Colistin is considered to be an antimicrobial of last-resort for the treatment multidrug-resistant Gram-negative bacterial infections. The recent global dissemination mobilized colistin resistance (mcr) genes urgent public health threat. An accurate estimate prevalence mcr genes, their reservoirs and potential pathways human transmission are required implement control prevention strategies, yet such data lacking. Publications from four English (PubMed, Scopus, Cochrane Database Systematic...

Antimicrobial-resistant Salmonella enterica poses a significant public health concern worldwide. However, the dissemination of among food animals in eastern China has not been fully addressed. Here, we demonstrated antimicrobial resistance (AMR) patterns and whole-genome characterization 105 S. isolates from 1,480 fecal samples anal swabs collected 22 different farms (chickens, ducks, pigs) two live animal markets located Zhejiang Fujian Provinces 2019. The prevalence duck (19.17%, 23/120)...

The fatal impairment of the intestinal mucosal barrier chicks caused by Salmonella significantly resulting economic losses in modern poultry industry. Probiotics are recognized for beneficially influencing host immune responses, promoting maintenance epithelial integrity, antagonistic activity against pathogenic microorganisms and health-promoting properties. Some basic studies attest to probiotic capabilities show that Lacticaseibacillus rhamnosus could protect mucosa from injury animals...

Worldwide emergence of Salmonella enterica serovar Newport (S. Newport) infection in humans, parallel with a significant increasing prevalence antimicrobial resistance (AR), is serious public health concern. However, the S. China remains largely unknown. A retrospective study 287 clinical isolates collected during 1997–2018 was undertaken for characterization AR profiles using micro-dilution assay. We found recent colistin four Chinese isolates, including mcr-1-positive isolates....

The similarity of the Listeria innocua genome with monocytogenes and their presence in same niche may facilitate gene transfer between them. A better understanding mechanisms responsible for bacterial virulence requires an in-depth knowledge genetic characteristics these bacteria. In this context, draft whole sequences were completed on five L. isolated from milk dairy products Egypt. assembled screened antimicrobial resistance genes, plasmid replicons multilocus sequence types (MLST);...

Abstract Background Salmonella enterica subsp. serovar Dublin ( S . Dublin), a cattle adapted causes enteritis, and systemic disease in bovines. The invasive index of this far exceeds that the other serovars human infections often present as fatal or highly resistant infections. In this, observational study, phenotypic properties bovine-derived isolates along with antibiogram common antimicrobials were evaluated. multiplex PCR confirmed genotyped using 7-gene legacy MLST. MIC assay was done...

Salmonella enterica serovar 4,[5],12:i:-, so-called Typhimurium monophasic variant, has become one of the most frequently isolated serovars both in humans and animals all over world. The increasing prevalence mcr-1-carrying poses significant global health concerns. However, potential role 4,[5],12:i:- mcr-1 gene migration through food chain to human remains obscure. Here, we investigated 337 isolates from apparently healthy finishing pigs, which is rarely studied, obtained pig farms...

Salmonella spp. are recognized as important foodborne pathogens globally. enterica serovar Rissen is one of the serovars linked with swine products in numerous countries and can transmit to humans by food chain contamination. Worldwide emerging S. considered most common cause human salmonellosis. The objective this study was determine antimicrobial resistance properties patterns isolates obtained from humans, animals, animal-derived products, environment China. Between 2016 2019, a total 311...

Background: Foodborne outbreaks caused by Campylobacter jejuni have become a significant public health problem worldwide. Applying genomic sequencing as routine part of foodborne outbreak investigation remains in its infancy China. We applied both traditional PFGE profiling and to understand the cause Hangzhou December 2018. Method: A total 43 fecal samples, including 27 sick patients 16 canteen employees from high school city Zhejiang province, were recruited. Routine real-time fluorescent...

