A5032456643- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Sex work and related issues
- Adolescent Sexual and Reproductive Health
- Cervical Cancer and HPV Research
- HIV Research and Treatment
- Hepatitis B Virus Studies
- HIV/AIDS Impact and Responses
- Reproductive tract infections research
- Genital Health and Disease
- COVID-19 epidemiological studies
- Vaccine Coverage and Hesitancy
- Herpesvirus Infections and Treatments
- Syphilis Diagnosis and Treatment
- HIV/AIDS drug development and treatment
- Mathematical and Theoretical Epidemiology and Ecology Models
- HIV-related health complications and treatments
- Female Genital Mutilation/Cutting Issues
- Animal Disease Management and Epidemiology
- Global Cancer Incidence and Screening
- Hepatitis C virus research
- Sexuality, Behavior, and Technology
- Poverty, Education, and Child Welfare
- COVID-19 and Mental Health
- Homelessness and Social Issues
Imperial College London
2015-2024
Medical Research Council
2019-2024
Université Laval
2013-2023
University of Miami
2022
Parker University
2022
University of Mississippi Medical Center
2022
Medical University of Graz
2022
Centre hospitalier de l'Université Laval
2022
London Centre for Neglected Tropical Disease Research
2019-2021
The London College
2020
The WHO Director-General has issued a call for action to eliminate cervical cancer as public health problem. To help inform global efforts, we modelled potential human papillomavirus (HPV) vaccination and screening scenarios in low-income lower-middle-income countries (LMICs) examine the feasibility timing of elimination at different thresholds, estimate number cases averted on path elimination.The Cervical Cancer Elimination Modelling Consortium (CCEMC), which consists three independent...
New WHO guidelines recommend ART initiation for HIV-positive persons with CD4 cell counts ≤500 cells/µL, a higher threshold than was previously recommended. Country decision makers must consider whether to further expand eligibility accordingly.We used multiple independent mathematical models in four settings-South Africa, Zambia, India, and Vietnam-to evaluate the potential health impact, costs, cost-effectiveness of different adult criteria under scenarios current expanded treatment...
Background and objective: HIV chemoprophylaxis may be a future prevention strategy to help control the global epidemic of HIV/AIDS. Safety efficacy trials two agents are currently underway. We assess expected number cases prevented cost-effectiveness hypothetical program among men who have sex with in large US city. Design methods: developed stochastic compartmental mathematical model using HIV/AIDS surveillance data simulate impact 5-year under varying assumptions for epidemiological,...
Bivalent and quadrivalent human papillomavirus (HPV) vaccines are now licensed in several countries. Furthermore, clinical trials examining the efficacy of a nonavalent vaccine underway. We aimed to compare potential population-level effectiveness bivalent, quadrivalent, candidate HPV vaccines. developed an individual-based, transmission-dynamic model infection disease population stratified by age, gender, sexual activity, screening behavior. The was calibrated highly behavior, epidemiology,...
A 2017 systematic review and meta-analysis of 55 prospective studies found the adjusted risk HIV acquisition to be at least tripled in individuals with herpes simplex virus type 2 (HSV-2) infection. We aimed assess potential contribution HSV-2 infection incidence, given an effect on acquisition.
Objective: Increased male participation in antenatal care and uptake of couple voluntary counselling testing (VCT) for HIV could reduce horizontal vertical transmission sub-Saharan Africa. Methods: Randomized controlled trial to compare pregnant women's acceptance written invitations VCT pregnancy information sessions (PISs) – the control group their sexual partners (MSPs) among these Khayelitsha, South Results: All women study accepted invitation letters agreed invite attend or PIS as...
Our aim was to examine the potential incremental impact of vaccinating boys against human papillomavirus (HPV) on vaccine-type infection in females and males, using an individual-based HPV transmission-dynamic model. Under base assumptions (vaccine efficacy = 99%, duration protection 20 years, coverage 70%), 12-year-old boys, addition girls, resulted reduction HPV-16/18 (HPV-6/11) incidence over 70 years 16% (3%) 23% (4%) males. The benefit decreased with improved vaccination girls. Given...
During the COVID-19 pandemic, men who have sex with (MSM) in USA reported similar or fewer sexual partners and reduced HIV testing care access compared before pandemic. Pre-exposure prophylaxis (PrEP) use has also declined. We aimed to quantify potential effect of on incidence HIV-related mortality among US MSM.