A5085509317- Breast Cancer Treatment Studies
- HER2/EGFR in Cancer Research
- Cancer Cells and Metastasis
- Gold and Silver Nanoparticles Synthesis and Applications
- AI in cancer detection
- Nanoplatforms for cancer theranostics
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Head and Neck Cancer Studies
- Cancer, Lipids, and Metabolism
- Cancer-related molecular mechanisms research
- Radiomics and Machine Learning in Medical Imaging
- Inflammatory Biomarkers in Disease Prognosis
- Medical Imaging Techniques and Applications
- Metastasis and carcinoma case studies
- Salivary Gland Tumors Diagnosis and Treatment
- MRI in cancer diagnosis
- 3D Printing in Biomedical Research
- Microfluidic and Bio-sensing Technologies
- Cancer Treatment and Pharmacology
- Photoacoustic and Ultrasonic Imaging
- Cancer, Hypoxia, and Metabolism
- Esophageal Cancer Research and Treatment
Renji Hospital
2024-2025
Shanghai Jiao Tong University
2020-2025
XinHua Hospital
2020
The use of dual-tracer contrast agents in clinical applications, such as sentinel lymph node (SLN) identification, offers significant advantages including enhanced accuracy, sensitivity, well comprehensive and multimodal visualization. In the current practice, SLNs are typically marked prior to surgical resection by multiple sequential injections two tracers, radioactive tracer methylene blue (MB) dye. This imposes physical psychological burden on patients medical staff. Surface-enhanced...
The phenotype of circulating tumor cells (CTCs) offers valuable insights into monitoring cancer metastasis and recurrence. While microfluidics presents a promising approach for capturing these rare in blood, the phenotypic profiling CTCs remains technically challenging. Herein, we developed nanoporous micropillar array chip enabling highly efficient capture situ analysis through enhanced tunable on-chip immunoaffinity binding. addresses fundamental limits fluidic mass transfer, surface...
Neoadjuvant chemotherapy (NAC) is a systemic and systematic regimen for breast cancer patients before surgery. However, NAC not effective everyone, the process excruciating. Therefore, accurate early prediction of efficacy essential clinical diagnosis treatment patients. In this study, novel convolutional neural network model with bimodal layer-wise feature fusion module (BLFFM) temporal hybrid attention (THAM) proposed, which uses multistage ultrasound images as input neoadjuvant in locally...
The heterogeneity of breast tumors might reflect biological complexity and provide prediction clues for the sensitivity treatment. This study aimed to construct a model based on tumor in magnetic resonance imaging (MRI) predicting pathological complete response (pCR) neoadjuvant chemotherapy (NAC). retrospective involved 217 patients with biopsy-confirmed invasive cancer who underwent MR before after NAC. Patients were randomly divided into training cohort validation at 1:1 ratio. images...
Background: Recently, the classification of HER2 status evolves from binary to ternary, and HER2-low expression may exhibit prognostic significance. We aimed investigate whether tumor is distinct HER2-zero or HER2-positive tumors, then develop a modified staging system (mNeo-Bioscore) that incorporates into Neo-Bioscore. Patients Methods: This cohort study was conducted using data prospective database on breast cancer patients between January 2014 February 2019. Results: Among 259 enrolled...
Objective: To evaluate the clinical characteristics and prognosis of gallbladder cancer (GBC) patients in China. Methods: This retrospective multicenter cohort study enrolled 3 528 consecutive GBC diagnosed between January 2010 to December 2017 15 hospitals from 10 provinces. There were 1 345 (38.12%) males 2 183 (61.88%) females.The age diagnosis was (63.7±10.8) years old (range: 26 99 old) .There 213 (6.04%) stage 0 Ⅰ, whereas 059 (30.02%) Ⅱ Ⅲ, 874 (53.12%) Ⅳ, 382 (10.83%) unavailable....
To investigate the association between lipid ratios and survival outcomes in patients with locally advanced breast cancer (LABC) undergoing neoadjuvant chemotherapy.
Temporal heterogeneity in human epidermal growth factor receptor 2 (HER2) status may be associated with the prognosis of breast cancer. We aimed to clarify relationship HER2-low transition during neoadjuvant therapy survival outcomes under new classification HER2 status.
Abstract [Background] The clinicopathological characteristics, pathological complete response and survival outcomes of HER2-low, HER2-zero HER2-positive breast cancers are yet to be elucidated in Chinese patients especially those administered neoadjuvant chemotherapy. [Methods] We retrospectively identified 259 with different HER2 statuses (zero, low positive) who underwent surgery as planned after chemotherapy from a prospectively maintained institutional cohort database Renji Hospital,...