A5079682804- Fermentation and Sensory Analysis
- Horticultural and Viticultural Research
- Effects and risks of endocrine disrupting chemicals
- Toxic Organic Pollutants Impact
- Biochemical and biochemical processes
- Agricultural and Food Production Studies
- Historical and socio-economic studies of Spain and related regions
- Carcinogens and Genotoxicity Assessment
- Health, Environment, Cognitive Aging
- Microbial Metabolites in Food Biotechnology
- Botanical Research and Applications
- Atmospheric chemistry and aerosols
- Wine Industry and Tourism
- Microbial Metabolism and Applications
- Analytical chemistry methods development
- Probiotics and Fermented Foods
- Vitamin C and Antioxidants Research
- Antioxidant Activity and Oxidative Stress
- Monoclonal and Polyclonal Antibodies Research
- Pharmaceutical and Antibiotic Environmental Impacts
- Identification and Quantification in Food
- Insect and Pesticide Research
- Antimicrobial Resistance in Staphylococcus
- Per- and polyfluoroalkyl substances research
- Glycosylation and Glycoproteins Research
New York State Department of Health
2018-2024
Corning (United States)
2024
Wadsworth Center
2018-2024
Universidad de La Rioja
2008-2024
Center for Biomedical Research of La Rioja
2022-2024
Hospital Del Mar
2023
Centro de Investigación Biomédica en Red de Salud Mental
2023
Universitat Autònoma de Barcelona
2023
University at Albany, State University of New York
2018-2022
New York University
2021
Organophosphate esters (OPEs) are widely used as flame retardants and plasticizers in consumer products, which contributes to widespread exposure of humans. OPE diester metabolites urine have been biomarkers human these chemicals. Little is known, however, about occurrence temporal variability urinary concentrations In this study, 11 were measured 213 samples collected from 19 volunteers Albany, New York, United States, at 3-day intervals for five weeks investigate concentrations. Diphenyl...
Human exposure to neonicotinoid insecticides (hereafter "neonics") is a concern. Spot urine samples have been widely used in the assessment of neonics. Urinary concentrations, however, can vary greatly over time due variable exposure, potentially leading misclassification. In this study, within- and between-individual variability urinary concentrations 13 neonics their metabolites collected consecutively for up 44 days from 19 individuals were examined. We also measured seven oxidative...
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants. Urinary concentrations of mono-hydroxylated metabolites PAHs (OH-PAHs) have been used as biomarkers these chemicals' exposure in humans. Little is known, however, with regard to intra- and inter-individual variability OH-PAH their association oxidative stress. We conducted a longitudinal study measurement urinary 15 OH-PAHs 7 stress (OSBs) DNA damage [8-hydroxy-2′-deoxyguanosine (8-OHdG)], lipid [malondialdehyde...
Exposure to phthalates may affect fetal growth, but previous studies are inconsistent and have not explored the trimester-specific effects of on repeated measures growth. To assess associations maternal phthalate metabolites urine concentrations with growth birth outcomes identify potential windows vulnerability exposure. Population-based prospective cohort study, Generation R Study (2002–2006). Data analysis was performed from November 2019 June 2020. Rotterdam, Netherlands. 1379 pregnant...
Oxidative stress in humans is affected by the health and nutritional status as well exposure to external environmental factors. To evaluate effects of factors, an assessment baseline levels diurnal variations oxidative healthy individuals needed. In this study, we examined intra- inter-individual variability biomarkers (OSBs) lipids (malondialdehyde [MDA] four F2-isoprostane isomers, namely, 8-isoprostaglandinF2α [8-PGF2α], 11β-prostaglandinF2α [11-PGF2α], 15(R)-prostaglandinF2α [15-PGF2α],...
Human exposure to phthalates is ubiquitous and has received considerable attention due their association with adverse health outcomes, including type 2 diabetes mellitus (T2DM). Nevertheless, earlier studies that link phthalate T2DM yielded ambiguous results. Furthermore, associate oxidative stress then are scant. In this diabetic case-control study, urine samples collected from 101 individuals aged 28-68 years Jeddah, Saudi Arabia, were analyzed determine 20 metabolites (PhMs) seven...
