A5034207500- Dermatological and Skeletal Disorders
- Autoimmune Bullous Skin Diseases
- Skin and Cellular Biology Research
- Cellular Mechanics and Interactions
- CAR-T cell therapy research
- Cutaneous lymphoproliferative disorders research
- Urticaria and Related Conditions
- Nonmelanoma Skin Cancer Studies
- Sympathectomy and Hyperhidrosis Treatments
- Diagnosis and Treatment of Venous Diseases
- Chronic Lymphocytic Leukemia Research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Diabetic Foot Ulcer Assessment and Management
- Trigeminal Neuralgia and Treatments
- Facial Nerve Paralysis Treatment and Research
- Streptococcal Infections and Treatments
- Clostridium difficile and Clostridium perfringens research
- Medicinal plant effects and applications
- Hair Growth and Disorders
- Neurofibromatosis and Schwannoma Cases
- Otitis Media and Relapsing Polychondritis
- Thermoregulation and physiological responses
- CNS Lymphoma Diagnosis and Treatment
- Hypertrophic osteoarthropathy and related conditions
- Vascular Malformations and Hemangiomas
Centre Hospitalier Universitaire d'Angers
2017-2025
Université d'Angers
2019-2024
Centre Hospitalier du Mans
2018-2019
Centre Hospitalier Régional Universitaire de Brest
2019
Although cemiplimab has been approved for locally advanced (la) and metastatic (m) cutaneous squamous-cell carcinomas (CSCCs), its real-life value not yet demonstrated. An early-access program enrolled patients with la/mCSCCs to receive cemiplimab. Endpoints were best overall response rate (BOR), progression-free survival (PFS), (OS), duration of (DOR) safety. The 245 (mean age 77 years, 73% male, 49% prior systemic treatment, 24% immunocompromised, 27% Eastern Cooperative Oncology Group...
Abstract Background Interest in the use of omalizumab to treat bullous pemphigoid (BP) event resistance or contraindication conventional therapies is currently based on limited evidence. Objectives To assess effectiveness and safety BP identify predictive factors response treatment. Methods We conducted a French national multicentre retrospective study including patients with confirmed diagnosis treated after failure one several treatment lines. excluded clinically atypical BP, as per...
Objective: We propose a new bidimensional entropy measure and its multiscale form evaluate their behavior using various synthetic real images. The finds application in helping clinicians for pseudoxanthoma elasticum (PXE) detection dermoscopic Method: developed fuzzy (FuzEn <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2D</sub> ) extension (MSF then evaluated them on set of images texture datasets. Afterwards, we applied MSF to PXE compared...
Changes in the duration of efficacy botulinum toxin A injections for primary axillary hyperhidrosis have not been studied depth. The aim this study was to assess such changes. In a retrospective cohort 220 patients, seen over 17-year period, recorded, including first and last injections. Of 117 fulfilled criteria (79 females 38 males, age 17?79 years, mean 38.3 years). Patients received 3?24 (mean 5.5). 3 weeks 30 months (median 6 months), final 66 8 months) (p?
In this study, we propose a new irregularity measure for colored images, the so-called bidimensional fuzzy entropy, FuzEnC <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2D</sub> . This is based on information theory and concept. We test its sensitivity to parameters such as tolerance level window size, well ability quantify different degrees of in image textures. Afterwards, evaluate dermoscopic images two microcirculatory states obtained at...
Brief description of a syringotropic mycosis fungoides. We present the case 83-year-old patient with symmetrical, 3 months old, lesions hands (see Figure 1a). Erythematous scaly on back hand. (a) Clinical photography, (b and c) Microscopic view, x10 x40 zoom respectively, hematoxylin-eosin stain. The histology revealed fungoides 1b,c). This type belongs to subgroup follicular in WHO-EORTC classification cutaneous lymphomas. It can wide variety clinical symptoms.1 Purely pilotropic forms...
BACKGROUND: Pseudoxanthoma elasticum (PXE) is a hereditary disease that manifests - among others with papular lesions on the skin. The presence of these papules earliest sign pathology. Their detection therefore importance but, due to their small size, this can become difficult task. This why dermoscopy, noninvasive imaging modality, may be interest. Nevertheless, dermoscopic images still challenge. OBJECTIVE: We propose an image processing framework help in from images. Our algorithm based...