A5072564923- Lipid metabolism and disorders
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Management and Research
- Veterinary Pharmacology and Anesthesia
- Liver Disease Diagnosis and Treatment
- Diabetes Treatment and Management
- Metabolism, Diabetes, and Cancer
- Anesthesia and Sedative Agents
- Cardiovascular Health and Disease Prevention
- Thyroid Cancer Diagnosis and Treatment
- Diabetes and associated disorders
- Peroxisome Proliferator-Activated Receptors
- Cancer-related molecular mechanisms research
- Diet, Metabolism, and Disease
- Pancreatic function and diabetes
- Anesthesia and Pain Management
- Diabetes Management and Education
- Advanced Measurement and Detection Methods
- Pharmacological Effects and Assays
- Metabolism and Genetic Disorders
- Infrared Target Detection Methodologies
- Blood Pressure and Hypertension Studies
- Diet and metabolism studies
- Cancer, Hypoxia, and Metabolism
- Veterinary Equine Medical Research
First Affiliated Hospital of Xinjiang Medical University
2012-2025
Xinjiang Medical University
2012-2025
Xinjiang Uygur Autonomous Region Disease Prevention and Control Center
2024-2025
China Pharmaceutical University
2024
Zhejiang A & F University
2018-2022
China International Science and Technology Cooperation
2022
China National Nuclear Corporation
2022
Chengdu Medical College
2022
Changzhi Medical College Peace Hospital
2018
China Academy of Information and Communications Technology
2016
Primary thyroid lymphoma (PTL) is an extremely rare form of malignancy, merely accounting for 2-5% all cases. Owing to its low incidence and the absence concrete clinical manifestations, PTL frequently misdiagnosed as thyroiditis or cancer, thereby presenting a significant hurdle accurate diagnosis. This case study centered around 46-year-old female patient. We meticulously detailed diagnosis treatment process her primary mucosa-associated lymphoid tissue (MALT) marginal zone lymphoma....
Abstract Type 2 diabetes mellitus (T2DM) with hypertension (DH) is the most common diabetic comorbidity. Patients DH have significantly higher rates of cardiovascular disease morbidity and mortality. The objective this study was to develop validate a nomogram model for prediction an individual's risk developing DH. A total 706 T2DM patients who met criteria were selected divided into training set (n = 521) validation 185) according discharge time patients. By using multivariate logistic...
The harm of nonalcoholic fatty liver disease to human health is increasing, which calls for urgent prevention and treatment the disease. Isoorientin an effective ingredient Chinese herbal medicine with anti-inflammatory antioxidant effects. However, effect isoorientin in still unclear. In this study, combined vivo vitro experiments, through pathological observation, flow cytometry, immunofluorescence western blot analysis explore role steatosis reveal its molecular mechanism. results...
This study aims to investigate the molecular mechanism of Adenovirus type 36 (Ad36) in adipocyte differentiation and glucolipid metabolism.Rat obesity model was established by Ad36 infection high-fat diet, respectively. Comparison body weight, clinical biochemical indicators, insulin sensitivity lipid heterotopic deposition between these two models performed. Ad36-induced vitro also established. The binding rate FoxO1, PPARγ its target gene promoter detected using ChIP. mRNA protein...
Abstract Background The prevalence of diabetes and obesity has been continuously rising worldwide over the last three decades, particularly in China. varies widely among different ethnicities. In this study, we investigated obesity, as well associated factors for Kazakh adults Xinjiang to improve screening. Methods We collected data from physical examination 2018, including a total sample 118,505 Altay District. Data on demographic characteristics, medical history, examination, fasting...
To develop a nomogram model that predicts the risk of diabetic nephropathy (DN) incidence in type 2 diabetes mellitus (T2DM) patients.
Purpose: This study aims to investigate the relationship between Sodium Glucose Co-transporter-2 inhibitors (SGLT2i) treatment and fibrosis in patients with Metabolic dysfunction-associated steatotic liver disease (MASLD) combined Type 2 Diabetes Mellitus (T2DM) Major Adverse Cardiovascular Cerebrovascular Events (MACCEs). Methods: A case–control was conducted, involving 280 MASLD T2DM treated at First Affiliated Hospital of Xinjiang Medical University from January 2014 October 2023. Among...