Salmonella spp. is recognized as an important zoonotic pathogen. The emergence of antimicrobial resistance in enterica poses a great public health concern worldwide. While the knowledge on incidence and characterization different S. serovars causing chick embryo death remains obscure China. In this study, we obtained 45 isolates from 2,139 dead samples collected 28 breeding chicken hatcheries Henan province. susceptibility assay was performed by broth microdilution method results showed that...

Antimicrobial resistance is a major concern in the dairy industry. This study investigated prevalence, antimicrobial phenotypes, and genome sequencing of Gram-negative bacteria isolated from clinical (n = 350) subclinical 95) bovine mastitis, raw unpasteurized milk 125). Klebsiella pneumoniae, Aeromonas hydrophila, Enterobacter cloacae (100% each), Escherichia coli (87.78%), Proteus mirabilis (69.7%) were most prevalent multidrug-resistant (MDR) species. Extensive drug-resistance (XDR)...

The United Arab Emirates (UAE) has witnessed rapid urbanization and a surge in pet ownership, sparking concerns about the possible transfer of antimicrobial resistance (AMR) from pets to humans environment. This study delves into whole-genome sequencing analysis ESBL-producing E. coli strains healthy cats dogs UAE, which exhibit multidrug (MDR). Additionally, it provides genomic exploration mobile colistin gene mcr-1.1, marking first instance its detection Middle Eastern pets.We investigate...

To investigate the genetic basis of carbapenem resistance in clinical S. marcescens isolates collected from patients Japan between 1994 and 2016. 5135 were recovered different medical centers across Japan, identified central laboratories, tested for antimicrobial agents using broth microdilution method. All that showed intermediate or resistant phenotypes at least one antibiotic confirmed by susceptibility testing carbapenemase production modified inactivation method (mCIM). Furthermore,...

The prevalence of antimicrobial resistance in zoonotic Salmonella is a significant ongoing concern over the world. Several reports have investigated infections farm animals China; however, there only limited knowledge about cross-contamination slaughterhouses. Moreover, application genomic approaches for understanding food-animal slaughterhouses still its infancy China. In present study, we isolated 105 strains from pig carcasses and environment samples collected four independent Jiangsu,...

In this study, multidrug-resistant (MDR) Escherichia coli isolates from retail food and humans assigned into similar Multilocus Sequence Types (MLST) were analyzed using whole genome sequencing (WGS). silico analysis of assembled sequences revealed the existence multiple resistance genes among examined E. isolates. Of six CTX-M-producing food, bla CTX-M-14 was prevalent variant identified (83.3%, 5/6). Two plasmid-mediated fosfomycin genes, fosA3, fosA4, detected (one each chicken beef),...

This study aimed to investigate the occurrence and characteristics of Salmonella isolates in salad vegetables United Arab Emirates (UAE). Out 400 samples tested from retail, only 1.25% (95% confidence interval, 0.41-2.89) were found be positive for Salmonella, all which conventional local produce, presented at ambient temperature, featured as loose items. The five Salmonella-positive arugula (n = 3), dill 1), spinach 1). pan-susceptible a panel 12 antimicrobials using disc diffusion assay....

Colistin is considered to be a ‘last-resort’ antimicrobial for the treatment of multidrug-resistant Gram-negative bacterial infections. Identification Enterobacteriaceae, carrying transferable colistin resistance gene mcr-1, has recently provoked global health concern. This report presents first detection hydrogen sulfide (H2S)-producing Escherichia coli variant isolated from human in China, with multidrug (MDR) properties, including by mcr-1 gene, which could have great implications

Salmonellosis represents a growing threat to global public health. Salmonella enterica remains the leading cause of bacterial foodborne diseases in China. serovar Rissen ( S . Rissen) has been recognized as one emerging serovars among humans different countries worldwide. However, knowledge on prevalence China is largely lacking. To address essential epidemiological information for China, total 1,182 isolates recovered from samples across food chain were collected 16 provinces or...