A5024602019- Autoimmune Bullous Skin Diseases
- Urticaria and Related Conditions
- Inflammatory Myopathies and Dermatomyositis
- Cutaneous lymphoproliferative disorders research
- Eosinophilic Disorders and Syndromes
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Systemic Lupus Erythematosus Research
- Skin Diseases and Diabetes
- Peripheral Neuropathies and Disorders
- Drug-Induced Adverse Reactions
- Nonmelanoma Skin Cancer Studies
- Sarcoidosis and Beryllium Toxicity Research
- Autoimmune and Inflammatory Disorders
- Systemic Sclerosis and Related Diseases
- Mosquito-borne diseases and control
- Cervical Cancer and HPV Research
- Cutaneous Melanoma Detection and Management
- Viral Infections and Vectors
- Contact Dermatitis and Allergies
- T-cell and Retrovirus Studies
- Chronic Lymphocytic Leukemia Research
- Autoimmune and Inflammatory Disorders Research
- Dermatological and COVID-19 studies
- Drug-Induced Ocular Toxicity
- Platelet Disorders and Treatments
Inserm
2001-2025
Université de Rouen Normandie
2000-2025
Normandie Université
2019-2025
Université des Antilles
2015-2024
Centre Hospitalier Universitaire Pointe-à-Pitre
2015-2024
Institut Pasteur de la Guadeloupe
2017-2023
Hospital de Sant Pau
2023
Hospital Regional Universitario de Málaga
2023
Istituto Giannina Gaslini
2023
Istituti di Ricovero e Cura a Carattere Scientifico
2023
Importance Rituximab is approved for the treatment of moderate to severe pemphigus. However, 20% patients in RITUX 3 trial relapsed within first year treatment. Objective To assess outcome an additional rituximab infusion at month 6 with pemphigus who were complete remission (CR) after regimen but had 1 or more predictors relapse 3. Design, Settings, and Participants This multicenter cohort study was conducted France from September 2018 June 2023 newly diagnosed CR Relapse factors a...
Fixed drug eruption (FDE) is one of the most typical cutaneous adverse reactions. This localized drug-induced reaction characterized by its relapse at same sites. Few large series FDE are reported. The aim this study was to retrospectively collect and analyse well informed cases observed in a hospital setting. involved 17 academic clinical centers. A French nation-wide retrospective multicentric carried out on 3-year-period from 2005 2007 collecting data seventeen departments dermatology...
<h3>Objective</h3>To study the relation between blood concentration of hydroxychloroquine and clinical efficacy sulfate in a series patients with cutaneous lupus erythematosus (CLE).<h3>Design</h3>Prospective multicenter study. A staff dermatologist blinded to concentrations performed standardized review medical records assessment following 3 categories: complete remission, partial remission (clearing >50% skin lesions), or treatment failure. Whole-blood samples were collected for...
Objective. Cardiac involvement during systemic lupus erythematosus (SLE) may include the pericardium, myocardium, valvular tissue, and coronary arteries. The aim of this study was to describe clinical, biological, radiological presentation myocarditis (LM) as well treatment response longterm outcomes. Methods. We conducted a multicentric retrospective LM from January 2000 May 2014. Results. Twenty-nine patients (3 men 26 women) fulfilled inclusion criteria (median age at diagnosis SLE: 30...
<i>Background:</i> Unexpected cases of bullous pemphigoid (BP) have been reported in adult patients with various neurological disorders suggesting a possible relationship between these diseases. <i>Objectives:</i> (1) To determine the prevalence and types BP, (2) to assess patients’ functional impairment, (3) compare clinical biological findings as well prognosis BP presenting or without disorders. <i>Methods:</i> were selected series 341 consecutive...
<h3>Objective</h3> To identify prognostic factors for relapse in the first year after cessation of therapy bullous pemphigoid (BP). <h3>Design</h3> Prospective, multicenter, cohort study (January 1, 2000, through December 31, 2006). <h3>Setting</h3> Fifteen French dermatology departments. <h3>Patients</h3> Patients with BP remission under low doses topical or systemic corticosteroids. <h3>Interventions</h3> Cessation corticosteroid treatment (day 0) followed by a systematic clinical and...
Lymphomatoid papulosis (LyP) is classified as an indolent cutaneous lymphoma, but outcome dramatically worsens if LyP associated with lymphoma. The frequency of this association remains unclear in the literature. Here, we assess and risk factors between another lymphoma 11-year retrospective study conducted 8 dermatology departments belonging to French Study Group on Cutaneous Lymphoma (FSGCL).Patients were identified data extracted from FSGCL registry 1991 2006. Patients followed up January...
Objective Anti–transcription intermediary factor 1γ (anti‐ TIF 1γ) antibodies are the main predictors of cancer in dermatomyositis ( DM ). Yet, a substantial proportion anti‐ 1γ–positive patients do not develop cancer. This study was undertaken to identify biomarkers better evaluate risk and mortality . Methods multicenter conducted adult from August 2013 2017. Anti‐ autoantibody levels IgG subclasses were identified using newly developed quantitative immunoassay. Age, sex, signs activity,...
This cohort study examines the safety and efficacy of rituximab for patients with pempigus foliaceus.
Abstract Background Identification of myositis‐specific autoantibodies ( MSA s) for dermatomyositis DM ) could allow the characterization an antibody‐associated clinical phenotype. Objective We sought to define phenotype and risk cancer, interstitial lung disease ILD calcinosis based on . Methods A 3.5‐year multicentre prospective study adult patients was conducted determine associated with s presence calcinosis. Results were detected in 47.1% 117 included patients. Patients antimelanoma...
Abstract Background There are no reliable epidemiological data on sarcoidosis in the F rench W est I ndies, although this disease is known to be more frequent and severe B lack A frican‐ mericans ndians. Objectives This retrospective study aimed assess incidence prevalence of Guadeloupe over a 7‐year period determine its epidemiological, clinical, evolutionary characteristics. Methods Patients were identified through computerized databases three pathology laboratories two hospitals islands...
Adverse pregnancy outcomes (APO) occur in 35% of patients with pemphigoid gestationis (PG). No biological predictor APO has been established yet.To assess a potential relationship between the occurrence and serum value anti-BP180 antibodies at time PG diagnosis.Multicentre retrospective study conducted from January 2009 to December 2019 35 secondary tertiary care centres.(i) diagnosis according clinical, histological immunological criteria, (ii) ELISA measurement IgG determined same...
Mastocytosis is a group of disorders characterized by abnormal mast cell proliferation, involving the skin in 80% cases. Cutaneous mastocytosis, which appears childhood 60% cases, usually has benign course with gradually regressive evolution before puberty. Mast sarcomas, part systemic forms are very rare tumors destructive growth highly atypical cells, secondary spread, poor prognosis, and low survival rates. We report first known case primary cutaneous sarcoma due to transformation...
The nosology of bullous lesions or equivalents (vesicles, erosions, and crusts) in patients with lupus erythematosus (LE) is rarely addressed. primary aim this study was to draw up a precise phenotypic inventory such skin lesions; the secondary objective assess potential relationship between different types loss epidermis extracutaneous manifestations. We conducted retrospective multicenter including 22 definite LE equivalents. All biopsies were reviewed. Patients recruited dermatology...
Abstract There is a need for training dermatologists in skin of colour's common and less dermatoses due to the increasing diversity world population. The aim this review highlight on cutaneous manifestations systemic diseases Afro‐Caribbean people, especially sarcoidosis, dermatomyositis, sclerosis, lupus.