A5016268165- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Apelin-related biomedical research
- Nuclear Receptors and Signaling
- Artificial Intelligence in Healthcare and Education
- Railway Engineering and Dynamics
- Hormonal Regulation and Hypertension
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Structural Engineering and Vibration Analysis
- Renin-Angiotensin System Studies
- Concrete Corrosion and Durability
- Meta-analysis and systematic reviews
- Concrete and Cement Materials Research
- Advanced Measurement and Detection Methods
- Adipose Tissue and Metabolism
- Magnesium Oxide Properties and Applications
- Ion Channels and Receptors
- Aortic aneurysm repair treatments
- Ethics in Clinical Research
- Eicosanoids and Hypertension Pharmacology
- Voice and Speech Disorders
- Machine Learning in Healthcare
- Medical Image Segmentation Techniques
- Microbial Applications in Construction Materials
- Adipokines, Inflammation, and Metabolic Diseases
Capital Medical University
2015-2025
Beijing Friendship Hospital
2023
Zhejiang University
2014
Guilin University of Electronic Technology
2011
Chinese University of Hong Kong
2007
Daping Hospital
2005
Army Medical University
2005
Shantou University
2004
Shantou University Medical College
2004
The apelin receptor APJ is a putative protein related to angiotensin (Ang) type 1 receptor. apelin-APJ system has been implicated in diabetes, but its role the diabetic vasculature and mechanisms involved remain unclear. Our aim here was explore regulatory of aortic vascular tone mice.A Multi Myograph used determine isometric vessel rings from db/db control db/m+ mice. mRNA, phosphorylation, levels APJ, Akt, endothelial nitric oxide synthase (eNOS) were analyzed by reverse...
ABSTRACT Background Hundreds of cancer drugs are approved globally based on surrogate endpoint response rate (RR). However, the characteristics RR‐based approvals remain unknown. Methods In this retrospective study, all drug‐indication pairs RR in United States and China up to December 2023 were analyzed. Results A total 249 RR‐supported identified 98 China. States, (39.4%) indications granted regular approval (RA), whereas China, only 21 (21.4%) followed regulatory pathway, with remainder...
Objective: Studies show general agreement that all-trans retinoic acid (atRA) has been linked to the regulation of G protein-coupled receptor (GPCRs) signaling. To further validate effects atRA on cardiovascular GPCRs, present study was designed assess whether will modulate orphan APJ, a homologue angiotensin II type 1 (AT1) receptor.
Abstract Intracranial stents are becoming increasingly a useful option in the treatment of intracranial aneurysms (IAs). Image simulation releasing stent configuration together with computational fluid dynamics (CFD) prior to intervention will help surgeons optimize scheme. This paper proposed fast virtual stenting IAs based on active contour model (ACM) which was able virtually release within any patient-specific shaped vessel and aneurysm models built real medical image data. In this...
Energy loss (EL) was regarded to be one of the key parameters in predicting rupture risk IA. In this paper, we took varied aspect ratio (AR) as a scaling law create series longitudinal models investigate changes flow pattern and EL AR varies, order explore relationship between characteristic with aneurysm risk. Seven original intracranial aneurysms (IA) similar locations were reconstructed from patient 3D rotational angiography (3DRA) images. Based on these models, different ARs created our...
The hangers of self-anchored suspension bridge need to be tensioned suitably during construction. In view this point, a simplified optimization calculation method cable force for has been developed based on theories, such as minimum bending energy method, and internal balanced influence matrix method. Meanwhile, combined with the weak coherence main adjacently interaction hanger forces, analysis is using MATLAB, which then compared that consider cable's geometric nonlinearity software ANSYS...
<sec> <title>BACKGROUND</title> The surge in artificial intelligence (AI) interventions primary care trials lacks a study on reporting quality. </sec> <title>OBJECTIVE</title> This aimed to systematically evaluate the quality of both published randomized controlled (RCTs) and protocols for RCTs that investigated AI care. <title>METHODS</title> PubMed, Embase, Cochrane Library, MEDLINE, Web Science, CINAHL databases were searched until November 2024. Eligible studies or full exploring was...
Objective: To evaluate the effect of Wendler Glottoplasty to elevate vocal pitch in transgender women. Methods: The voice parameters pre-and 3-month post-surgery 29 women who underwent department otorhinolaryngology head and neck surgery Beijing Friendship Hospital from January, 2017 October, 2020 were retrospectively analyzed. ranged age 19-47 (27.0±6.3) years old. Subjective evaluation was performed using Transsexual Voice Questionnaire for Male Female (TVQMtF). Objective included...
This measurement system uses delaminated principle, measures the three perpendicular direction values of entities. When measured entity is immerged in liquid layer by layer, every layer's image are collected CCD and digitally processed. It introduces basic measuring principle working process measure method. According to Archimedes law, related buoyancy volume that soaked different depth electron balance mathematics models established. Through calculating weight centre gravity computer based...
<p>The principle aim of this paper is to study the crowd-induced vertical dynamic responses complex and flexible footbridges. Stochastic crowd flow real traffic conditions modelled with Monte-Carlo method a numerical integration-based algorithm for structural vibration under excitation developed. Based on footbridge complicated modes, acceleration are obtained, probabilistic characteristics peak being further studied. The calculation results indicate that random response has lognormal...
High fat intake and less physical activity are high risk environmental factors for metabolic syndrome (MS). This study investigated the effects of diet exercise on gene expression profiles associated with nuclear receptors, glucose lipid metabolism, inflammation energy in insulin-sensitive tissues MS rats. rat model was induced by salt, which accorded to our previous work. Wistar rats were divided into normal control (NC), high-fat salt (MS), (NCE) (MSE). The regular means that swim three...
Abnormalities of arteries play a pivotal role in the pathogenesis hypertension. It is unclear what difference vascular structure and function between spontaneous hypertensive rats (SHR) with metabolic syndrome (MS). This study compared arterial SHR MS.