A5101440269- Genetic Associations and Epidemiology
- Advanced Neuroimaging Techniques and Applications
- Metabolism and Genetic Disorders
- Diet and metabolism studies
- Mitochondrial Function and Pathology
- Pluripotent Stem Cells Research
- Alzheimer's disease research and treatments
- Advanced MRI Techniques and Applications
- Dementia and Cognitive Impairment Research
- Histone Deacetylase Inhibitors Research
- Medical Imaging Techniques and Applications
- Schizophrenia research and treatment
Lieber Institute for Brain Development
2016-2018
National Institute of Mental Health
2016
National Institutes of Health
2016
Virginia Commonwealth University
2010
High-resolution three-dimensional magnetic resonance imaging (3D-MRI) is being increasingly used to delineate morphological changes underlying neuropsychiatric disorders. Unfortunately, artifacts frequently compromise the utility of 3D-MRI yielding irreproducible results, from both type I and II errors. It therefore critical screen 3D-MRIs for before use. Currently, quality assessment involves slice-wise visual inspection volumes, a procedure that subjective time consuming. Automating rating...
The use of polygenic risk scores has become a practical translational approach to investigating the complex genetic architecture schizophrenia, but link between and pathophysiological components this disorder been subject limited research. We investigated in healthy volunteers whether schizophrenia score predicts hippocampal activity during simple memory encoding, which proposed as risk-associated intermediate phenotype schizophrenia. analysed relationship discovery sample 191 unrelated from...