A5100785526- Cardiac, Anesthesia and Surgical Outcomes
- Liver Disease Diagnosis and Treatment
- Alcohol Consumption and Health Effects
- Hepatocellular Carcinoma Treatment and Prognosis
- Allergic Rhinitis and Sensitization
- Ear and Head Tumors
- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Contact Dermatitis and Allergies
- Epigenetics and DNA Methylation
- Chromatin Remodeling and Cancer
- Plant Reproductive Biology
- Food Allergy and Anaphylaxis Research
- Hedgehog Signaling Pathway Studies
- Viral Infections and Vectors
- Garlic and Onion Studies
- RNA modifications and cancer
- Tumors and Oncological Cases
- Cancer Diagnosis and Treatment
- Workplace Health and Well-being
- SARS-CoV-2 and COVID-19 Research
- PARP inhibition in cancer therapy
- Sleep and Work-Related Fatigue
- Transcranial Magnetic Stimulation Studies
- Aortic aneurysm repair treatments
Ulsan College
2014-2024
University of Ulsan
2014-2024
Asan Medical Center
2014-2024
Incheon Medical Center
2021-2022
Kyung Hee University
2021
Daegu-Gyeongbuk Medical Innovation Foundation
2019
Seoul National University Hospital
2019
Korea National Institute of Health
2009-2017
Yeouido St. Mary's Hospital
2015
Catholic University of Korea
2013-2015
We present autopsy findings of a 22-year-old man who developed chest pain 5 days after the first dose BNT162b2 mRNA vaccine and died 7 hours later. Histological examination heart revealed isolated atrial myocarditis, with neutrophil histiocyte predominance. Immunohistochemical C4d staining scattered single-cell necrosis myocytes which was not accompanied by inflammatory infiltrates. Extensive contraction band observed in atria ventricles. There no evidence microthrombosis or infection other...
Background: The Korea Nurses' Health Study (KNHS) is a prospective cohort study of female nurses, focusing on the effects occupational, environmental, and lifestyle risk factors health Korean women. Materials Methods: Female registered nurses aged 20–45 years living in Republic were invited to join study, which began July 2013. They asked complete web-based baseline survey. protocols questionnaires related KNHS are based 3 (NHS3) United States, although they modified reflect lifestyle....
Ga Hee Kim, Ji Yong Ahn, Hwoon-Yong Jung, Young Soo Park, Min-Ju Kee Don Choi, Jeong Hoon Lee, Kwi-Sook Do Hyun Lim, Ho June Song, Gin Hyug and Jin-Ho Kim. Gut Liver 2015;9:615-22. https://doi.org/10.5009/gnl14032
To examine the function of SIRT1 in neuronal differentiation, we employed all‐trans retinoic acid (ATRA)‐induced differentiation neuroblastoma cells. Nicotinamide inhibited neurite outgrowth and tyrosine hydroxylase (TH) expression. Inhibition PARP or histone deacetylase did not inhibit TH expression, showing effect to be specific. Expression FOXO3a its target proteins were increased during reduced by nicotinamide. deacetylation was ATRA blocked siRNA ATRA‐induced up‐regulation...
Purpose: Sonic hedgehog (Shh) signaling pathway is known to play a crucial role in carcinogenesis various malignancies, including lung cancer regarding tumorigenesis, angiogenesis, and cellular differentiation.The aim of this study was investigate the value components Shh as prognostic marker extensive stage small cell (ES-SCLC) patients. Materials Methods:We retrospectively analyzed data 36 patients who were diagnosed with ES-SCLC between 2008 2012 at single center.We performed...
This study aimed to analyze the epidemiology of congenital upper limb anomalies (CULA) in Korea. We evaluated incidence each type CULA, presence coexisting and surgical treatment status CULA patients. conducted a retrospective cohort patients aged < 1 year between 2007 2016 who were registered with Health Insurance Review Assessment Service In total, 10,704 had including 6,174 boys (57.7%) 4,530 girls (42.3%). The mean annual was 23.5 per 10,000 live births; it significantly higher than...
Aim of the present study was to define relationship between petrous apex pneumatization and nearby major anatomical landmarks using temporal bone computed tomography (CT) images.This retrospective, Institutional Review Board-approved analyzed CT images 84 patients that showed normal findings bilaterally. Pneumatization classified two methods. Eight parameters were as follows: angle posterior cranial fossa internal auditory canal, Morimitsu classification anterior epitympanic space, distance...
Results: The sensitization rates to Tree pollen mixture I and II were increased as 5.0%, 6.8% in 2000, 8.5%, 9.8% 2005, 14.8%, 17.3% 2010, respectively (trend P < 0.001, respectively). And the D. pteronyssinus cat dander dog changed 55%, 4.8%, 4.8% 62.2%, 11.9%, 28% 63.1%, 12.7%, 16.7% respectively. distribution of sensitized pollens was oak (12.8%), beech (12.4%), pine (10.3%), birch (10%), hazel (9.6%), alder (8%), elder (6.9%), elm (5.4%) study 2010. When allergen/histamine ratio...
