A5113086901- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Inflammatory Myopathies and Dermatomyositis
- Analytical Chemistry and Chromatography
- Asthma and respiratory diseases
- Systemic Sclerosis and Related Diseases
- Analytical chemistry methods development
- Urinary Bladder and Prostate Research
- Advanced Chemical Sensor Technologies
- Lung Cancer Diagnosis and Treatment
- Salivary Gland Disorders and Functions
- Thyroid Disorders and Treatments
- Inhalation and Respiratory Drug Delivery
- Hemoglobin structure and function
- Metabolomics and Mass Spectrometry Studies
- RNA regulation and disease
- Genetic factors in colorectal cancer
- Piperaceae Chemical and Biological Studies
- Biomarkers in Disease Mechanisms
- Pediatric health and respiratory diseases
- Cancer Diagnosis and Treatment
- Plant-derived Lignans Synthesis and Bioactivity
- Liver Disease Diagnosis and Treatment
- Pesticide Residue Analysis and Safety
- Apelin-related biomedical research
- Systemic Lupus Erythematosus Research
Chongqing Medical University
2017-2023
Sichuan University
2023
China Medical University
2002-2017
Chinese Academy of Medical Sciences & Peking Union Medical College
2006
Shantou University
2004
Shantou University Medical College
2004
Kagawa University
2000-2002
Third Way
2001
Aim of the Study: To delineate underlying mechanism microRNA-145 modulate balance Th1/Th2 via targeting RUNX3 in asthma patients. Materials and Methods: Peripheral blood samples were collected from patients healthy controls. CD4+ T cells isolated cultured. Using quantitative PCR detect, level mRNA controls, meanwhile, western blot was used to detect protein level. Th1 or Th2 related cytokines measured by enzyme-linked immunosorbent assay. Dual-Luciferase Reporter Assay performed confirm...
It has been suggested that the humoral immune system plays a role in pathogenesis of non-specific interstitial pneumonia (NSIP). Although some circulating autoantibodies to cytoskeletal protein(s) have suggested, antimyofibroblast antibody not investigated patients with idiopathic pulmonary fibrosis (IPF) and NSIP. The purpose this study is evaluate existence sera IPF MRC5 cell line was used as model myofibroblast. anti-MRC5 characterized patient NSIP using Western blotting. Since we found...
Objective: Studies show general agreement that all-trans retinoic acid (atRA) has been linked to the regulation of G protein-coupled receptor (GPCRs) signaling. To further validate effects atRA on cardiovascular GPCRs, present study was designed assess whether will modulate orphan APJ, a homologue angiotensin II type 1 (AT1) receptor.
A novel method for the analysis of components in tobacco flavors was established using stir bar sorptive extraction (SBSE) and thermal desorption coupled with gas chromatography-mass spectrometry (GC-MS). The various parameters affecting analytes from samples to poly (dimethylsiloxane) coated bars conditions were investigated. optimized that sample extracted a (10 mm length 0.5 thickness) at 1100 r/min 60 min ambient temperature. Desorption carried out 20°C ramped 250°C 60°C/min held 2 under...
A novel method for the determination of 5 pyrethroid pesticide residues in tobacco leaf and tea samples was established. The were extracted concentrated with stir bar, desorbed by thermal desorption system, then determined gas chromatography-mass spectrometry (GC-MS). a bar at 1100 r/min 1 h. carried out 300 °C 4 min under helium flow 50 mL/min while maintaining cryofocusing temperature 0 CIS-4 injector GC-MS system. Finally, raised to ⪚C analytes separated GC detected MS. limits detection...
Background . Chronic renal failure (CRF) has become a global health problem and bears huge economic burden. FuShengong Decoction (FSGD) as traditional Chinese medicine multiple pharmacological effects. Objectives To understand the underlying molecular mechanism signaling pathway involved in FSGD treatment of CRF screen differentially expressed proteins rats with treated FSGD. Methods Thirty‐three male Sprague‐Dawley were randomly divided into control group, group. Differentially screened by...
To investigate the renoprotective effects of a Sichuan dark tea-based medicated dietary formula (alternatively referred to as Qing, or clarity in Chinese) on mice with diet-induced obesity (DIO) and explore specific mechanisms involved.
Abstract Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) represents the most common type of CP, characterized by complex pathogenesis and a wide array symptoms, making diagnosis treatment challenging. Acupuncture, widely used for chronic painful conditions, has demonstrated clinical efficacy in restoring prostate function enhancing quality life affected patients. This article critically examines intricate CP/CPPS explores related therapeutic mechanisms acupuncture. Additionally,...