Hua Liu

ORCID: 0000-0003-3325-3824
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About
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Research Areas
  • Hepatitis B Virus Studies
  • Ophthalmology and Visual Impairment Studies
  • Adipokines, Inflammation, and Metabolic Diseases
  • biodegradable polymer synthesis and properties
  • Adipose Tissue and Metabolism
  • Acute Ischemic Stroke Management
  • Retinal Diseases and Treatments
  • Electrospun Nanofibers in Biomedical Applications
  • Polymer Surface Interaction Studies
  • Bone Tissue Engineering Materials
  • Bone fractures and treatments
  • Hepatitis C virus research
  • Orthopaedic implants and arthroplasty
  • Respiratory viral infections research
  • Liver Disease Diagnosis and Treatment
  • Visual perception and processing mechanisms
  • Corneal surgery and disorders
  • Immune cells in cancer
  • Retinal Development and Disorders
  • Congenital Heart Disease Studies
  • Cervical Cancer and HPV Research
  • Nuclear Engineering Thermal-Hydraulics
  • Risk and Safety Analysis
  • Retinal Imaging and Analysis
  • Metabolomics and Mass Spectrometry Studies

Dalian Medical University
2023-2025

Jinzhou Medical University
2021-2025

Anyang Eye Hospital
2025

Shandong Center for Disease Control and Prevention
2025

Aerospace Center Hospital
2025

Peking University
2025

Cangzhou Central Hospital
2024

First Affiliated Hospital of Xinjiang Medical University
2024

Daping Hospital
2020-2024

Army Medical University
2020-2024

Chemerin is a recently discovered metabolic regulator hormone. The pathophysiologic role of this hormone in humans remains unknown. In study, we have compared plasma chemerin levels patients with type 2 diabetes mellitus or without hypertension and control subjects. We also assessed the association body composition parameters these Plasma were found to be markedly increased as normal controls (P < 0.01). Multiple regression analysis showed that waist circumference, diastolic blood pressure,...

10.2310/jim.0b013e3181ec5db2 article EN Journal of Investigative Medicine 2010-10-01

Abstract Background Cervical cancer is the fourth most common in women. Up to 99% of cervical cases are associated with high-risk human papillomavirus (HPV). Sexual behavior a direct risk factor for HPV infection, and sexually active college students, therefore, receive attention vaccination. At present, Chinese studies lack in-depth research on influencing factors, limited cancer, HPV, or vaccine, without comprehensive consideration. This study investigated students’ prevention treatment...

10.1186/s12889-022-14718-0 article EN cc-by BMC Public Health 2022-12-05

Purpose: To investigate the effect of Ca2+/calmodulin-dependent protein kinase II (CAMKII) δ subtypes (CAMK2D) on sodium iodate (NaIO3)-induced retinal degeneration in mice. Methods: Bioinformatics analysis and Western blot experiments were used to screen significantly differentially expressed genes age-related macular (AMD) disease. CAMK2D knockdown overexpression models constructed by lentivirus (LV) infection adult pigment epithelial cell line-19 (ARPE-19) cells vitro. Flow cytometry was...

10.1167/iovs.66.1.63 article EN cc-by-nc-nd Investigative Ophthalmology & Visual Science 2025-01-28

Objective: More attention should be paid to glucose metabolism in children with Williams-Beuren syndrome (WBS). Methods: The clinical data of a child diagnosed WBS due diabetic ketoacidosis (DKA) were retrospectively analyzed, and the related literature was reviewed. Results: An 8-year-old boy presented thickened upper lip, low palatal arch, strong heart sound, rumbling murmur apex area, little pigmentation webbed margin fingers toes, atypical elfin features. Blood gas analysis showed severe...

10.62617/mcb1336 article EN Molecular & cellular biomechanics 2025-02-19

Background: To explore the sex-specific risk factors of associated with arterial stiffness. Methods: A total 28,291 participants from Kailuan study cohort were enrolled in this study. multivariate linear regression analysis and a logistic model used to analyze influencing arteriosclerosis (indexed using brachial–ankle pulse wave velocity, baPWV) between different sexes. Results: The incidence (baPWV greater than or equal 1400 cm/s) was 54.70%. males (62.13%) higher females (37.41%) (p &lt;...

