A5061297025- Antibiotic Resistance in Bacteria
- Antibiotic Use and Resistance
- Antibiotics Pharmacokinetics and Efficacy
- Vibrio bacteria research studies
- Infections and bacterial resistance
- Biosensors and Analytical Detection
- Dermatology and Skin Diseases
- Reproductive tract infections research
- Cystic Fibrosis Research Advances
- Plant Pathogenic Bacteria Studies
- Escherichia coli research studies
- Galectins and Cancer Biology
- Probiotics and Fermented Foods
- Systemic Lupus Erythematosus Research
- Circular RNAs in diseases
Cairo University
2019-2024
Background Vulvovaginal candidiasis (VVC) is a highly prevalent illness affecting women globally. Lactobacilli, which make up the majority of healthy vaginal microbiota (VMB), serve as powerful barrier against infections. Probiotic therapy has been recommended for treatment or prevention VVC. Aim work To compare in vivo therapeutic effects Lactobacillus johnsonii (B-2178) vs. acidophilus (LA-5 ® ) on VVC rat model, particularly highlighting immune response host epithelium. Methods In total,...
Background. The global incidence of carbapenem-resistant Enterobacterales (CRE) is increasing, posing a major treatment challenge and serious infection control concern. Objective. We aimed to characterize carbapenemases both genotypically phenotypically among CRE isolated from two tertiary hospitals in Egypt, detect the genetic relatedness studied isolates. Methodology. A total 107 non-duplicate strains different clinical specimens hospitalized patients were assessed for presence genes using...
Background: Cystic fibrosis (CF) is a genetically recessive disease marked by frequent, chronic lung infections that impair function and cause early death. Objectives: our aim was to identify the bacteria colonizing airways among cohort of Egyptian children with CF assess their antimicrobial susceptibility biofilm formation capacity. Methodology: In this cross-sectional study, we assessed prevalence bacterial species 34 pediatric patients CF. The isolated pathogens underwent antibiotic...
Background. Ceftazidime-avibactam (CZA) and meropenem-vaborbactam (MVB) are novel therapeutic options for infections caused by carbapenem-resistant Enterobacterales (CRE). Our study aimed to evaluate the in vitro activity of CZA MVB, against a diverse collection CRE assess accuracy disc diffusion method compared E-test. Methods. 70 isolated from hospitalized patients Egypt were included our study. The susceptibility profiles these isolates MVB determined using E-test methodologies. studied...
The emergence of carbapenem-resistant
Background: Carbapenem resistant Enterobacteriaceae (CRE) have been reported worldwide. Resistance to carbapenems in is caused mainly by carbapenemase production or porin loss combined with the expression of beta (β)lactamases like extended-spectrum β-lactamases (ESBL) ampicillin class C (AmpC). Objectives are determine prevalence carbapenemase-producing (CPE) among 202 clinical isolates phenotypic test modified carbapenem inactivation method (mCIM). Methodology: Initial screening for was...
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with heterogeneous manifestations and intricate pathophysiology. Driven by its complicated diagnostic framework, an interest in innovative approaches has been steadily growing. Circular RNAs (circRNAs) are novel class of noncoding involved the development various diseases including SLE. To investigate circPTPN22, microRNA-200a-3p (miR-200a-3p) interleukin-2 (IL-2) SLE patients study their potential. The included 45 control....