Abstract Background Exposure to bisphenols may affect fetal growth and development. The trimester-specific effects of on repeated measures remain unknown. Our objective was assess the associations maternal bisphenol urine concentrations with birth outcomes identify potential critical exposure periods. Methods In a population-based prospective cohort study among 1379 pregnant women, we measured A, S F in first, second third trimester. Fetal head circumference, length weight were trimester by...
Antimicrobial resistance is recognized as one of the principal threats to public health worldwide, yet problem increasing. Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) strains are among most difficult treat in clinical settings due MRSA nearly all available antibiotics. The cyclic anionic lipopeptide antibiotic daptomycin (DAP) mainstay anti-MRSA therapy. decreased susceptibility DAP (DAP [DAPr]) reported frequently accompanied a paradoxical decrease β-lactam...
Exposure of humans to pesticides is widespread. Measurement urinary levels and their metabolites often used in the assessment body burdens exposure doses these chemicals. An understanding temporal variability within individuals critical for accurate assessment. We examined within- between-individual concentrations nine organophosphate pyrethroid insecticides as well two phenoxy herbicides urine collected consecutively up 44 days from 19 individuals. Seven oxidative stress biomarkers also...
The determination of oxidative stress biomarkers (OSBs) is useful for the assessment health status and progress diseases in humans. Whereas previous methods OSBs urine were focused on a single marker, this study, we present method simultaneous damage to lipids, proteins, DNA. 2,4-Dinitrophenylhydrazine (DNPH) derivatization followed by solid phase extraction (SPE) high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) allowed 8-hydroxy-2′-deoxyguanosine (8-OHdG),...
Fetal exposure to phthalates and bisphenols may lead vascular developmental adaptations, which program later cardiovascular disease. We examined the associations of fetal with childhood blood pressure.In a population-based, prospective cohort study among 1,064 mother-child pairs, we measured maternal urine phthalate bisphenol concentrations in first, second third trimester pregnancy. pressure at mean age 9.7 years (standard deviation 0.2 years) old. Analyses were performed for total group,...
Exposure to bisphenols and phthalates might influence bone health. We hypothesized that exposure during fetal life has persistent effects on development. To analyze the associations of with health in school-aged children. Among 1,362 mother-child pairs participating a population-based cohort study, we measured maternal urinary concentrations at first, second third trimester high performance liquid chromatography electrospray ionization-tandem mass spectrometry. Total body mineral density...
Fetal exposure to endocrine disruptors such as phthalates and bisphenols may lead developmental metabolic adaptations. We examined associations of maternal phthalate bisphenol urine concentrations during pregnancy with lipids, insulin, glucose at school age. In a population-based, prospective cohort study among 757 mother–child pairs, we measured in first, second third trimester pregnancy. non-fasting insulin blood their children mean age 9.7 (standard deviation 0.2) years. Analyses were...
Objective The purpose of this study was to investigate the associations urinary phthalates and bisphenols at age 6 years old with body fat cardiovascular risk factors 10 change from years. Methods Among 471 Dutch children, concentrations BMI, mass index, android mass, blood pressure, glucose, insulin, lipids were measured. Results An interquartile range increase in di‐ n ‐octyl phthalate (DNOP) metabolites associated an increased overweight (odds ratio: 1.44; 95% CI: 1.11‐1.87, 1.43;...
Abstract A new method for determining endocrine disrupter compounds (EDCs) in sewage sludge is described this paper. EDCs studied were bisphenol (BPA) and alkylphenols (APs). In order to obtain a fast simple method, selective pressurised liquid extraction (SPLE) focused ultrasound solid–liquid (FUSLE) tested. Best results SPLE obtained using Florisil as clean‐up sorbent dichloromethane solvent, while temperature was the only significant variable. Analyte by completed one cycle of 1 min at...
Altered systemic oxidative stress is a consequence of environmental exposures and diseases, among other factors. The extent in humans assessed through the analysis biomarkers (OSBs) biospecimens such as urine. Allantoin an OSB, specific product oxidation uric acid, that measurable In this study, concentrations inter- intraindividual variability urinary allantoin were determined healthy individuals. results compared with those found for OSBs lipids, proteins, DNA same set samples. was all...