A5021030437- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
- Virus-based gene therapy research
- SARS-CoV-2 and COVID-19 Research
- Viral Infections and Immunology Research
- Selenium in Biological Systems
- Chromatography in Natural Products
- Bioactive natural compounds
- Phytochemicals and Antioxidant Activities
- Biochemical and Molecular Research
- Biological and pharmacological studies of plants
- Polymer crystallization and properties
- Virology and Viral Diseases
- Bacillus and Francisella bacterial research
- Plant Virus Research Studies
- biodegradable polymer synthesis and properties
- Plant Stress Responses and Tolerance
- Moringa oleifera research and applications
- Food Quality and Safety Studies
- T-cell and Retrovirus Studies
- Nematode management and characterization studies
- Natural Fiber Reinforced Composites
- Endoplasmic Reticulum Stress and Disease
- Antibiotic Resistance in Bacteria
- Agriculture, Soil, Plant Science
Wuhan Polytechnic University
2024
Zhejiang A & F University
2019-2024
Qingdao University
2022
Shenyang University of Chemical Technology
2020
Huazhong Agricultural University
2015-2019
Jilin University
2018
Porcine reproductive and respiratory syndrome virus (PRRSV) is a highly prevalent endemic swine pathogen that causes significant economic losses to the global industry. Selenium nanoparticles (SeNPs) have attracted increasing attention in biomedical field, given their antiviral effects. This study aimed investigate inhibitory effect of chitosan-coated SeNPs (CS-SeNPs) on PRRSV replication.In this study, CS-SeNPs were synthesized by chemical reduction characterized assessing morphology, size...
Maleic anhydride (MAH) grafting to different polyolefins with similar degree can have effects on crystallization, crystal structure, and mechanical thermal properties. The leads a smaller size, less ordered lamellar shorter long period for HDPE, LLDPE, PP. makes PP packing the most almost no effect LLDPE. does not that much impact crystallization ability of HDPE/PP blend, but appreciably reduces crystalline PP-g-MAH, due dramatical drop in its molecular weight during process. As result, very...
Porcine epidemic diarrhea virus (PEDV) is an enteric pathogen in the swine industry, causing high mortality neonatal piglets. Efficient PEDV infection usually relies on presence of trypsin, yet mechanism trypsin dependency ambiguous. Here, we identified two strains, trypsin-enhanced YN200 and trypsin-independent DR13, which spike (S) protein exhibits a stronger ability to induce syncytium formation cleaved by than that DR13. Using full-length infectious cDNA clone, confirmed S determinant...
Abstract Of the three branches of unfolded protein response (UPR) that were reportedly activated by porcine epidemic diarrhea virus (PEDV), PERK is recently shown to act as an upstream regulator oxidative cells. However, it remains unknown if and how activation during PEDV infection would result in stress, whether its downstream molecules affect replication. Here, we demonstrate with strain YJH/2015 triggered UPR Vero E6 cells activating PERK/eIF2α pathway led significant increase expression...
This study investigated the impact of variety and harvest time on visual appearance, nutritional quality, functional active substances six lotus root cultivars: "Xinsanwu", "Wuzhi No. 2", "Baiyuzhan", "Huaqilian", "Elian 6", 5". Samples were collected monthly from December 2023 to April 2024. A nutrient analysis revealed a decrease in water content with delayed harvest. The total soluble solids sugar peaked towards end middle-to-late periods, respectively. Starch levels initially increased...
Both porcine epidemic diarrhoea virus (PEDV) and transmissible gastroenteritis (TGEV), which cause high mortality in piglets produce similar clinical symptoms histopathological morphology, belong to the genus Alphacoronavirus. Serological diagnosis plays an important role distinguishing pathogen species. Together with spike (S) protein, nucleocapsid (N) protein is one of immunodominant regions among coronaviruses. In this study, two-way antigenic cross-reactivity between N proteins PEDV TGEV...
Abstract Mycobacterium tuberculosis (Mtb) remains a leading cause of morbidity and mortality worldwide, as two billion people are latently infected with Mtb . To address drug resistance the limitations current vaccines, characteristics candidate vaccines need to be explored. Here, we report three-dimensional structure Rv0315 at 1.70 Å resolution, novel immunostimulatory antigen demonstrate that is an inactive β-1,3-glucanase glycoside hydrolase 16 (GH16) family. Our study further elaborates...
The purpose of this study was to investigate the effects dietary Selenohomolanthionine (SeHLan) on antioxidant status and immune response in canine parvovirus (CPV) vaccinated puppies. In study, 30 weaned puppies were randomly divided into six groups: control group (-Se/-Vacc), immunization (-Se/+Vacc), supplementation sodium selenite (SS/+Vacc, 0.35 mg/kg DM), low-dose SeHLan (SeHLan-L/+Vacc, mid-dose (SeHLan-M/+Vacc, 1.0 high-dose (SeHLan-H/+Vacc, 2.0 DM). fed for 42 days with Vanguard...
We developed a multiplex ligation-dependent probe amplification (MLPA) assay for the simultaneous detection of 6 clinically relevant viral pathogens causing porcine reproductive failure, that is and respiratory syndrome virus (PRRSV), Japanese encephalitis (JEV), classical swine fever (CSFV), circovirus type 2 (PCV2), pseudorabies (PRV) parvovirus (PPV). The limits varied among target organisms from 1 to 8 copies per MLPA assay. was evaluated with 346 heparinized umbilical cord blood...
In this study, "Honghu White Lotus", "Red Lotus (HH)", "Hunan Cunshan (CS)", "Wuyi Xuanlian", "Space 36", "Fujian Jianning (JB)", "Jiangsu Yangzhou (JY)", and "Suzhou Dongshan Lotus" were selected as experimental subjects. The lotus seed flesh plumule of each cultivar for nutritional quality functional active substance analyses. Comparing different cultivars seeds, the protein crude fat contents JY highest at 65.59 mg/g 13%, respectively. VC content JB is 41.56 204.29 mg/g, has lowest...
Pine wilt disease is a devastating of pine trees caused by wood nematode (PWN), Bursaphelenchus xylophilus (Steiner & Buhrer) Nickle. We studied the bacteria carried B. from Fushan Mountain and Qingdao University Campus (F Q samples) pathogenicity two PWN samples to explore relationship between companion its pathogenicity. Based on metagenomic analysis, distribution was signifi cantly different. At phylum level, Proteobacteria largest in samples, 85 65% F respectively. family...
Porcine reproductive and respiratory syndrome virus (PRRSV) is a significant pathogen causing substantial financial losses in the global swine industry. The prevention of PRRSV hampered due to frequent gene recombination among different strains PRRSV. In this study, new strain, PRRSV-HQ-2020, was identified from nursery piglets Yunnan Province, China, 2020. complete genome analysis revealed that PRRSV-HQ-2020 highly similar JXA1-like (lineage 8.7 PRRSV, isolated China 2008) 5′UTR, nsp1–9,...
Abstract Background Porcine reproductive and respiratory syndrome virus (PRRSV) is a highly prevalent endemic swine pathogen that can cause significant economic losses to the global industry. Host-targeted antiviral drugs have been developed as new strategy for therapy. In this regard, selenium nanoparticles (SeNPs) attracted increasing attention in biomedical field, given their effects. The purpose of study was investigate whether chitosan-coated SeNPs (CS-SeNPs) could affect PRRSV...