Yuchuan Zhao

ORCID: 0000-0003-3834-6368
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About
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Research Areas
  • Tuberculosis Research and Epidemiology
  • Mycobacterium research and diagnosis
  • Concrete Corrosion and Durability
  • Sensor Technology and Measurement Systems
  • Infectious Diseases and Tuberculosis
  • Biochemical and Molecular Research
  • Human Mobility and Location-Based Analysis
  • Obstructive Sleep Apnea Research
  • Extracellular vesicles in disease
  • Cancer-related molecular mechanisms research
  • RNA Interference and Gene Delivery
  • Masonry and Concrete Structural Analysis
  • Moringa oleifera research and applications
  • Natural product bioactivities and synthesis
  • Gut microbiota and health
  • MicroRNA in disease regulation
  • Metabolomics and Mass Spectrometry Studies
  • Concrete and Cement Materials Research
  • Privacy-Preserving Technologies in Data
  • Antibiotic Resistance in Bacteria
  • Recommender Systems and Techniques
  • Essential Oils and Antimicrobial Activity
  • Diagnosis and treatment of tuberculosis
  • Structural Behavior of Reinforced Concrete
  • Advanced Sensor and Control Systems

Center for Tuberculosis Control of Guangdong Province
2022-2024

Shanghai Tongji Urban Planning and Design Institute
2023

Anhui University
2022

University of Shanghai for Science and Technology
2022

Guangxi University
2018

Harbin Engineering University
2015

Cross-Domain Recommendation (CDR) aims to solve data sparsity and cold-start problems by utilizing a relatively information-rich source domain improve the recommendation performance of data-sparse target domain. However, most existing approaches rely on assumption centralized storage user data, which undoubtedly poses significant risk privacy leakage because are highly privacy-sensitive. To this end, we propose privacy-preserving Federated framework for Recommendation, called FedCDR. In our...

10.1016/j.dcan.2022.04.034 article EN cc-by-nc-nd Digital Communications and Networks 2022-05-05

In reinforced concrete (RC) structures, new-to-old interfaces are widely present due to precast splices, repairs, and construction joints. this paper, both monolithic segmental specimens were fabricated with five kinds of water-cement ratios, including ordinary high-strength concrete. The impressed current-accelerated corrosion test was used, the degree reinforcement controlled by Faraday's Law. accelerated process, surface cracking, steel corrosion, mechanical properties corroded steels in...

10.3390/ma16175969 article EN Materials 2023-08-31

Obstructive sleep apnea (OSA) is highly prevalent, but frequently undiagnosed. The existing biomarkers of OSA are relatively insensitive and inaccurate. Long non-coding RNAs (lncRNAs) have no protein-coding ability a role in regulating gene expression. They stably expressed exosomes, easily rapidly measurable. Changes expression exosomal lncRNAs can be useful for disease diagnoses. However, there few reports on the association with OSA. We aimed to investigate lncRNA profiles establish...

10.21037/atm-22-3818 article EN Annals of Translational Medicine 2022-09-01

Antibiotic resistance of Mycobacterium tuberculosis (Mtb) is a major public health concern worldwide. Therefore, it great significance to characterize the mutational pathways by which susceptible Mtb evolves into drug resistance. In this study, we used laboratory evolution explore aminoglycoside The level in amikacin inducing was also associated with changes susceptibility other anti-tuberculosis drugs such as isoniazid, levofloxacin and capreomycin. Whole-genome sequencing (WGS) revealed...

10.1099/mgen.0.001022 article EN cc-by Microbial Genomics 2023-05-24

Ethambutol (EMB) is a first-line antituberculosis drug currently being used clinically to treat tuberculosis. Mutations in the embCAB operon are responsible for EMB resistance. However, discrepancies between genotypic and phenotypic resistance have attracted much attention. We induced Mycobacterium tuberculosis vitro an integrated genome-methylome-transcriptome-proteome approach study microevolutionary mechanism of identified 509 aberrantly methylated genes (313 hypermethylated 196...

10.3389/fcimb.2022.959911 article EN cc-by Frontiers in Cellular and Infection Microbiology 2022-08-31

Currently, there are no particularly effective biomarkers to distinguish between latent tuberculosis infection (LTBI) and active pulmonary (PTB) evaluate the outcome of TB treatment. In this study, we have characterized changes in serum metabolic profiles caused by Mycobacterium (Mtb) standard anti-TB treatment with isoniazid–rifampin–pyrazinamide–ethambutol (HRZE) using GC-MS LC-MS/MS. Seven metabolites, including 3-oxopalmitic acid, akeboside ste, sulfolithocholic 2-decylfuran...

10.3389/fpubh.2022.962510 article EN cc-by Frontiers in Public Health 2022-11-15

Background microRNAs (miRNAs) were recognized as a promising source of diagnostic biomarker. Herein, we aim to evaluate the performance an ultrasensitive method for detecting serum miRNAs using single molecule arrays (Simoa). Methods In this study, candidate trained and tested by RT-qPCR in cohort PTB patients. Besides that, miRNA detection developed Single Molecule Array (Simoa) platform. ultra-sensitive sandwich assay, two target-specific LNA-modified oligonucleotide probes can be simply...

10.3389/fimmu.2024.1418085 article EN cc-by Frontiers in Immunology 2024-09-02

Abstract The problem of bacterial resistance is becoming more and serious, which has become an urgent to be solved in human veterinary. One approach control delay combination therapy antibiotics are given together with other antimicrobial or non-antimicrobial agents. Studies have shown that flavonoids from Traditional Chinese medicine (TCM) possess a high level antibacterial activity against antibiotic resistant strains. aim this study was evaluate the effects combined total Ilex rotunda...

10.1101/457911 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2018-10-31

This paper introduces a kind of receiver that can receive signal which weak to UV level.First, the common mode rejection for input differential is necessary, and low noise amplifier followed by.Then we should let go through Programmable filter whose center frequency, Q are all selected via pin-strapped inputs.In order get appropriate amplitude signal, an automatic gain control needed.Last, before sampled by A/D converters, active operational AGC amplifier.Through actual test, frequency with...

10.2991/icismme-15.2015.273 article EN cc-by-nc Advances in intelligent systems research/Advances in Intelligent Systems Research 2015-01-01

<p>To facilitate the reuse of internal mold precast multi-box girder and accelerate bridge construction, torsional crossbeam at end simply supported needs to be changed post-cast in-situ. Finite Element Modelling package ABAQUS 2021 was used model interfacial shear behaviour three-dimensional Z-shaped straight specimens. The models took into account bond-slip relationship between old new concrete interfaces interaction key. were validated calibrated based on experimental results. study...

10.2749/nanjing.2022.0767 article EN Report 2022-01-01
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