- Analytical chemistry methods development
- Mass Spectrometry Techniques and Applications
- Mercury impact and mitigation studies
- Advanced Proteomics Techniques and Applications
- Radioactive element chemistry and processing
- Atmospheric chemistry and aerosols
- Coral and Marine Ecosystems Studies
- Per- and polyfluoroalkyl substances research
- Trace Elements in Health
- Ion-surface interactions and analysis
- Luminescence Properties of Advanced Materials
- Cryospheric studies and observations
- Heavy metals in environment
- Biosensors and Analytical Detection
- Geology and Paleoclimatology Research
- Marine and coastal plant biology
- Marine and Offshore Engineering Studies
- Medical Imaging Techniques and Applications
- Radiopharmaceutical Chemistry and Applications
- Advanced oxidation water treatment
- Nanoplatforms for cancer theranostics
- Corrosion Behavior and Inhibition
- Marine Biology and Ecology Research
- Protease and Inhibitor Mechanisms
- Advanced Memory and Neural Computing
University of Graz
2022-2025
University of Technology Sydney
2018-2023
Sanford Broadway Medical Center
2019
University of Münster
2015-2018
Climate change, in tandem with localised stressors, continues to drive global declines coral cover worldwide. Identifying where and how corals survive present day extreme environments, characterised by suboptimum abiotic conditions, has become a key tool better resolve stress tolerance turn future reef trajectories. Whilst several forming species routinely extend their ecological niche into whether have distinct biogeochemical reflected unique elementomes (the stoichiometry quantity of...
Elemental bio-imaging using the technological advances of ICP-QQQ-MS.
Human zinc deficiency increases susceptibility to bacterial infection. Although supplementation therapies can reduce the impact of disease, molecular basis for protection remains unclear. Streptococcus pneumoniae is a major cause pneumonia, which prevalent in regions deficiency. We report that dietary levels dictate outcome S. infection murine model. Dietary restriction impacts tissue with distribution post-infection altered, and virulence enhanced. activation infiltration phagocytic cells...
A data processing platform was developed for the analysis of single particle and cell ICP-MS sets. All functions are embedded in a GUI enable signal recognition, accumulation calibration via dedicated pathways filters.
Abstract Understanding the microscopic variability of impurities in glacier ice on a quantitative level has importance for assessing preservation paleoclimatic signals and enables study macroscopic deformational as well dielectric properties. Two‐dimensional imaging via laser‐ablation‐inductively‐coupled‐plasma‐mass‐spectrometry (LA‐ICP‐MS) can provide key insight into localization ice. So far, these findings are mostly qualitative gaining insights remains challenging. Recent advances...
The unique properties of per- and polyfluoroalkyl substances (PFAS) have led to their extensive use in consumer products, including ski wax. Based on the risks associated with PFAS, align PFAS regulations, international federation (FIS) implemented a ban products containing "C
The analysis of natural and anthropogenic nanomaterials (NMs) in the environment is challenging requires methods capable to identify characterise structures on nanoscale regarding particle number concentrations (PNCs), elemental composition, size, mass distributions. In this study, we employed single inductively coupled plasma-mass spectrometry (SP ICP-MS) investigate occurrence NMs Melbourne area (Australia) across 63 locations. Poisson statistics were used discriminate between signals from...
Two strategies can improve figures of merit in ICP-ToF-MS: the use a Bradbury–Nielson gate to duty cycles and, post-analysis accumulation isotopic signals from polyisotopic elements.
Abstract Diagnosis and localization of bacterial infections remains a significant clinical challenge. Harnessing bacteria‐specific metabolic pathways, such as the maltodextrin transport mechanism, may allow specific imaging small or hidden colonies. This requires that intrabacterial tracer accumulation provided by transporter is matched high serum stability molecule. Herein, radiolabeled maltodextrins varying chain lengths with free nonreducing/reducing ends are reported their behavior...
Raw intensities obtained from the ablation of mould-prepared gelatine.
Speciation analysis of Gd-based MRI contrast agents in fresh and oceanic waters employing an automatised micro-solid phase extraction method HILIC-ICP-MS detection operating increased mass bandpass.
This work introduces novel and universal workflows for the analysis of intact proteins by capillary electrophoresis presents guidelines targeted selection appropriate background electrolytes (BGEs) consideration target proteins' isoelectric point (pI). The suitability neutral dimethyl polysiloxane (PDMS) capillaries with dynamic coatings cationic cetyltrimethylammonium bromide (CTAB) or anionic sodium dodecyl sulfate (SDS), bare fused silica (BFS) were systematically evaluated histidine...
Nanoparticles are produced at accelerating rates, increasingly integrated into scientific and industrial applications, widely discharged the environment. Analytical techniques required to characterize parameters such as particle number concentrations, mass size distributions, molecular elemental compositions, stability. This is not only relevant investigate their utility for various or medical applications controlling manufacturing processes but also assess toxicity environmental fate....
Cetaceans are known to accumulate very high levels of mercury (Hg) and unlike fish species, most the is not present as methylmercury (MeHg) but instead inorganic Hg. It has been suggested this a result detoxification process which involves sequestering Hg by Se-containing proteins, concluding with formation HgSe nanoparticles. However, their elemental compositions besides Se, well genesis unknown. We applied asymmetric flow-field flow fractionation - multiangle laser light scattering (AF4...
Elements are the basis of life on Earth, whereby organisms essentially evolved chemical substances that dynamically interact with each other and their environment. Determining species elemental quotas (their elementome) is a key indicator for success across environments different resource availabilities. Elementomes remain undescribed functionally diverse dinoflagellates within family Symbiodiniaceae includes coral endosymbionts. We used dry combustion ICP-MS to assess whether (ten isolates...
Non-targert screening and characterisation of nanoparticles in spirits.
Hg : Se atomic ratios in NPs formed whales were constant with increasing particle size. The also incorporated other metals (Cd, Sn) indicating that this process may not act exclusively as a MeHg detoxification process.