Abstract The decades-long gap in antibiotic discovery has led to a significant health crisis due antimicrobial resistance (AMR). bacterial genus Xenorhabdus , which forms symbiotic relationships with the soil nematode Steinernema are known secrete variety of compounds potential effectiveness against AMR. These primarily bio-synthesized by non-ribosomal peptide synthetases (NRPS) and polyketide synthetase (PKS) genes. In this study, we report that X. szentirmaii produces high levels activity...

The decades-long gap in antibiotic discovery has led to a significant health crisis due antimicrobial resistance (AMR). bacterial genus Xenorhabdus , which forms symbiotic relationships with the soil nematode Steinernema are known secrete variety of compounds potential effectiveness against AMR. These primarily bio-synthesized by non-ribosomal peptide synthetases (NRPS) and polyketide synthase (PKS) genes. In this study, we report that X. szentirmaii produces high levels activity during...

Aneuploidies are a major cause of perinatal morbidity and mortality. Therefore, it is the most common indication for invasive prenatal diagnosis. Initially, screening aneuploidies started with maternal age risk estimation. Later on, serum testing biochemical markers ultrasound were added. Women detected to be at high-risk offered testing. New research now focusing on non-invasive using cell-free fetal DNA in circulation. The advantage this technique ability reduce miscarriage associated...

Pre-eclampsia is one of the leading causes high rates maternal and perinatal mortality morbidity. Pathophysiology pre-eclampsia still obscure. Currently, there are no screening tests for that reliable, valid, economical. Parameters oxidative stress could be early markers endothelial dysfunction predates clinical pre-eclampsia.This study was to ceruloplasmin in nulliparous women as marker lipid profile evaluate their value prediction pre-eclampsia.Prospective observational study. 306 had...

OBJECTIVES: Suppressed immune system and physiological changes in pregnancy put pregnant women vulnerable to various viral diseases. Various studies have reported adverse outcomes SARS-CoV-2 infection. This study aimed evaluate the maternal fetal affected pregnancies at our set up. STUDY DESIGN: It was a prospective cohort conducted tertiary care Army Hospital, India. The first 50 cases of SARS CoV-2 positive 144 suspected that were found negative, received managed separate up, during period...

OBJECTIVE: The ongoing COVID-19 pandemic is causing widespread concern, fear, stress, anxiety, and depression throughout the population worldwide. Pregnant women, being a vulnerable group, are grossly affected by these changing environmental scenarios. spread of Corona Virus infection itself subsequent nation-wide lockdown in India, just like many other countries, has caused serious impact on antenatal patients. objective this study was to bring out specific concerns pregnant women during...

An alarming rate of adverse perinatal outcomes as well maternal deaths has been reported worldwide during this pandemic. It would be prudent to start thinking on the lines acute or chronic intrauterine fetal hypoxia due placental microvascular pathology villitis caused by severe respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection. Autopsy studies deceased patients with COVID-19 have revealed presence diffuse pulmonary alveolar damage, thrombosis, and injuries. is expected that similar...

Background: Preterm premature rupture of membrane (PPROM) and (PROM) are associated with various maternal neonatal complications. Management guidelines regarding before labour is still controversial. The study was carried out to determine the outcomes membranes beyond 34 weeks gestation.Methods: It a prospective observational in tertiary care teaching hospital for period one year. All pregnant women included study. After establishment diagnosis membranes, antibiotics were started all them...

OBJECTIVES: Low levels of pregnancy-associated plasma protein-A in pregnant women linked to unhealthy placentation and a spectrum maternal fetal complications. Its assessment as single biomarker has the potential identify high-risk pregnancies. This prospective observational study was conducted find correlation between low first trimester pregnancy with various obstetric outcomes establish if it can be used for counseling couples. STUDY DESIGN: The at Base Hospital, Delhi Cantt. Maternal...