Objectives To investigate the expression levels of aromatase cytochrome P450 enzyme (P450AROM) and related molecules—estrogen receptor-beta (ER-β), Ki-67, p53—in prolactinoma tumor tissue from pre- post-menopausal women, to determine associations invasiveness with these genes. Methods This study recruited 90 patients who underwent adenoidectomy between 2012 2017. Information was collected regarding clinical characteristics, hormones, laboratory tests, magnetic resonance imaging-assessed...
Objective To analyze the clinical characteristics and controllable risk factors of osteoporosis in elderly men with type‐2 diabetes mellitus (T2DM). Methods A total 250 OP patients T2DM were included present study. Patients one or more common chronic diseases (including hypertension, coronary heart disease, failure, bronchitis, nephrosis, cirrhosis), a course than 3 years defined as complicated diseases. Blood glucose, cholesterol, triglyceride, low‐density lipoprotein, high‐density calcium,...
Patients with type 2 diabetes respond differently to sitagliptin, an oral anti-hyperglycemic medication. whose blood sugar levels were effectively managed while using sitagliptin had significantly lower of a protein called suppressor cytokine signaling 3 (SOCS3), according our earlier research. In this study, we established in vitro insulin resistance cell model for human HepG2 cells investigate the possible mechanism effect on glucose metabolism via SOCS3/phosphoinositide 3-kinase...
The purpose of this study was to investigate the effects dietary Selenohomolanthionine (SeHLan) on antioxidant status and immune response in canine parvovirus (CPV) vaccinated puppies. In study, 30 weaned puppies were randomly divided into six groups: control group (-Se/-Vacc), immunization (-Se/+Vacc), supplementation sodium selenite (SS/+Vacc, 0.35 mg/kg DM), low-dose SeHLan (SeHLan-L/+Vacc, mid-dose (SeHLan-M/+Vacc, 1.0 high-dose (SeHLan-H/+Vacc, 2.0 DM). fed for 42 days with Vanguard...
AIM: The objective of this study was to investigate the effects a combination emulsified isoflurane, lidocaine, and fentanyl (EI-L-F) compared with efficacy isoflurane alone (EI), lidocaine (EI-L) or (EI-F) for anaesthetising dogs.METHODS: Eight mongrel dogs were anesthetised EI (8 mL/kg/hour), EI-L (3 mg/kg/hour 6 mL/kg/hour isoflurane), EI-F (1.5 μg/kg/hour EI-L-F (5 1 2.4 lidocaine). Each dog received all four treatments there 15-day washout period between treatments. dogs' anaesthesia...
Our paper is a study about metabolism syndrome (MS) incidence situations of different nationalities, including Uighur, Kazak and Han nationality in Xinjiang by means cross-sectional survey compare differences adaptabilities applications the diagnostic criteria for MS recommended Adult Treatment Protocol III National Cholesterol Education Program America (ATP III), International Diabetes Federation (IDF) Chinese Society (CDS) three groups populations. Conclusion tell us, Uighur population...
Radiation-induced esophageal injury (RIEI) is a major dose-limiting complication of radiotherapy, especially for and thoracic cancers. RIEI multi-factorial multi-step process, which regulated by complex network DNA, RNA, protein metabolite. However, it unclear metabolites are altered ionizing radiation how these changes affect progression. In this work, we established rat model with 0–40 Gy X-ray irradiation. Esophageal irradiation using ≥25 induced significant to rats, such as body weight,...
Oxidative stress in the body occurs when production of free radicals overwhelms antioxidant defence systems. The aim this study was to examine effects a tiletamine/zolazepam-xylazine-tramadol combination on status, lipoperoxidase and blood cell indicators eight miniature pigs. Baseline measures were recorded prior anaesthesia, then animals anaesthetized with tiletamine/zolazepam (3.5 mg/kg), xylazine (1.32 tramadol (1.8 mg/kg). Blood samples collected from anterior vena cava at 15, 30, 60,...
Abstract Cats were injected with 2.4 mg/kg of tiletamine-zolazepam, 0.36 xylazine, and 0.8 tramadol, then blood was collected from their peripheral veins at 0.5, 1, 4, 8, 24, 48, 72, 168 h after the injection. Before injection, same cats used as control group (0 h). Biochemical haematological parameters measured. The results revealed that combination compounds produced good immobilisation, minimal changes over time in biochemical parameters, which within biologically acceptable limits.