A5082227958- Adenosine and Purinergic Signaling
- Cardiac Structural Anomalies and Repair
- Tissue Engineering and Regenerative Medicine
- Obesity and Health Practices
- Interprofessional Education and Collaboration
- Peptidase Inhibition and Analysis
- Dietetics, Nutrition, and Education
- Mechanical Circulatory Support Devices
- Congenital heart defects research
- Pluripotent Stem Cells Research
- Hippo pathway signaling and YAP/TAZ
- Cancer Cells and Metastasis
- Long-Term Effects of COVID-19
- Nerve injury and regeneration
- S100 Proteins and Annexins
- Signaling Pathways in Disease
- Dental Education, Practice, Research
- Innovative Teaching Methods
- Fuel Cells and Related Materials
- Diversity and Career in Medicine
- Medical Education and Admissions
- Neurological Complications and Syndromes
- Cancer Mechanisms and Therapy
- Vitamin K Research Studies
- Cancer Immunotherapy and Biomarkers
Touro University California
2023-2024
Clovis Community College
2023
University of California, Riverside
2023
West Coast University
2023
A.T. Still University
2021-2022
San Diego State University
2016-2020
University of Rhode Island
2020
University of North Carolina at Chapel Hill
2020
Hospital General Universitario Gregorio Marañón
2018
Centro de Investigación Biomédica en Red
2018
The relative actions and synergism between distinct myocardial-derived stem cell populations remain obscure. Ongoing debates on optimal population(s) for treatment of heart failure prompted implementation a protocol isolation multiple from single myocardial tissue sample to develop new insights achieving regeneration.Establish robust cardiac culture consistently generate 3 human biopsy.Isolation endogenous was performed samples routinely discarded during implantation left ventricular assist...
Senescence-associated dysfunction deleteriously affects biological activities of human c-Kit+ cardiac progenitor cells (hCPCs), particularly under conditions in vitro culture. In comparison, preservation self-renewal and decreases mitochondrial reactive oxygen species (ROS) are characteristics murine CPCs vivo that reside within hypoxic niches. Recapitulating niche tension ∼1% O2 for expansion hCPCs rather than typical normoxic cell culture (21% ) could provide significant improvement...
Importance Diversity is an essential element of effective health care system. A key to developing a diverse workforce establishing student population in professions programs. Objective To examine the diversity students Doctor Medicine (MD), Osteopathic (DO), Dental Surgery (DDS), (DMD), and Pharmacy (PharmD) programs with emphasis on trends underrepresented minoritized groups (American Indian or Alaska Native, Black African American, Hispanic Latino, Native Hawaiian Other Pacific Islander)...
Biological significance of c-Kit as a cardiac stem cell marker and role(s) c-Kit+ cells in myocardial development or response to pathological injury remain unresolved because varied discrepant findings. Alternative experimental models are required contextualize reconcile discordant published observations biology provide meaningful insights regarding clinical relevance signaling for translational therapy.The main objectives this study follows: demonstrating through combined studies both human...
The ongoing COVID-19 outbreak has caused devastating mortality and posed a significant threat to public health worldwide. Despite the severity of this illness 2.3 million worldwide deaths, disease mechanism is mostly unknown. Previous studies that characterized differential gene expression due SARS-CoV-2 infection lacked robust validation. Although vaccines are now available, effective treatment options still out reach.
Autologous stem cell therapy using human c-Kit+ cardiac progenitor cells (hCPCs) is a promising therapeutic approach for treatment of heart failure (HF). However, hCPCs derived from aged patients with HF genetic predispositions and comorbidities chronic diseases exhibit poor proliferative migratory capabilities, which impair overall reparative potential injured myocardium. Therefore, empowering functionally compromised proregenerative molecules ex vivo crucial improving the outcome in HF.To...
Telomere attrition in cardiomyocytes is associated with decreased contractility, cellular senescence, and up-regulation of proapoptotic transcription factors. Pim1 a cardioprotective kinase that antagonizes the aging phenotype delays senescence by maintaining telomere length, but mechanism remains unknown. Another pathway responsible for regulating length transforming growth factor beta (TGFβ) signalling where inhibiting TGFβ maintains length. The relationship between has not been explored....
Autologous cardiac progenitor cell (CPC) therapy is a promising approach for treatment of heart failure (HF). There an unmet need to identify inherent deficits in aged/diseased human CPCs (hCPCs) derived from HF patients the attempts augment their regenerative capacity prior use clinical setting. Here we report significant functional correlations between phenotypic properties hCPCs isolated biopsies patients, parameters and expression P2Y14 purinergic receptor (P2Y14 R), crucial detector...
Background Poor nutrition and lifestyle choices are major contributors to the development progression of various chronic diseases. Enhancing patients' awareness healthy habits by interprofessional healthcare teams can play a significant role in tackling many diseases, particularly underserved communities with inequitable access educational opportunities. However, professionals not adequately prepared provide effective, culturally competent coaching due lack emphasis on these topics curricula...
Farid's goal is to establish an independent research career with emphasis on studying cellular responses extracellular nucleotide stress signals in the myocardium and developing novel translational approaches for treatment of HF.In his spare time, Farid enjoys attending lectures Islamic studies, playing soccer, traveling friends, family, 6-month-old baby.
Heart failure (HF) is a leading cause of death in the US due to limited capability adult mammalian heart regenerate after myocardial infarction (MI). Autologous stem cell therapy holds promise for promoting regeneration injured but cells derived from diseased organs exhibit poor proliferative, migratory and survival capabilities. Empowering cardiac-derived progenitor (CPC) with prosurvival genes has been attempted. However, molecular mechanisms by which detect stress signals subsequently...
Heart failure (HF) is a leading cause of death due to limited regenerative capacity adult mammalian heart following injury. Autologous stem cell therapy holds promise for promoting cardiac regeneration. However, cells derived from aged/diseased organs exhibit poor growth and survival capabilities. Empowering progenitor (CPC) with prosurvival genes has been attempted. Nonetheless, the molecular mechanisms by which initially detect stress signals stimulate appropriate responses are poorly...
Objective: This study aims to assess how near-peer tutoring impacts the wellness of students in their first professional year pharmacy school.Methods: An electronic survey was emailed each student school.The validated Rosenberg Self-Esteem scale measuring emotional and New General Self-Efficacy intellectual wellness, were included.Other data collected from this included number sessions attended a numerical score student's self-reported academic performance.Results: Students that improved...