A5011065352- Animal Virus Infections Studies
- Virus-based gene therapy research
- Viral gastroenteritis research and epidemiology
- Viral Infections and Immunology Research
- Selenium in Biological Systems
- Moringa oleifera research and applications
- Immunotherapy and Immune Responses
- Lipid metabolism and biosynthesis
- Microbial infections and disease research
- Endoplasmic Reticulum Stress and Disease
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Impact on Reproduction
- Cancer-related Molecular Pathways
- RNA modifications and cancer
- Heavy Metal Exposure and Toxicity
- Ferroptosis and cancer prognosis
- Liver Disease Diagnosis and Treatment
- Rabbits: Nutrition, Reproduction, Health
- Peroxisome Proliferator-Activated Receptors
- Influenza Virus Research Studies
- Arsenic contamination and mitigation
Zhejiang A & F University
2012-2025
China International Science and Technology Cooperation
2022
Shanghai Veterinary Research Institute
2012
Abstract Of the three branches of unfolded protein response (UPR) that were reportedly activated by porcine epidemic diarrhea virus (PEDV), PERK is recently shown to act as an upstream regulator oxidative cells. However, it remains unknown if and how activation during PEDV infection would result in stress, whether its downstream molecules affect replication. Here, we demonstrate with strain YJH/2015 triggered UPR Vero E6 cells activating PERK/eIF2α pathway led significant increase expression...
The harm of nonalcoholic fatty liver disease to human health is increasing, which calls for urgent prevention and treatment the disease. Isoorientin an effective ingredient Chinese herbal medicine with anti-inflammatory antioxidant effects. However, effect isoorientin in still unclear. In this study, combined vivo vitro experiments, through pathological observation, flow cytometry, immunofluorescence western blot analysis explore role steatosis reveal its molecular mechanism. results...
The purpose of this study was to investigate the effects dietary Selenohomolanthionine (SeHLan) on antioxidant status and immune response in canine parvovirus (CPV) vaccinated puppies. In study, 30 weaned puppies were randomly divided into six groups: control group (-Se/-Vacc), immunization (-Se/+Vacc), supplementation sodium selenite (SS/+Vacc, 0.35 mg/kg DM), low-dose SeHLan (SeHLan-L/+Vacc, mid-dose (SeHLan-M/+Vacc, 1.0 high-dose (SeHLan-H/+Vacc, 2.0 DM). fed for 42 days with Vanguard...
We developed a multiplex ligation-dependent probe amplification (MLPA) assay for the simultaneous detection of 6 clinically relevant viral pathogens causing porcine reproductive failure, that is and respiratory syndrome virus (PRRSV), Japanese encephalitis (JEV), classical swine fever (CSFV), circovirus type 2 (PCV2), pseudorabies (PRV) parvovirus (PPV). The limits varied among target organisms from 1 to 8 copies per MLPA assay. was evaluated with 346 heparinized umbilical cord blood...
Abstract Background Porcine reproductive and respiratory syndrome virus (PRRSV) is a highly prevalent endemic swine pathogen that can cause significant economic losses to the global industry. Host-targeted antiviral drugs have been developed as new strategy for therapy. In this regard, selenium nanoparticles (SeNPs) attracted increasing attention in biomedical field, given their effects. The purpose of study was investigate whether chitosan-coated SeNPs (CS-SeNPs) could affect PRRSV...