Kun He

ORCID: 0000-0003-3903-0955
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About
Contact & Profiles
Research Areas
  • Air Quality and Health Impacts
  • Atmospheric chemistry and aerosols
  • Antibiotic Resistance in Bacteria
  • Toxic Organic Pollutants Impact
  • Escherichia coli research studies
  • Thermochemical Biomass Conversion Processes
  • Vehicle emissions and performance
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Bacteriophages and microbial interactions
  • Energy and Environment Impacts
  • Bacterial Genetics and Biotechnology
  • Air Quality Monitoring and Forecasting
  • Climate Change and Health Impacts
  • Spinal Dysraphism and Malformations
  • Enterobacteriaceae and Cronobacter Research
  • Catalytic Processes in Materials Science
  • Coal Properties and Utilization
  • Fire dynamics and safety research
  • Plant Pathogenic Bacteria Studies
  • Nanoparticles: synthesis and applications
  • COVID-19 impact on air quality
  • Fetal and Pediatric Neurological Disorders
  • Cerebrospinal fluid and hydrocephalus
  • Immune Response and Inflammation
  • Dermatologic Treatments and Research

Henan Agricultural University
2022-2025

China-Japan Friendship Hospital
2024

Peking University
2024

Affiliated Hospital of North Sichuan Medical College
2024

Xian Yang Central Hospital
2024

Xi'an Jiaotong University
2020-2024

New York University Press
2019

Cambridge University Press
2019

Ministry of Science and Technology
2018

Jiangsu Academy of Agricultural Sciences
2018

Tropospheric ozone (O3) pollution has been becoming prominent in North China Plain (NCP) since last decade. In order to clarify the source contribution and formation mechanism of O3, critical precursors volatile organic compounds (VOCs) were measured with both on-line off-line methods Luoyang City summer 2019. The concentrations nitrogen oxides (NOx, sum NO NO2) O3 simultaneously monitored. Fifty-seven VOCs U.S. Photochemical Assessment Monitoring Station (PAMS) showed daily a range 14.5 ±...

10.1016/j.envint.2020.106279 article EN cc-by Environment International 2020-12-01

H-NS is a histone-like nucleoid-structuring protein that regulates gene expressions, particularly acquired foreign genes, however, little known about whether can modulate bacterial susceptibility by regulating its intrinsic genes. The hns-deleted mutant EΔhns, the hns-complemented strain EΔhns/phns and hns-overexpressed E/phns were derivatives of Escherichia coli ATCC 25922, which assessed broth microdilution method time-kill curves assays. We found MICs for EΔhns against gentamicin amikacin...

10.3389/fvets.2025.1534498 article EN cc-by Frontiers in Veterinary Science 2025-02-06

Coal combustion emits a large amount of PM2.5 (particulate matters with aerodynamic diameters less than 2.5 μm) and causes adverse damages to the cardiovascular system. In this study, emissions from anthracite bitumite were examined. Red mud (RM) acts as an additive is mixed in coal briquettes content 0-10% single variable demonstrate reduction emissions. Burnt regulated chamber, 10% RM-containing showed 52.3 18.6% PM2.5, respectively, compared their chunk coals. Lower cytotoxicity (in terms...

10.1021/acs.est.0c02236 article EN Environmental Science & Technology 2020-11-03

Intermediate volatility organic compounds (IVOCs) are important precursors to secondary aerosols (SOAs), but they often neglected in studies concerning SOA formation. This study addresses the significant issue of IVOCs emissions Qinghai-Tibetan plateau (QTP), where solid fuels extensively used under incomplete combustion conditions for residential heating and cooking. Our field measurement data revealed an emission factor total (EFIVOCs) ranging from 1.56 ± 0.03 9.97 3.22 g/kg various...

10.1021/acs.est.4c02618 article EN Environmental Science & Technology 2024-06-12

Methoxyphenols and nitroaromatic compounds (NACs) have strong atmospheric radiative forcing effects adverse on human health. They are emitted from the incomplete combustion of solid fuels secondarily formed through photochemical reactions. Here, an on-site study was conducted to determine primary emission secondary formation particulate phase products a variety potential aerosol mass-oxidation flow reactor. Emission factors for total quantified methoxyphenols NACs (i.e., EF∑Methoxyphenols...

10.1021/acs.est.3c04370 article EN Environmental Science & Technology 2023-09-14

Extended-spectrum-β-lactamases (ESBLs)-producing Escherichia coli conferred resistance to most of β-lactams, except for carbapenems. To date, the transmission mechanism blaCTX-M, as common ESBLs subtype, in E. has received sustained attention around worldwide, but research on pathogenicity blaCTX-M-bearing is still scarce. The aims this study were discern spread characteristics ColV (encoding colicin V) plasmids blaCTX-M-positive coli. multi-drug traits, phylogroups and plasmid profilings...

10.1016/j.psj.2024.103631 article EN cc-by-nc-nd Poultry Science 2024-03-07

PM2.5 (particulate matter with aerodynamic diameter ≤ 2.5 μm) is a well-known cytotoxic pollutant that capable to induce severe intracellular oxidative stress while the underlying mechanisms remain unclear. Herein, 4 types of derived from solid fuel burning were selected as stimuli in A549 cells exposure model evaluate their effects on and inflammatory responses. Although resulting different responses cell viability, all exhibited over 50 % higher than control group, expression reactive...

10.1016/j.envint.2022.107674 article EN cc-by Environment International 2022-12-01

Pellino 1 positively regulates Toll-like receptor 4 signaling by regulating tumor necrosis factor receptor-associated 3 (TRAF3) degradation and is suppressed with the induction of endotoxin tolerance. However, role TRAF3 in tolerance largely unknown. In this study, we found that lipopolysaccharide (LPS) stimulation decreased TARF3 protein expression mouse Kupffer cells (KCs) liver tissues, whereas tolerization abrogated effect. Degradative K48-linked ubiquitination cytoplasmic translocation...

10.1093/infdis/jiw279 article EN The Journal of Infectious Diseases 2016-07-04

Hypertrophic scarring is a common proliferative disorder of dermal fibroblasts characterized by collagen overproduction and excessive deposition extracellular matrix (ECM). There no consensus about the best therapeutics to produce complete permanent improvement scars with few side effects. To investigate therapeutic effects oleanolic acid (OA) on hypertrophic explore possible mechanism action involved, rabbit ear model was established. OA (2.5%, 5%, 10%) given once daily for 28 consecutive...

10.1155/2012/837581 article EN Evidence-based Complementary and Alternative Medicine 2012-01-01

Air pollutants from the incomplete combustion of rural solid fuels are seriously harmful to both air quality and human health. To quantify health effects different fuel-stove combinations, gas particle partitioning twenty-nine species polycyclic aromatic hydrocarbons (PAHs) emitted seven combinations were examined in this study, benzo (a) pyrene toxicity equivalent (BaPeq) cancer risks estimated accordingly. The results showed that phase PAHs (accounting for 68-78% total PAHs) had higher...

10.3390/toxics11010080 article EN cc-by Toxics 2023-01-15

In Chinese zoos, there are usually specially designed bird parks, similar to petting that allow children and adults interact with diverse birds. However, such behaviors present a risk for the transmission of zoonotic pathogens. Recently, we isolated eight strains Klebsiella pneumoniae identified two blaCTX-M-positive from 110 birds, including parrots, peacocks, ostriches, using anal or nasal swabs in park zoo China. There, K. LYS105A was obtained diseased peacock chronic respiratory diseases...

10.1128/aem.01764-22 article EN Applied and Environmental Microbiology 2023-02-21
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