A5052998609- Peptidase Inhibition and Analysis
- RNA modifications and cancer
- Bioactive Compounds in Plants
- Machine Learning in Bioinformatics
- Cancer Immunotherapy and Biomarkers
- Bioinformatics and Genomic Networks
- MicroRNA in disease regulation
- Oral microbiology and periodontitis research
- Advanced biosensing and bioanalysis techniques
- RNA Interference and Gene Delivery
- Cancer-related molecular mechanisms research
- Protease and Inhibitor Mechanisms
- Cell Adhesion Molecules Research
- Cytokine Signaling Pathways and Interactions
Jinan Stomatological Hospital
2015-2021
Background: Oral cancer is one of the most frequent solid cancers worldwide, and oral squamous cell carcinoma (OSCC) constitutes approximately 90% cancers. The discovery reliable prognostic indicators would be a potential strategy for OSCC treatment. In present study, we aim to explore underlying mechanism by which microRNA-145 (miR-145) affected OSCC. Methods: Forty-eight patients diagnosed with were enrolled obtain tissues adjacent normal tissues. targeting relationship between miR-145...
The advance of new treatment strategies for more effective management oral cancer requires identification novel biological targets. Therefore, the purpose this study is to identify biomarkers associated with tumorigenesis and prognostic signature by comparing gene expression profile squamous cell carcinomas (OSCCs).Four datasets including GSE25099, GSE30784, GSE37991, GSE41613 were collected from Gene Expression Omnibus (GEO) database. Ontology (GO) Kyoto Encyclopedia Genes Genomes (KEGG)...