- Algal biology and biofuel production
- Spaceflight effects on biology
- Advanced Nanomaterials in Catalysis
- Nanoparticles: synthesis and applications
- Aquatic Ecosystems and Phytoplankton Dynamics
- Aquaculture Nutrition and Growth
- Planetary Science and Exploration
- Nanomaterials for catalytic reactions
- Photosynthetic Processes and Mechanisms
- TiO2 Photocatalysis and Solar Cells
- Microbial Metabolic Engineering and Bioproduction
- Marine and coastal ecosystems
- Bee Products Chemical Analysis
- Nanoplatforms for cancer theranostics
- Ruminant Nutrition and Digestive Physiology
- Laser-Ablation Synthesis of Nanoparticles
- Vibrio bacteria research studies
- Saffron Plant Research Studies
- Medicinal Plants and Neuroprotection
- Eicosanoids and Hypertension Pharmacology
- Essential Oils and Antimicrobial Activity
- Space Science and Extraterrestrial Life
- Dye analysis and toxicity
- Phytochemistry and Bioactivity Studies
- Reproductive Physiology in Livestock
University of Cagliari
2019-2025
Nowadays, fungal infections increase, and the demand of novel antifungal agents is constantly rising. In present study, silver, titanium dioxide, cobalt (II) hydroxide (II,III) oxide nanomaterials have been synthesized from Spirulina platensis extract. The synthesis mechanism has studied using GCMS FTIR thus confirming involvement secondary metabolites, mainly amines. obtained products analysed XRD, SEM, TGA zeta potential techniques. findings revealed average crystallite size 15.22 nm with...
Synthesis of silver nanoparticles (Ag NPs) using microalgae is gaining recognition for its environmentally friendly and cost-effective nature while maintaining high activity NPs. In the present study, Ag NPs were synthesized a methanolic extract Chlorella vulgaris subjected to calcination. The X-ray diffraction (XRD) analysis showed crystalline products with
The development of efficient photocatalysts is crucial in addressing water pollution concerns, specifically the removal organic dyes from wastewater. In this context, use silver nanoparticles (Ag NPs) might represent a method to achieve high dye degradation efficiencies. On other hand, classical Ag NP production process involves several reactants and operating conditions, which make it poorly sustainable. present work, NPs were synthesized according new sustainable involving natural extracts...
The cultivation of cyanobacteria by exploiting available in situ resources represents a possible way to supply food and oxygen astronauts during long-term crewed missions on Mars. Here, we evaluated the possibility cultivating extremophile cyanobacterium Chroococcidiopsis thermalis CCALA 050 under operating conditions that should occur within dome hosting recently patented process produce nutrients medium adopted cultivate this cyanobacterium, named Martian medium, was obtained using mixture...
The production of food or nutraceutical compounds using in-situ available resources is one the most relevant challenges in view realization crewed mission to Mars. possibility grow Haematococcus pluvialis CCALA 1081 a medium obtained from Mars regolith and astronauts' urine simulants under an atmosphere CO2 mimicking Martian after pressurization, investigated this work. experimental results showed that H. could be grown only such thus theoretically reducing zero payload related fertilizers...
holds promise for biotechnological applications due to its rapid growth and ability produce valuable bioactive compounds like phycocyanin (PC). This study explores the impact of salinity brewery wastewater (BWW) on mixotrophic cultivation
The green synthesis of silver (Ag) and zinc oxide (ZnO) nanoparticles (NPs), as well Ag/Ag2O/ZnO nanocomposites (NCs), using polar apolar extracts Chlorella vulgaris, offers a sustainable method for producing nanomaterials with tunable properties. impact the environment nanomaterials’ characteristics on cytotoxicity was evaluated by examining reactive species production their effects mitochondrial bioenergetic functions. Cytotoxicity assays PC12 cells, cell line originated from rat...
The rising global focus on healthy lifestyles and environmental sustainability has prompted interest in repurposing plant-based by-products for health benefits. With increasing life expectancy, the incidence of neurodegenerative diseases—characterized by complex, multifactorial mechanisms such as abnormal protein aggregation, mitochondrial dysfunction, oxidative stress, inflammation—continues to grow. Medicinal plants, with their diverse bioactive compounds, offer promising therapeutic...
