- Gastric Cancer Management and Outcomes
- PI3K/AKT/mTOR signaling in cancer
- Colorectal Cancer Screening and Detection
- Retinal Development and Disorders
- MicroRNA in disease regulation
- Esophageal Cancer Research and Treatment
- Pancreatic and Hepatic Oncology Research
- Liver Disease Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Parvovirus B19 Infection Studies
- Multiple Myeloma Research and Treatments
- Platelet Disorders and Treatments
- Peptidase Inhibition and Analysis
- Neurological disorders and treatments
- Ureteral procedures and complications
- Opioid Use Disorder Treatment
- Esophageal and GI Pathology
- Diet and metabolism studies
- Viral-associated cancers and disorders
- Eosinophilic Disorders and Syndromes
- Galectins and Cancer Biology
- Acute Myeloid Leukemia Research
- Glycosylation and Glycoproteins Research
- Chronic Myeloid Leukemia Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
Jinzhou Medical University
2023-2025
Shaoxing Second Hospital
2013-2025
Shaoxing University
2024-2025
Henan Provincial Eye Hospital
2025
Henan Provincial People's Hospital
2025
Zhengzhou University
2025
Dalian Medical University
2023-2025
Cangzhou Central Hospital
2018-2022
Purpose: To investigate the effect of Ca2+/calmodulin-dependent protein kinase II (CAMKII) δ subtypes (CAMK2D) on sodium iodate (NaIO3)-induced retinal degeneration in mice. Methods: Bioinformatics analysis and Western blot experiments were used to screen significantly differentially expressed genes age-related macular (AMD) disease. CAMK2D knockdown overexpression models constructed by lentivirus (LV) infection adult pigment epithelial cell line-19 (ARPE-19) cells vitro. Flow cytometry was...
Purpose The tetraspanin CD151 acts as a promoter of metastasis and invasion in several tumors. However, the role human gastric cancer (HGC) remains unclear. Methods Twenty HGC specimens matched nontumor samples, epithelial cells (HGEC), four cell lines were used to analyze expression. Short hairpin RNA-mediated downregulation expression was performed examine proliferation metastasis/invasion vivo vitro. relationship with integrin α3 investigated by silencing followed co-immunoprecipitation...
Purpose: Carfilzomib has been approved for use in relapsed and refractory multiple myeloma (RRMM). Cardiac toxicities have reported with the of carfilzomib. We aimed to determine overall incidence risk cardiac RRMM patients treated carfilzomib using a meta-analysis. Methods: searched several databases relevant articles. Prospective trials evaluating adequate data on were included analysis. Pooled incidence, Peto ORs, 95% CIs calculated according heterogeneity selected studies. Results: A...
Department of Gastrointestinal and Minimally Invasive Surgery Shaoxing Second Hospital Shaoxing, Zhejiang, China [email protected]
Objective To investigate the serum soluble urokinase-type plasminogen activator (suPAR)in patients with multiple myeloma,its relationship 2-year survival rate and its clinical significance in predicting disease prognosis.Methods Enzyme-linked immunosorbent assay was applied to determine levels of suPAR 40 initial diagnosed MM 30 healthy persons as control group.The were divided into three groups:effective (13 cases),remission (19 cases) invalid (8 cases).Results Usually there expression...
Objective The aim of the study was to explore difference between expression CDg7 in peripheral blood and bone marrow on acute myeloid leukemia (AML n=30). Methods A flow cytometric quantitative analysis levels for CD87 performed fresh blast cells from patients with leukaemia using CD87, monoclonal antibodies. Analysis matched t -test. Results values 14 M5 cases are 9.47 %~80.32 %, 11.49 %~87.46 % blood. 8 M4 14.27 %~46.28 %,and 14.79 %~47.19 6 M2 4.67 %~34.26 8.96 %~39.78 CDs, 2 MI 3.56...
To investigate the clinical significance and safety of interferon in treatment chronic myeloproliferative tumors (MPN).In this prospective study, a total 120 patients with advanced MPN admitted to our hospital between April 2016 August 2020 were assessed for eligibility recruited, including 62 JAK2V617F mutation-positive ET (ET group) 58 PV (PV group). assigned (1 : 1) receive interferon-α (IFN-α) or hydroxyurea (HU). A similar subgrouping method IFN-α HU was introduced PV. Outcome measures...