OBJECTIVES: In India, despite the high prevalence of vitamin B12 (vit B12) deficiency, current public health policy focuses solely on iron and folic acid supplementation as a measure to prevent anaemia. Vit is an important cofactor for enzymatic reactions related DNA synthesis, folate, cell metabolism. While folate deficiency has been acknowledged in not only prevention neural tube defects other adverse pregnancy outcomes, effects low vit status have well defined. It becoming recognized that...

Background: Fetal distress is an important indication for emergency caesarean deliveries. The objective of this study to identify the antenatal and intrapartum risk factors in caesareans done non-reassuring fetal status compare with patients who underwent other indications.Methods: It was a retrospective data collected from labour room records tertiary care hospital. Patients undergoing were cases remaining controls. Data statistically analyzed.Results: There 5184 deliveries during period...

Thyroid storm in pregnancy is a rare life threatening emergency, with very high maternal and perinatal mortality morbidity. Here we present an unusual case of 30 year-old G2P1L1 woman, known post caesarean hyperthyroidism who presented severe preeclampsia on second op day developed thyroid storm. Early recognition timely institution appropriate management resulted good outcome this case.

Preterm birth is associated with significant perinatal morbidity and mortality. Spontaneous preterm accounts for upto 75% of all births. A number maternal fetal characteristics have been birth. With better understanding the pathophysiology birth, various biochemical markers studied extensively to predict efficiently so as intervene appropriately timely in cases that would benefit from treatment. This paper provides a summary current literature on use predicting spontaneous symptomatic high...

Background: Caesarean delivery is one of the most common operations performed worldwide. Maternal morbidity and risk blood transfusion increased greatly with caesarean compared that vaginal delivery. Aims: This study was carried out to evaluate loss requirement in patients undergoing section. Materials methods: A prospective observational a peripheral military hospital, India where 173 women underwent section data were obtained on age, parity, gestational type (elective/ emergency),...

Transverse vaginal septum is a rare cause of genital outflow tract obstruction. It results from incomplete fusion/recanalization between the components mullerian ducts and urogenital sinus. The varies in thickness may be present anywhere along vagina, although most are found upper mid-vagina. A complete primary amenorrhoea several short term long sequelae including endometriosis infertility. We case 12-year old girl who presented with intermittent, colicky abdominal pain. She had undergone...

Background: Controlled ovarian hyper stimulation (COH) using different agents with intrauterine insemination (IUI) are known treatment for infertility. Endometrial thickness (ET) is one of the predicting factors clinical pregnancy along other parameters. Many studies have been done in past to find affecting growth and maturity endometrium women IUI, but indigenous Indian regarding its relation were either limited or results unclear.Methods: A Prospective observational study was undertaken...

Backround: Although neonatal morbidity and mortality rates are fallen in recent decades, the prevalence of preterm deliveries has increased especially late births. Late at risk various complications compared to term deliveries.This study was carried out identify maternal characteristics co-morbidites found with births feto-maternal outcome terms indication delivery, route Apgar score NICU admissions.Methods: A retrospective conducted a tertiary care teaching hospital Indian armed forces...

IntroductIonAntenatal urinary tract dilation (UTD) in the fetus presents a diagnostic quandary with prognosis ambiguity because it is related to numerous etiologies, uropathies, and as component of an uncountable wide range syndromes.The prevalence UTD ranges from 1 2%. The majority fetuses are physiologic or transient resolve on their own. 2 fundamental goal detection distinguish between physiological pathological types so that utero postnatal treatment advice may be provided.Ranked highest...

Primary ovarian pregnancy is rare and accounts for only 0.5%to 3% of all ectopic pregnancies. The diagnosis often made intraoperatively confirmed histopathologically. We present a case ruptured primary who presented to the emergency services in shock was initially diagnosed as tubal ectopic. However at laparotomy clinical findings suggested which on histopathology. discussion highlights difficulty pre operative diagnosis, role conservative surgery importance histopathology accurate this condition.