A5100638881- Sleep and Wakefulness Research
- Lung Cancer Research Studies
- Alcohol Consumption and Health Effects
- Neuroendocrine Tumor Research Advances
- Cancer Treatment and Pharmacology
- Circadian rhythm and melatonin
- Liver Disease Diagnosis and Treatment
- Cancer, Hypoxia, and Metabolism
- Pancreatic and Hepatic Oncology Research
- Sleep and related disorders
- Dementia and Cognitive Impairment Research
- Cardiovascular Syncope and Autonomic Disorders
- Renal cell carcinoma treatment
- Cancer-related gene regulation
- Ethics in Business and Education
- Psychology of Moral and Emotional Judgment
- Neurological Disorders and Treatments
- Wheat and Barley Genetics and Pathology
- Ginseng Biological Effects and Applications
- Clostridium difficile and Clostridium perfringens research
- Attention Deficit Hyperactivity Disorder
- Helicobacter pylori-related gastroenterology studies
- Migraine and Headache Studies
- Gout, Hyperuricemia, Uric Acid
- Genetics and Plant Breeding
Fuzhou University
2017-2024
Nanchang University
2014-2024
Sun Yat-sen University Cancer Center
2024
The Seventh Affiliated Hospital of Sun Yat-sen University
2024
Sun Yat-sen University
2024
State Key Laboratory of Oncology in South China
2024
First Affiliated Hospital of Xinxiang Medical University
2024
Xinxiang Medical University
2020-2024
Jining Medical University
2019-2024
Luohe Medical College
2019
Schizophrenia (SCH) is a complex neurodevelopmental disorder, whose pathogenesis not fully elucidated. This article aims to reveal disease-specific brain structural and functional changes their potential genetic basis by analyzing the characteristics of magnetic resonance imaging (MRI) in SCH patients related gene expression patterns. Differentially expressed genes (DEGs) between healthy control (NC) groups GSE48072 dataset were identified functionally analyzed, protein-protein interaction...
The present study investigated the effect of dilemma type, framing, and number saved lives on moral decision making. A total 591 undergraduates, with a mean age 20.56 (SD = 1.37) were randomly assigned to 12 groups basis grid two types (the trolley problem or footbridge dilemma) by three frames (positive, neutral, negative frame) different numbers workers (5 15 people). main effects frame, all significant. interaction type independent factors Results indicated that judgment is affected...
Introduction Recently, some epidemiological studies have reported that cognitive disorders in elderly people is accelerated with traumatic brain injury. But the causal relationship between injury and AD still an area of controversy. Aims Our review was conducted to estimate relation risk AD. Methods All longitudinal population-based comparing incidence subjects without from their inception September 2020 were searched The Cochrane Library, PubMed, Medline, Embase, Web Science restriction...
Abstract Background To develop and compare machine learning models based on triphasic contrast-enhanced CT (CECT) for distinguishing between benign malignant renal tumors. Materials Methods In total, 427 patients were enrolled from two medical centers: Center 1 (serving as the training set) 2 external validation set). First, 1781 radiomic features individually extracted corticomedullary phase (CP), nephrographic (NP), excretory (EP) CECT images, after which 10 selected by minimum redundancy...
To evaluate the prognostic significance of lymph node metastasis, extent examined nodes (ELNs) and ratio (LNR) for resected pancreatic neuroendocrine neoplasms (pNENs).Surgically pNENs were assimilated from Surveillance, Epidemiology, End Results database. Kaplan-Meier Cox proportional hazard models used to examine effect clinicopathological characteristics on overall survival; Harrell's concordance index was performed assess accuracy all independent factors; Spearman's rank correlation...
We aim to examine the predictive effect of total number examined lymph nodes on N stage and survival in pancreatic neuroendocrine neoplasms (pNENs) determine optimal threshold.A pNENs data set from 2004 2013 was extracted Surveillance, Epidemiology, End Result database. Multivariate logistic regression Cox proportional hazards model were used identify factors associated with survival, respectively.Totally, 1280 analyzed. The 11 15 showed a strong association N1 (6-10 vs 11-15: odds ratio,...
Objective: To describe the epidemiological characteristics of hand, foot and mouth disease (HFMD) in Nanchang city during 2008–2012 to detect potential temporal-spatial clusters. Methods: Data on HFMD City were derived from National Notifiable Infectious Disease Reporting System (NNIDRS). We used descriptive methods HFMD. Space-time scan statistic, based Space-Time Permutation model, was adopted determine presence space-time interaction clusters Nanchang. Results: There 29 062 cases reported...
Simvastatin (SIM), a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, has been reported to inhibit the activity of hepatitis B virus (HBV), however, mechanism underlying its antiviral function remains unknown. Minichromosome maintenance (MCM) 7, component MCM complex, act as an important host factor aiding genome replication in cells. The present study demonstrated that downregulation MCM7 inhibited expression proteins transferred by adenoviral vectors. This suggests association...
Background: A proportion of patients with intermediate-stage hepatocellular carcinoma (HCC) can achieve cancer free status (CFS) during treatment. However, the prognostic value CFS throughout course dynamic surveillance and treatment hasn’t been fully understood.Materials Methods: This longitudinal cohort study examined data from electronic medical record system four hospitals in China between January 1, 2007 to May 31, 2019. The Sun Yat-sen University Cancer Center served as derivation...
Objective: To investigate the effects of osimertinib on proliferation, migration and invasion procollagen-lysine 2-oxoglutarate 5-dioxygenase 2 (PLOD2) overexpressing HCC827 cells explore potential mechanism PLOD2 induced resistance. Methods: We transfected with LV-vector LV-over/PLOD2. The expression was detected by quantitative real time polymerase chain reaction (qRT-PCR) western blotting. proliferation HCC827-vector HCC827-PLOD2 were evaluated 3-(4, 5-dimethyl-2-thiazolyl)-2,...