Abstract: Titanium dioxide (TiO 2 ) nanoparticles are among the top five used in consumer products, paints, and pharmaceutical preparations. Given that exposure to such is mainly via skin inhalation, present study was conducted male Wistar albino rats ( Rattus norvegicus ). Our aim investigate effect of TiO on hepatic tissue an attempt understand their toxicity potential therapeutic diagnostic use. To effects liver tissue, 30 healthy were exposed at doses 63 mg, 126 252 mg per animal for 24...

A total of 1158 cats with feline upper respiratory tract infection were incorporated from twenty animal hospitals in Wuhan, China, April 2019 to 2022 investigate the epidemiology calicivirus (FCV), herpesvirus-1 (FHV-1), Mycoplasma felis (M. felis) and Chlamydia (C. for development a geographically-specific FCV vaccine reference prevalence risk factors infection. The 871 samples (75.2%) kittens younger than 12 months, which 693 males, 456 females. Among samples, 443 British shorthair cats,...

Azoxystrobin (AZX), also known as Amisida, is a widely used medication for treating and managing fungal diseases in agriculture.The hazardous effects of azoxystrobin on non-target organisms, particularly fish have generated significant attention its toxicological study since it penetrates aquatic environment from several locations.The toxicity experimental was investigated this using variety biomarkers including hematology, antioxidant enzymes, oxidative stress indicators, histopathological...

Gentamicin is an effective widely used antibiotic, but the risk of nephrotoxicity and oxidative damage limit its long-term use. Hence, current study aims to elucidate such hazardous effects. To achieve aim male Wistar albino rats (Rattus norvegicus) were exposed gentamicin investigate resultant blood chemical changes renal histological alterations. In comparison with control rats, produced outstanding tubular, glomerular interstitial alterations that included degeneration, necrosis,...

Quercetin is a naturally existing plant pigment belonging to the flavonoid group; it contained in wide range of vegetables and fruits. The accumulated evidence points potential uses quercetin protection some disease conditions. Lead one highly toxicant heavy metals that are widely spread environment implicated spectrum industries. No previous study has been reported evaluate effect on lead toxicity. Therefore, present was conducted elucidate aspects bioactivities regard its ability combat...

The present study focused on extracting green larvicides from extracts of the combination Foeniculum vulgare and Matricaria chamomilla using different solvents increasing polarity in a Soxhlet extractor evaluating their ovicidal, larvicidal, cytotoxic activities. most promising among all tested was hexane extract. ovicidal activity PH2 extract resulted significant (p < 0.05) decrease egg hatchability 95.00 ± 6.16% to 15 9.04% at doses ranging 62.5 500 µg/mL. larval mortality with ranged...

Silver nanoparticles (Ag NPs) are widely used in nanomedicine, pharmaceutical products, industry and other consumer products owing to their unique physiochemical properties with probable potential risk human health the ecosystems. The aim of this work was investigate in-life morphological effects, biochemical, histological histochemical alterations that might be induced by variable sizes Ag NPs hepatic, renal testicular tissues hypothesis nano-Ag could induce effects vital organs. Five...

The oral intake of alcohol has become a widespread concern due to its high risk body health. Therefore, our purpose in this study was reveal the antioxidant efficacies natural Commiphora myrrha on hepatotoxicity and oxidative stress induced by ethanol adult male rats, especially because these were not adequately revealed previous studies. We examined impacts C. Sprague Dawley rats orally treated with (500 mg/kg) alone or combination 40% (3 g/kg), daily for 30 days. results showed that...

Abstract The present study investigated the toxic action of acrylamide (ACR) and abrogative effect aqueous propolis extract on ACR-induced toxicity in male albino rats. Forty adult rats were randomly divided into four groups administered treatment doses orally by gavage. Control, treated with a physiological solution (5.0 ml/rat). ACR-treated group, ACR 25 mg/kg. + propolis, mg/kg 100 propolis. Propolis-treated period was 28 days, using gavage stomach tube. results showed that presence...