This study explores the mixotrophic cultivation of Limnospira platensis using dairy byproducts, specifically scotta whey (SW), buttermilk wastewater (BMW), and (DWW), to promote biomass production enhance composition bioactive compounds. By assessing various concentrations (1%, 2%, 4% v v−1) these byproducts in a modified growth medium, this aims evaluate their effect on L. growth, phycocyanin (C-PC) content, fatty acid methyl ester (FAME) profiles. The results show that optimal was achieved...
Inflammatory response represents one of the main mechanisms healing and tissue function restoration. On other hand, chronic inflammation leads to excessive secretion pro-inflammatory cytokines involved in onset several diseases. Oxidative stress condition may contribute worsening inflammatory state fall, increasing reactive oxygen species (ROS) production release. Polyphenols can counteract oxidative stress, modulating release toxic molecules interacting with physiological defenses, such as...
Potato is a staple food crop and an important source of dietary energy. Its tubers contain several essential amino acids, vitamins, minerals phytochemicals that contribute to the nutritional value this product. Recently, scientific interest has focused on purple red potatoes that, due presence anthocyanins, may be considered as natural powerful functional food. The aim study was evaluate characteristics pigmented varieties, types anthocyanins accumulated level both beneficial (vitamin C...
Cyanobacteria largely contribute to the biogeochemical carbon cycle fixing ~ 25% of inorganic on Earth. However, acquisition and assimilation mechanisms in are still underexplored regardless being great importance for shedding light origins autotropism Earth providing new bioengineering tools crop yield improvement. Here, we fully characterized these from polyextremophile cyanobacterium Chroococcidiopsis thermalis KOMAREK 1964/111 comparison with model cyanobacterial strain, Synechococcus...
Abstract In the present work, possibility to grow strain Synechococcus nidulans CCALA 188 on Mars using a medium mimicking one obtainable in situ available resources, i.e. so-called Martian medium, under an atmosphere by pressurization of CO 2 , is investigated. The goal obtain biomass with high-value products sustain crewed mission Mars. results show that replacement 40% vol Z-medium same volume does not affect cultivation and leads slight improvement productivity. Under consisting pure...
Microalgae are considered as a potential source of bioactive compounds to be used in different fields including food and pharmaceutical industry. In this context, fatty acid esters hydroxy-fatty acids (FAHFA) emerging new class with anti-inflammatory anti-diabetic properties. An existing gap the field algal research is limited knowledge regarding production these compounds. Our questions aimed determine whether microalga H. pluvialis can synthesize FAHFA levels increased when cultivated...
Long-term spatial missions will require sustainable methods for biomass production using locally available resources. This study investigates the feasibility of cultivating Chlorella vulgaris, a high value microalgal specie, leachate Martian regolith and synthetic human urine as nutrient sources. The microalga was grown in standard medium (BBM) mixed with 0, 20, 40, 60, or 100% (MM). MM did not significantly affect final concentrations. Total carbohydrate protein contents decreased...
Abstract With an unsupervised GC–MS metabolomics approach, polar metabolite changes of the microalgae Coccomyxa melkonianii SCCA 048 grown under standard conditions for seven weeks were studied. C. was sampled at Rio Irvi River, in mining site Montevecchio-Ingurtosu (Sardinia, Italy), which is severely contaminated by heavy metals and shows high concentrations sulfates. The partial-least-square (PLS) analysis data indicated that growth characterized increase levels threonic acid, myo...
The growth of microalgae as food for astronauts is one the main challenges in view future manned missions on Mars. possibility cultivating cyanobacterium Synechococcus nidulans a medium consisting mixture simulated regolith leachate and astronauts’ urine, called Martian Medium, investigated with aim reducing payload deriving from nutrients to bring Earth. strain was capable surviving grow biomass productivity about 29 g m−3 day−1 containing 40% v/v Medium urine. composition strain, showing...
This study explores the mixotrophic cultivation of Arthrospira platensis using dairy byproducts, specifically scotta whey (SW), buttermilk wastewater (BMW), and (DWW), to promote biomass production enhance composition bioactive compounds. By assessing various concentrations (1%, 2%, 4% v v-1) these byproducts in a modified growth medium, research aims evaluate their effect on A. growth, phycocyanin (C-PC) content, fatty acid methyl ester (FAME) profiles. The results show that optimal was...