10.31083/rcm25478 article EN cc-by Reviews in Cardiovascular Medicine 2025-02-20

Osteogenesis is tightly complemented with angiogenesis during the bone regeneration process. In this study, to synergistically enhance osteogenesis and of poly(l-lactide) (PLLA), PLLA/chitosan (PLLA/CS) composite fibrous membrane was prepared first by combining electrospinning thermally induced phase separation technologies. Then, aid polydopamine (PDA) coating, two types bioactive molecules icariin (ICA) deferoxamine (DFO) were chosen singly or simultaneously surface modify as-prepared...

10.1021/acsabm.8b00129 article EN ACS Applied Bio Materials 2018-07-16

Abstract Objective to identify multimorbidity patterns among middle-aged and older adults in China examine how these are associated with incident disability recovery of independence. Methods data were from The Health Retirement Longitudinal Study. We included 14,613 persons aged ≥45 years. Latent class analysis (LCA) was conducted clinical meaningfulness. Multinomial logistic models used determine the adjusted association between Results we identified four patterns: ‘low morbidity’ (67.91%...

10.1093/ageing/afac177 article EN Age and Ageing 2022-08-01

The objective of the present investigation was to explore possible effect 5-HT3 receptor antagonist tropisetron on expression levels inflammatory factors interleukin 6 (IL-6), creatine kinase isoenzyme (CK-MB), soluble growth stimulating gene 2 protein (sST2) and immunoglobulin E (IgE), as well cardiac action potential in septic rats.The cecal ligation perforation (CLP) method utilized construct abdominal infarction rats. A total 68 male adult Sprague Dawley rats were used, including 40 for...

10.1016/j.biopha.2018.11.142 article EN Biomedicine & Pharmacotherapy 2018-12-04

A method to mediate biomineralization of electrospinning poly(L-lactide) (PLLA) fibrous membrane assisted by polydopamine (PDA) coating was developed obtain enhanced osteoconductive activity. The mechanism, surface composition, morphology and hydrophilicity the original modified PLLA membranes were characterized. Results revealed that PDA effectively accelerated formation hydroxyapatite (HA) on resulted a great increase in hydrophilicity. Moreover, tensile property while almost kept...

10.1088/1748-605x/ab2f2d article EN Biomedical Materials 2019-07-04

CD11c+ macrophages/dendritic cells (MDCs) are increased and display the classically activated M1-like phenotype in obese adipose tissue (AT) may contribute to AT inflammation insulin resistance. Stat1 is a key transcription factor for MDC polarization into phenotype. Here, we examined role of obesity-induced resistance using mice with specific knockout MDCs (cKO). was upregulated phosphorylated, indicating activation, early persistently wild-type fed high-fat diet (HFD). Compared littermate...

10.2337/db20-0634 article EN Diabetes 2020-12-15

Purpose: This study aims to investigate the relationship between Sodium Glucose Co-transporter-2 inhibitors (SGLT2i) treatment and fibrosis in patients with Metabolic dysfunction-associated steatotic liver disease (MASLD) combined Type 2 Diabetes Mellitus (T2DM) Major Adverse Cardiovascular Cerebrovascular Events (MACCEs). Methods: A case–control was conducted, involving 280 MASLD T2DM treated at First Affiliated Hospital of Xinjiang Medical University from January 2014 October 2023. Among...

10.2147/ijgm.s460200 article EN cc-by-nc International Journal of General Medicine 2024-06-01

To investigate refractive development and prevalence of myopia in children aged 3-6 years Hebei Province, China, to explore the developmental law refraction, so as clinically guide prediction intervention myopia.In May 2019, a total 6120 people were inspected 68 kindergartens 11 cities Province. Child refraction was checked under noncycloplegia using handheld binocular vision screener (SW-800, SUOER, Tianjin, China). Axial length (AL) corneal radius curvature (CR) measured an ocular biometry...

10.1155/2021/3656831 article EN Computational and Mathematical Methods in Medicine 2021-12-16
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