialdehyde (MDA) oxidative stres index (OSI) parameters. METHOD OF STUDY We studied 40 early late onset pre-eclamptic patients healthy pregnant control 39 non-pregnant subjects. Serum CA antibodies, TAC TOC, MDA parameters were by ELISA. RESULTS mean values for TAC, OSI,...

This study describes the constituents of phenolic acids, volatile components, antioxidant and antimicrobial activities Teucrium orientale var. glabrescens. Antioxidant activity methanolic aquous extracts were examined by three different methods, namely ferric reducing power, cupric capacity 2,2-diphenylpicrylhydrazyl radical scavenging activity. The also determined reverse phase-high performance liquid chromatography. Solid phase microextraction glabrescens was analyzed Gas...

Primula vulgaris , cinsine mensup bir bitki olup, bu bitkiler sıklıkla geleneksel tedavide kullanılmaktadırlar. Farklı türlerinin farklı ekstraktlarının antioksidan ve sitotoksik etkilerini konu alan çok sayıda çalışma olmasına rağmen, P. özellikleri ile ilgili sınırlı bulunmaktadır. Bu çalışmanın amacı yapraklarının dimetil sülfoksitli ekstraktının özelliklerinin etkilerinin belirlenmesidir. Ekstraktın toplam fenolik madde miktarı, flavonoid miktarı indirgeyici güç tayini spektrofotometrik...

Abstract Background The aim of this study was to explore effects erythropoietin and pentoxifylline in tacrolimus‐induced pancreatic beta cell renal injury rats. Methods Rats group I were given saline; rats II injected with tacrolimus; III received ( E po) while IV P tx) plus tacrolimus for nine d. On 10th day, blood tissue samples taken biochemical pathological evaluations. Results Tacrolimus‐injected animals exhibited significant elevation urea nitrogen BUN ), serum levels improved...

The goal of our study was to examine antioxidant, antimicrobial, anticholinesterase activities, and phenolic composition Psephellus huber-morathii. antioxidant activities extracts have been assessed by Ferric reducing power (FRAP), cupric capacity (CUPRAC), 2,2-diphenylpicrylhydrazyl (DPPH) radical scavenging. Phenolic constituents were measured using reverse phase-high performance liquid chromatography (RP-HPLC), antimicrobial activity investigated the agar well diffusion method. Total...

The effect of peroxynitrite (PN), a highly toxic agent, on catalase (CAT) activity in fish liver microsomal homogenates was determined. PN synthesized by mixing acidic hydrogen peroxide solution with sodium nitrite and then adding hydroxide into the mixture order to stabilize labile compound peroxynitrous acid (ONOOH) anion form (ONOO(- )). decomposed (DPN), prepared preincubation HCl, monitored using constant amount homogenate containing CAT enzyme. Significant losses were observed enzyme...

Psoriasis is a chronic inflammatory skin disease characterized by relapsing episodic attacks. It also associated with an increased prevalence of diabetes mellitus, hyperlipoproteinemia, hyperuricemia, and occlusive vascular involvement.¹During different phases the disease, many cytokines other mediators derived from cells, including macrophages T lymphocytes, are released.²The secretion rate those depends on severity duration cells. These events may be one factors...

The research aimed to analyze the volatile compounds by using SPME-GC-MS and detect anticholinesterase, antityrosinase, antimicrobial potential of metanol extract Alceacalvertii Boiss., an endemic species for Türkiye. inhibitory effects tyrosinase, acetylcholinesterase, butyrylcholinesterase plant were determined spectroscopic technique plant’s activity was assessed agar diffusion method. A total 18 specified belonging terpenes classes. o-cymene (10.60%) sesquicineole (15.55%) detected as...