- Moyamoya disease diagnosis and treatment
- Blood Coagulation and Thrombosis Mechanisms
- Venous Thromboembolism Diagnosis and Management
- Heparin-Induced Thrombocytopenia and Thrombosis
- Parasitic infections in humans and animals
- Mitochondrial Function and Pathology
- Neurological Complications and Syndromes
- RNA regulation and disease
- RNA and protein synthesis mechanisms
- Infectious Encephalopathies and Encephalitis
- Alcoholism and Thiamine Deficiency
- Teratomas and Epidermoid Cysts
- Bacillus and Francisella bacterial research
- Herpesvirus Infections and Treatments
- Cerebral Venous Sinus Thrombosis
- Fetal and Pediatric Neurological Disorders
- Neonatal and fetal brain pathology
- Connective tissue disorders research
- Pediatric Urology and Nephrology Studies
- Cardiovascular Issues in Pregnancy
- Cytomegalovirus and herpesvirus research
- Genetic and Kidney Cyst Diseases
- Platelet Disorders and Treatments
- High Altitude and Hypoxia
- Parvovirus B19 Infection Studies
Imperial College Healthcare NHS Trust
2018-2022
Charing Cross Hospital
2019-2021
National Health Service
2018
St George’s University Hospitals NHS Foundation Trust
2017
Leicester Royal Infirmary
2012
<h3>BACKGROUND AND PURPOSE:</h3> <i>Arg179His</i> mutations in <i>ACTA2</i> are associated with a distinctive neurovascular phenotype characterized by straight course of intracranial arteries, absent basal Moyamoya collaterals, dilation the proximal internal carotid and occlusive disease terminal arteries. We now add to neuroimaging features these patients describing their unique constellation brain malformative findings that could flag diagnosis cases which targeted cerebrovascular imaging...
Vaccine‐induced immune thrombotic thrombocytopenia (VITT) is a rare prothrombotic syndrome associated with an adenoviral vector‐based vaccine ChAdOx1 CoV‐19 (AstraZeneca, University of Oxford) or Ad26.COV2.S (Janssen; Johnson & Johnson). VITT characterized by thrombosis, often at unusual sites, particularly cerebral venous sinus thrombosis (CVST) thrombocytopenia, low fibrinogen, and significantly raised D‐dimer level.1.Scully M. Singh D. Lown R. et al.Pathologic antibodies to platelet...