- Natural product bioactivities and synthesis
- Genomics, phytochemicals, and oxidative stress
- Wound Healing and Treatments
- Pharmacological Effects of Natural Compounds
- Phytochemistry and Bioactive Compounds
- Essential Oils and Antimicrobial Activity
- Bee Products Chemical Analysis
- Helicobacter pylori-related gastroenterology studies
- Disaster Response and Management
- Agricultural pest management studies
- Biochemical and biochemical processes
- Sesquiterpenes and Asteraceae Studies
- Herbal Medicine Research Studies
- Selenium in Biological Systems
- Plant Toxicity and Pharmacological Properties
- Pomegranate: compositions and health benefits
- NF-κB Signaling Pathways
- Banana Cultivation and Research
- Maternal and Neonatal Healthcare
- Sulfur Compounds in Biology
- Insect Pest Control Strategies
- Diabetic Foot Ulcer Assessment and Management
- Organoselenium and organotellurium chemistry
- Global Energy and Sustainability Research
- Toxin Mechanisms and Immunotoxins
Petrobras (Brazil)
2024
Universidade Estadual Paulista (Unesp)
2016-2022
Morpho (United States)
2017
Universidade Federal de Roraima
2017
Universidade Federal de Santa Catarina
2014
Impaired wound healing is a debilitating complication of diabetes that leads to significant morbidity, particularly foot ulcers. Natural products have shown be effective in treating skin wounds. Lupeol known stimulate angiogenesis, fibroblast proliferation, and expressions cytokines growth factors involved healing. The study performed evaluate the activity lupeol streptozotocin-induced hyperglycemic rats by macroscopical, histological, immunohistochemical, immunoenzymatic, molecular methods....
Skin wound healing is a highly complex event that involves different mediators at the cellular and molecular level. Lupeol has been reported to possess biological activities, such as anti-inflammatory, antioxidant, antidiabetic, in vitro properties, which motivated us proceed with vivo studies. We aimed investigate effect of lupeol-based cream for 3, 7, 14 days. Wound excisions were induced on thoraco-lumbar region rats topically treated immediately after injury induction. Macroscopic,...
Gastric ulcer is one of the most frequent gastrointestinal disorders, and there an increasing search for natural products that can heal ulcers avoid their recurrence. We aimed to evaluate gastroprotective activity vanillin, including investigation anti-inflammatory modulation gene expression. Wistar rats were orally treated with vehicle, carbenoxolone, or vanillin (25, 50, 100 mg/kg) received absolute ethanol develop gastric ulcers. analyzed area, conducted histological analysis, measured...
Wound healing involves inflammatory, proliferative, and remodeling phases, in which various cells chemical intermediates are involved. This study aimed to investigate the skin wound potential of menthol, as well mechanisms involved its effect, after 3, 7, or 14 days treatment, according phases healing. Skin was performed back Wistar rats, were topically treated with vehicle cream; collagenase-based cream (1.2 U/g); menthol-based at 0.25%, 0.5%, 1.0% over days. Menthol 0.5% accelerated right...
The wound healing is a complex process which, sometimes, can be problem in public health because of the possibility physical disability or even death. Due to lack gold standard drug skin treatment and aiming at discovery new treatments repair mechanisms involved process, we used oleoresin (OR) from Copaifera langsdorffii hydroalcoholic extract leaves (EH) treat rat wounds. For that, male Wistar rats were divided into groups ( n = 8): Lanette, Collagenase, 10% EH, OR and, after anesthesia,...
This study aimed to verify the insecticidal activity and determine LC50 of hydroethanolic extracts from Annona montana leaves seeds on black aphid, Aphis craccivora. The experiment was conducted in a greenhouse. leaf seed were obtained by solvent extraction using 70% ethanol. following spray treatments applied aphid nymphs: Hydroethanol (HE) at concentrations 2.5; 5; 10; 15%, EH 0.5; 1.0; 1.5; 2%; Neemax® distilled water (control). Results showed presence effect both A. craccivora nymphs. HE...
Abstract The Subsea High-Pressure Separation, in this paper named as SHPS, is an innovative subsea separation technology designed to separate gas with high-CO2 content from the reservoir-produced fluid at seabed. This operates under high-pressure conditions and utilizes centrifugal pumps directly reinject separated stream back into reservoir. By removing excess of high CO2 content, SHPS enables efficient contributes emissions intensity reduction, making it a promising system for carbon...