David Clases

ORCID: 0000-0003-3880-9385
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About
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Research Areas
  • Analytical chemistry methods development
  • Mass Spectrometry Techniques and Applications
  • Mercury impact and mitigation studies
  • Advanced Proteomics Techniques and Applications
  • Radioactive element chemistry and processing
  • Atmospheric chemistry and aerosols
  • Coral and Marine Ecosystems Studies
  • Per- and polyfluoroalkyl substances research
  • Trace Elements in Health
  • Ion-surface interactions and analysis
  • Luminescence Properties of Advanced Materials
  • Cryospheric studies and observations
  • Heavy metals in environment
  • Biosensors and Analytical Detection
  • Geology and Paleoclimatology Research
  • Marine and coastal plant biology
  • Marine and Offshore Engineering Studies
  • Medical Imaging Techniques and Applications
  • Radiopharmaceutical Chemistry and Applications
  • Advanced oxidation water treatment
  • Nanoplatforms for cancer theranostics
  • Corrosion Behavior and Inhibition
  • Marine Biology and Ecology Research
  • Protease and Inhibitor Mechanisms
  • Advanced Memory and Neural Computing

University of Graz
2022-2025

University of Technology Sydney
2018-2023

Sanford Broadway Medical Center
2019

University of Münster
2015-2018

Climate change, in tandem with localised stressors, continues to drive global declines coral cover worldwide. Identifying where and how corals survive present day extreme environments, characterised by suboptimum abiotic conditions, has become a key tool better resolve stress tolerance turn future reef trajectories. Whilst several forming species routinely extend their ecological niche into whether have distinct biogeochemical reflected unique elementomes (the stoichiometry quantity of...

10.1016/j.scitotenv.2025.179455 article EN cc-by-nc-nd The Science of The Total Environment 2025-04-25

Elemental bio-imaging using the technological advances of ICP-QQQ-MS.

10.1039/c5ja00293a article EN cc-by Journal of Analytical Atomic Spectrometry 2015-09-07

Human zinc deficiency increases susceptibility to bacterial infection. Although supplementation therapies can reduce the impact of disease, molecular basis for protection remains unclear. Streptococcus pneumoniae is a major cause pneumonia, which prevalent in regions deficiency. We report that dietary levels dictate outcome S. infection murine model. Dietary restriction impacts tissue with distribution post-infection altered, and virulence enhanced. activation infiltration phagocytic cells...

10.1371/journal.ppat.1007957 article EN cc-by PLoS Pathogens 2019-08-22

A data processing platform was developed for the analysis of single particle and cell ICP-MS sets. All functions are embedded in a GUI enable signal recognition, accumulation calibration via dedicated pathways filters.

10.1039/d1ja00297j article EN Journal of Analytical Atomic Spectrometry 2021-01-01

Abstract Understanding the microscopic variability of impurities in glacier ice on a quantitative level has importance for assessing preservation paleoclimatic signals and enables study macroscopic deformational as well dielectric properties. Two‐dimensional imaging via laser‐ablation‐inductively‐coupled‐plasma‐mass‐spectrometry (LA‐ICP‐MS) can provide key insight into localization ice. So far, these findings are mostly qualitative gaining insights remains challenging. Recent advances...

10.1029/2023gc011425 article EN cc-by Geochemistry Geophysics Geosystems 2024-04-01

The unique properties of per- and polyfluoroalkyl substances (PFAS) have led to their extensive use in consumer products, including ski wax. Based on the risks associated with PFAS, align PFAS regulations, international federation (FIS) implemented a ban products containing "C

10.1016/j.aca.2024.342754 article EN cc-by Analytica Chimica Acta 2024-05-21

The analysis of natural and anthropogenic nanomaterials (NMs) in the environment is challenging requires methods capable to identify characterise structures on nanoscale regarding particle number concentrations (PNCs), elemental composition, size, mass distributions. In this study, we employed single inductively coupled plasma-mass spectrometry (SP ICP-MS) investigate occurrence NMs Melbourne area (Australia) across 63 locations. Poisson statistics were used discriminate between signals from...

10.1007/s00216-022-04052-0 article EN cc-by Analytical and Bioanalytical Chemistry 2022-04-28

Two strategies can improve figures of merit in ICP-ToF-MS: the use a Bradbury–Nielson gate to duty cycles and, post-analysis accumulation isotopic signals from polyisotopic elements.

10.1039/d3ja00288h article EN cc-by Journal of Analytical Atomic Spectrometry 2023-11-30

Abstract Diagnosis and localization of bacterial infections remains a significant clinical challenge. Harnessing bacteria‐specific metabolic pathways, such as the maltodextrin transport mechanism, may allow specific imaging small or hidden colonies. This requires that intrabacterial tracer accumulation provided by transporter is matched high serum stability molecule. Herein, radiolabeled maltodextrins varying chain lengths with free nonreducing/reducing ends are reported their behavior...

10.1002/cmdc.201700543 article EN ChemMedChem 2017-11-30

Speciation analysis of Gd-based MRI contrast agents in fresh and oceanic waters employing an automatised micro-solid phase extraction method HILIC-ICP-MS detection operating increased mass bandpass.

10.1039/d0ja00493f article EN Journal of Analytical Atomic Spectrometry 2021-01-01

This work introduces novel and universal workflows for the analysis of intact proteins by capillary electrophoresis presents guidelines targeted selection appropriate background electrolytes (BGEs) consideration target proteins' isoelectric point (pI). The suitability neutral dimethyl polysiloxane (PDMS) capillaries with dynamic coatings cationic cetyltrimethylammonium bromide (CTAB) or anionic sodium dodecyl sulfate (SDS), bare fused silica (BFS) were systematically evaluated histidine...

10.1039/d2an00474g article EN The Analyst 2022-01-01

Nanoparticles are produced at accelerating rates, increasingly integrated into scientific and industrial applications, widely discharged the environment. Analytical techniques required to characterize parameters such as particle number concentrations, mass size distributions, molecular elemental compositions, stability. This is not only relevant investigate their utility for various or medical applications controlling manufacturing processes but also assess toxicity environmental fate....

10.1021/acs.analchem.3c04657 article EN cc-by Analytical Chemistry 2024-05-14

Cetaceans are known to accumulate very high levels of mercury (Hg) and unlike fish species, most the is not present as methylmercury (MeHg) but instead inorganic Hg. It has been suggested this a result detoxification process which involves sequestering Hg by Se-containing proteins, concluding with formation HgSe nanoparticles. However, their elemental compositions besides Se, well genesis unknown. We applied asymmetric flow-field flow fractionation - multiangle laser light scattering (AF4...

10.26434/chemrxiv-2024-lh431 preprint EN cc-by-nc 2024-01-24

Elements are the basis of life on Earth, whereby organisms essentially evolved chemical substances that dynamically interact with each other and their environment. Determining species elemental quotas (their elementome) is a key indicator for success across environments different resource availabilities. Elementomes remain undescribed functionally diverse dinoflagellates within family Symbiodiniaceae includes coral endosymbionts. We used dry combustion ICP-MS to assess whether (ten isolates...

10.1186/s12870-022-03512-0 article EN cc-by BMC Plant Biology 2022-04-09

Non-targert screening and characterisation of nanoparticles in spirits.

10.1039/d3ja00253e article EN cc-by Journal of Analytical Atomic Spectrometry 2023-01-01

Hg : Se atomic ratios in NPs formed whales were constant with increasing particle size. The also incorporated other metals (Cd, Sn) indicating that this process may not act exclusively as a MeHg detoxification process.

10.1039/d3en00886j article EN cc-by Environmental Science Nano 2024-01-01
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