Previous studies report that organo-sulfur compounds derived from garlic inhibited smooth muscle cell (SMC) proliferation and induced apoptosis of cancer cells. Recently, lipid-soluble such as diallyl sulfides (DAS) disulfides (DADS) have been reported to more effectively suppress tumor proliferation. However, there were few on the suppressive effects sulfur migration vascular cells (VSMC). Therefore, this study investigated effect DAS DADS VSMC proliferation/migration by oleic acid (OA), a...
Neuraminidase is an important target for influenza vaccination. In this study, we generated avian VLPs, expressing hemagglutinin (HA), neuraminidase (NA), HA and NA co-expressed (HANA), to evaluate the protective role of against a high (10LD50) low (2LD50) dose virus challenge infections. A single immunization with HANA VLPs elicited highest level virus-specific IgG, IgG1, IgG2a responses from sera post-vaccination lungs post-challenge-infection. Potent antibody-secreting cell were observed...
Abstract BACKGROUND Motor dysfunctions in Parkinson disease (PD) patients are not completely normalized by deep brain stimulation (DBS), and there is an obvious difference the degree of symptom improvement after DBS for each patient. OBJECTIVE To test our hypothesis that patient has their own restoration capacity motor DBS, to investigate whether regional cerebral glucose metabolism 18 F-fluorodeoxyglucose positron emission tomography (FDG-PET) scans associated with off-medication (MI off )...
Hemangioma is one of the most common benign neoplasm involved on head and neck. However, cavernous hemangiomas are relatively rare in preauricular sinus space has rarely been reported around world. Recently, a 44-year-old female patient came to our clinic with hemangioma involving sinus. This case was surgically managed via excision. Preoperatively, it difficult differentiate mass clinically diagnostically from fistula, salivary gland tumor, or an enchondroma. report describes subcutaneous...
배수체는 무핵 감귤 육종 프로그램 있어서 잠재적으로 매우 중요한 유전자원이다. 무핵성은 만다린 품종이 갖추어야 할 가장 유망한 형질 중 하나이고 3배체는 영구적으로 무핵이다. 새로운 3배체 잡종은 이종속간 배수체의 교배 또는 저빈도의 2배성 배우체 형성과 합성 같은 행동에 기인된 2배체 이종간 교배로도 이룰 수 있다. 그러나 소립의 <TEX>$F_1$</TEX> 종자로 발달된 이 형태에 기초한 육종은 효과적인 무균적 배 적출 및 배양법 없이는 불가능하다. 본 연구에서, 무균의 배배양을 이용하여 단배의 제주 재래귤과 만다린잡종에서 방임 수분되어 자연적으로 발생한 소립종자로부터 유묘를 얻었고 배수 검정기를 정도를 검정하여 다양한 수준의 배수체를 획득하였다. 총 792 과실을 10,289 개의 획득된 종자를 분석하여 과실당 평균 13개의 종자가 함유됨을 알 있었다. 정상종자와 유사한 형태로 소립종자의 과실 내 함유율은 7.1%였다. 출현 빈도는 '클레멘타인', '하레히메',...
Abstract PC12 cells were differentiated into the of chromaffin phenotype by butyrate treatment. Cells aggregated and formed tight cell adhesion. To investigate molecular change in this differentiation, we examined expression levels adhesion proteins extracellular during induced-differentiation cells. Integrin β1, integrin α7, E cadherin, VCAM, collagen-I, fibronectin, desmoglein connexin increased differentiation. The clusterin secreted also increased. These appear to induce aggregation p21,...
To propose a new, multivariable risk-scoring model for predicting 30-day mortality in individuals underwent repair of abdominal aortic aneurysms (AAA).Four hundred eighty-five consecutive patients who AAA from January 2000 to December 2010 were included the study. Univariate and multivariate analyses performed evaluate risk factors, was developed.Multivariate analysis identified three independent preoperative factors associated with mortality, created by assigning an equal value each factor....
<title>Abstract</title> Activating transcription factor 3 (ATF3) is a critical regulator for cellular stress responses and implicated in stress-induced cardiac hypertrophy fibrosis. However, the role of ATF3 cardiomyopathy remains controversial. Here, we demonstrate that plays cardioprotective by controlling mitochondrial oxidative angiotensin II (Ang II)-triggered cardiomyopathy. The expression was significantly upregulated hypertrophic hearts chronically infused with Ang II, which...
The impact of complete revascularization (CR), achieved through the recanalization coronary chronic total occlusions (CTOs), on long-term patient outcomes remains uncertain. To evaluate this in patients who CR after CTO-PCI with those did not due to deferred CTO-PCI, Asan Medical Center Registry was reviewed identify artery disease (CAD) CTOs treated between January 2003 and December 2018. Patients were included single-vessel CTO multivessel had undergone for non-CTO lesions. These subjects...
Purpose: Food-dependent exercise-induced anaphylaxis (FDEIA) is a specific clinical syndrome requiring both ingestion of an allergenic food and exercise to induce anaphylaxis. It may be underdiagnosed due insufficient history taking in terms the causes This study aims describe characteristics diagnostic results FDEIA children. Methods: We retrospectively reviewed medical records patients under 18 years old who were diagnosed with at Asan Medical Center between January 2003 August 2014....