A5044257848- Thyroid Disorders and Treatments
- Adipose Tissue and Metabolism
- Regulation of Appetite and Obesity
- Adipokines, Inflammation, and Metabolic Diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Neonatal Health and Biochemistry
- Sodium Intake and Health
- Biochemical Analysis and Sensing Techniques
- Nutritional Studies and Diet
- Growth Hormone and Insulin-like Growth Factors
- Diet and metabolism studies
- Cardiovascular Health and Risk Factors
- Neuroscience of respiration and sleep
- Blood Pressure and Hypertension Studies
- Stress Responses and Cortisol
- Cardiovascular Disease and Adiposity
- Obesity, Physical Activity, Diet
- Mitochondrial Function and Pathology
- Kawasaki Disease and Coronary Complications
- Pregnancy and preeclampsia studies
- Effects and risks of endocrine disrupting chemicals
- Bariatric Surgery and Outcomes
- Pancreatic function and diabetes
- Lipid metabolism and disorders
- Birth, Development, and Health
Qingdao University
2014-2024
Capital Medical University
2014-2024
China Medical University
2013-2024
Central Hospital of Wuhan
2024
General Hospital of Central Theater Command
2023-2024
Xiamen University
2024
Shandong Provincial QianFoShan Hospital
2024
Beijing Center for Disease Prevention and Control
2020-2024
North China University of Science and Technology
2013-2024
Shandong Center for Disease Control and Prevention
2010-2024
High salt intake is associated with hypertension, which a leading modifiable risk factor for cardiovascular disease.To assess the association of government-led, multisectoral, and population-based intervention reduced blood pressure in Shandong Province, China.This cross-sectional study used data from Shandong-Ministry Health Action on Salt Hypertension (SMASH) program, 5-year to reduce sodium consumption China. Two representative samples adults (aged 18-69 years) were surveyed 2011 (15 350...
Abstract Background The triglyceride-glucose (TyG) index is a reliable surrogate marker of insulin resistance and previous studies have confirmed the association TyG with incident chronic kidney disease (CKD). However, impact longitudinal patterns on CKD risk among non-diabetic population still unknown. Therefore, this study aimed to investigate population. Methods A total 5484 participants who underwent one health examination per year from 2015 2017 were included in prospective study....
Chemerin is a recently discovered metabolic regulator hormone. The pathophysiologic role of this hormone in humans remains unknown. In study, we have compared plasma chemerin levels patients with type 2 diabetes mellitus or without hypertension and control subjects. We also assessed the association body composition parameters these Plasma were found to be markedly increased as normal controls (P < 0.01). Multiple regression analysis showed that waist circumference, diastolic blood pressure,...
Nesfatin-1 is an anorexigenic peptide involved in energy homeostasis. Recently, nesfatin-1 was reported to decrease blood glucose level and improve insulin sensitivity high-fat diet-fed rats. However, little information known about the influence of on lipid metabolism either physiological or diabetic condition. This study undertook whether pathophysiology Streptozotocin-induced type 2 mice (T2DM), which induced by a combination high-calorie diet two low-doses Streptozotocin. We observed that...
Folic acid (FA) supplementation is associated with a lower risk of the neural tube and heart defects recommended for women childbearing age. Although there are detailed recommendations, differences in initiation time duration FA remain poorly studied.
Chronic stress may facilitate the development of metabolic diseases. Insulin resistance is present long before clinical manifestations individual abnormalities. To explore whether chronic an independent risk factor insulin resistance, we investigated relationship between system, selected parameters energy homeostasis, and in a Chinese population.We recruited 766 workers employed at four companies Beijing. The degree was determined using homeostasis model assessment (HOMA-IR). highest...
In China, population-based blood pressure levels and prevalence of hypertension are increasing. Meanwhile, sodium intake, a major risk factor for hypertension, is high. 2011, to develop intervention priorities salt reduction control project in Shandong Province (population 96 million), cross-sectional survey was conducted collect information on intake prevalence, awareness, treatment, control.Complex, multistage sampling methods were used select provincial-representative adult sample. Blood...
Suboptimal health status (SHS) has become a new public challenge in China. This study investigated whether high SHS is associated with psychosocial stress, changes cortisol level and/or glucocorticoid receptor (GR) isoform expression. Three-hundred eighty-six workers employed three companies Beijing were recruited. The score was derived from data collection the questionnaire (SHSQ-25). short standard version of Copenhagen Psychosocial Questionnaire (COPSOQ) used to assess job-related stress....
Advances in the immunology have identified that interleukin (IL)‑17 and IL‑35 are cytokines with diverse functions, serving important roles autoimmune diseases chronic inflammation. Checkpoint inhibitor pneumonitis (CIP) is focal or diffuse lung inflammation induced by immune checkpoint inhibitors underlying pathogenesis has not been fully explored. The aim of present study was to investigate IL‑17A IL‑35, correlation between their levels different T cell subsets CIP. peripheral blood...
How to provide advanced respiratory support for coronavirus disease (COVID-19) maximize population-level survival while optimizing mechanical ventilator access is unknown.
Abstract Browning of white adipose tissue (WAT) is become an appealing target for therapeutics in the treatment obesity and related metabolic diseases. Dapagliflozin widely used type 2 diabetes, it also found that drug exhibits regulate systemic metabolism such as obesity, insulin resistance hepatic steatosis. However, precise role dapagliflozin on WAT remodeling remains to be elucidated. The current study aimed explore browning high-fat diet (HFD)-induced obese mice. Male C57BL/6J mice ( n...
This study compares the effect of nanosized silicon dioxide (nanosized SiO 2 ) and microsized (microsized particles on fibrogenesis in rats. Wistar rats were instilled intratracheally with saline, 20 mg or , sacrificed at 1 months after instillation. The lungs analysed for changes lung/body coefficient hydroxyproline content. Changes pathology fibrotic grade observed by use hematoxylin eosin Van Gieson dyeing. expression interleukin-4 (IL-4) transforming growth factor-b1 (TGF-b1) was...
There are an increasing number of patients suffering from fatty liver caused by type 2 diabetes. We intended to study the preventive and therapeutic effect L-carnitine (LC) on nonalcoholic disease (NAFLD) in streptozotocin (STZ)-induced diabetic mice explore its possible mechanism.Thirty male Kungming were randomly divided into five groups: control group, pre-treatment group (125 mg/kg BW), low-dose BW) high-dose (250 group. The morphology hepatocytes was observed light electron microscopy....
Effective treatment of osteomyelitis remains a formidable clinical challenge. The rapid emergence multidrug-resistant bacteria has renewed interest in developing antimicrobial biomaterials using antiseptic silver ions to treat osteomyelitis. However, inadequate local retention and severe cytotoxic effects have limited the use ionic for bone grafts. We recently developed novel porous nano-hydroxyapatite/polyamide 66 (nHP66)-based nanoscaffold materials containing varied concentrations (Ag+)...