The study aimed to clarify the characteristics of black tea (BTE) and/or curcumin (CMN) against aflatoxin-B1 (AFB1). Forty eight adult male Sprague–Dawley rats were divided into groups. G1 was non-treated control. G2, G3, and G4 olive oil, BTE, CMN, respectively. G5 oil-dissolved AFB1 (25 µg/kg b.w). G6, G7, G8 along with BTE (2%), CMN (200 mg/kg b.w.), plus All treatments orally given for consecutive 90 days. After treatment period, sacrificed. Serobiochemical analysis histopathology showed...

Titanium dioxide nanoparticles (TiO2 NPs) are widely used in many commercial products, nanomedicine, agriculture, personal care different industries and pharmaceutical preparations with potential risk human health the environment. The current work was conducted to investigate renal damage that might be induced by acute toxicity TiO2 NPs. A total of 40 healthy male adult Wistar albino rats (Rattus norvegicus) were exposed NPs (126, 252, 378 mg/kg bw) for 24 48 h. Fresh portions kidneys from...

Silver nanoparticles (Ag NPs) are invested in various sectors and becoming more persistent our ambient environment with potential risk on health the ecosystems. The current study aims to investigate histological, histochemical ultrastructural hepatic changes that might be induced by 10 nm silver nanomaterials. Male mice (BALB/C) were exposed for 35 injections of daily dose Ag NPs (2 mg/kg). Liver tissues subjected examination light electron microscopy alterations. Exposure Kupffer cells...

The study objective was to evaluate Allium sativum's potential and Nigella Sativa's combination's reduce aluminum toxicity return the normal state. In present study, a hundred albino rats were randomly divided into five equal groups. first group used as control group; other four groups exposed 1,600 ppm. second only; third fourth treated with sativum 5% sativa 5%, respectively, while fifth mix of 2.5% for 8th weeks. After 8 weeks, administration stopped, three 2.5%, respectively. (continued...

Abstract A popular polyherbal formulation prepared from five plants (PHF5) may have anticancer effects. However, there is a lack of adequate scientific evidence. We assessed the anticancer, antioxidant, and acute toxicity effects PHF5. Cancer cells were treated with 0 to 300 μg/mL PHF5 extract. Established assays used assess cytotoxicity, apoptosis, radical scavenging activities. In study, mice administered single oral dose (2,000 mg/kg) PHF5, biochemical histopathological parameters...

Copper oxide nanomaterials are used in many biomedical, agricultural, environmental, and industrial sectors with potential risk to human health the environment. The present study was conducted determine renal ultrastructural damage caused by 25 nm CuO nanoparticles tissues. Adult healthy male Wister Albino rats (Rattus norvegicus) were administered 35 intraperitoneal injections of (2 mg/kg). Ultrastructural changes evaluated using transmission electron microscopy techniques. tissues...

Titanium dioxide nanoparticles (TiO2 NPs) have novel application and are used in many household application, nanomedicine, agriculture, industries pharmaceutical products. These applications may be accompanied with potential risk human health the ecosystems. The current study was carried out to find acute damage that might induced by TiO2 NPs heart testis. Three groups of Wistar albino rats (Rattus norvegicus) were subjected a single dose (126, 252, 378 mg/kg bw). Cardiac testicular biopsies...

Jatropha variegata (family, Euphorbiaceae) is native to Yemen, where it commonly known as the Ebki shrub. The fruits of plant are traditionally ingested by local women a natural method contraception. This study was undertaken investigate phytochemical content methanol extract J. and evaluate its antifertility potential.Isolation chemical constituents performed chromatographic techniques, structures these compounds were identified spectroscopy. activity assessed in two experimental rat models...

Abstract Background: Melatonin is a peptide neurohormone naturally synthesized in the brain by pineal gland. The basic function of melatonin related to causation and regulation sleep–wake cycle (circadian cycle). Cadmium (Cd) hazardous heavy metal its toxic effects induce extensive tissue damage. present study was undertaken elucidate efficiency exogenous attenuating Cd-induced oxidative stress. Methods: experimental rats were allotted into four groups ( n = 20), designated as untreated...