A5082669585- Physical Activity and Health
- Obesity, Physical Activity, Diet
- Gestational Diabetes Research and Management
- Pharmaceutical Quality and Counterfeiting
- Pharmaceutical Economics and Policy
- Cardiac Health and Mental Health
- Intellectual Property and Patents
- Cardiac, Anesthesia and Surgical Outcomes
- Behavioral Health and Interventions
- Frailty in Older Adults
- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Pleistocene-Era Hominins and Archaeology
- Suicide and Self-Harm Studies
- Global Public Health Policies and Epidemiology
- Cardiovascular and exercise physiology
- Morphological variations and asymmetry
- Animal Behavior and Reproduction
- Law, Economics, and Judicial Systems
- Primate Behavior and Ecology
- Cardiac and Coronary Surgery Techniques
- Healthcare Systems and Reforms
- Cardiac Structural Anomalies and Repair
- European and International Contract Law
- Urban Transport and Accessibility
Durham University
2015-2025
Seattle Pacific University
2013
Importance The safety and effectiveness of mitral valve repair via thoracoscopically-guided minithoracotomy (minithoracotomy) compared with median sternotomy (sternotomy) in patients degenerative regurgitation is uncertain. Objective To compare the vs a randomized trial. Design, Setting, Participants A pragmatic, multicenter, superiority, clinical trial 10 tertiary care institutions UK. were adults undergoing surgery. Interventions 1:1 concealed allocation to receive either or performed by...
Summary The feasibility, safety and efficacy of prehabilitation in adult patients awaiting elective cardiac surgery are unknown. A total 180 participants undergoing were allocated randomly to receive either standard pre‐operative care or prehabilitation, consisting exercise inspiratory muscle training. primary outcome was change six‐minute walk test distance from baseline assessment. Secondary outcomes included strength (maximal pressure); sarcopenia (handgrip strength); quality life...
Objectives: Human biologists are increasingly interested in measuring and comparing physical activities different societies. Sedentary behavior, which refers to time spent sitting or lying down while awake, is a large component of daily 24 hours movement patterns humans has been linked poor health outcomes such as risk all-cause cardiovascular mortality, independently activity. As such, it important for researchers, with the aim human patterns, most effectively use resources available them...
Substandard and falsified (SF) medical products are a serious health economic concern that disproportionately impact low- middle-income countries marginalized groups. Public education campaigns demand-side interventions may reduce risk of SF exposure, but the effectiveness such campaigns, their likelihood benefitting everybody, is unclear. Nationwide pilot communication involving multiple media, were deployed in Ghana, Nigeria, Sierra Leone, Uganda 2020-2021. Focus group discussions (n=73...
Abstract Background Autism Adapted Safety Plans (AASP) have been proposed to help prevent self-harm and suicidality among autistic adults. The introduction of such plans not only needs be clinically effective but also cost-effective. aim this work was establish how the cost-effectiveness AASP could assessed. Specifically, whether tools techniques used collect data for health economic evaluation intervention are feasible acceptable people. Methods A feasibility external pilot randomised...
Research has shown that individuals have an optimal walking speed-a speed which minimizes energy expenditure for a given distance. Because the varies with mass and lower limb length, it also sex, males in any population tending to faster speeds. This potentially creates energetic dilemma mixed-sex groups. Here we examine choices made by of varying stature, mass, sex together. Individuals (N = 22) walked around track alone, significant other (with without holding hands), friends same opposite...
Sedentary time is associated with increased risk of type 2 diabetes, but the association between objectively measured sedentary and incident gestational diabetes mellitus (GDM) has not been tested. The purpose this paper to test associations self-reported television during pregnancy GDM plasma glucose levels among women at high for GDM. At 20 weeks' gestation, pregnant (n = 188) in North East England a factor wore an activPAL accelerometer reported their usual time. Participants underwent...
Introduction Prehabilitation prior to surgery has been shown reduce postoperative complications, length of hospital stay and improve quality life after cancer limb reconstruction surgery. However, there are minimal data on the impact prehabilitation in patients undergoing cardiac surgery, despite fact these generally older have more comorbidities frailty. This trial will assess feasibility a intervention consisting exercise inspiratory muscle training preoperative functional capacity adult...
BACKGROUND & AIMS:Postcolonoscopy Q10 colorectal cancer incidence and mortality rates are higher for endoscopists with low polyp detection rates.Using the UK's National Endoscopy Database (NED), which automatically captures real-time data, we assessed if providing feedback of case-mix-adjusted mean number polyps (aMNP), as a key performance indicator, improved endoscopists' performance.Feedback was delivered via theory-informed, evidence-based audit intervention. METHODS:This multicenter,...
Abstract Substandard and falsified (SF) medical products pose a major threat to public health socioeconomic development, particularly in low- middle-income countries. In response, education campaigns have been developed alert consumers about the risks of SF medicines provide guidance on ‘safer’ practices, along with other demand- supply-side measures. However, little is currently known potential effectiveness such while structural constraints accessing quality-assured persist. This paper...
Autistic people are a high-risk group for self-harm and suicide. There no evidence-based suicide prevention interventions developed specifically autistic people. We undertook pilot feasibility randomised controlled trial of autism adapted safety plans (AASP) to reduce
Human footprint fossils have provided essential evidence about the evolution of human bipedalism as well social dynamics makers, including estimates speed, sex and group composition. Generally such are made by comparing with modern controls; however, previous studies not accounted for variation in dimensions coming from load bearing activities. It is likely that a portion hominins who created these fossil footprints were carrying significant load, offspring or foraging loads, which caused...
Approaches to understanding why physical activity (PA) tends decline during pregnancy are generally based on individualized behavioral models, examining "barriers" or "enablers." In contrast, we used a social practice approach explore the ways in which women negotiate PA within contexts and routines of their everyday lives. Semistructured interviews were conducted with 18 pregnant who had been classed as being at risk gestational diabetes. We found that leisure-time activities valued...
Television (TV) time is associated with poor cardiometabolic health outcomes. This finding commonly attributed to duration of sitting or patterns high TV time, but there very little evidence on this link.
<h3>Introduction:</h3> Reporting is an essential component of efforts to combat the distribution and circulation substandard falsified (SF) medical products worldwide. However, little known about why health care professionals (HCPs) do not report suspect national medicine regulatory authority (NMRA) what measures might address this. This pilot study aimed assess utility a smartphone application for reporting SF in Tanzania Indonesia. <h3>Methods:</h3> At baseline, 2017, HCPs completed survey...
<h3>Introduction</h3> Post-colonoscopy colorectal cancer incidence and mortality rates are higher for endoscopists with low polyp detection rates. Using the UK's National Endoscopy Database (NED), which automatically captures data real-time, we assessed if providing feedback of case-mix-adjusted Mean Number Polyps (aMNP), a key performance indicator (KPI), in theory-informed evidence-based behaviour change intervention improved endoscopists' performance. <h3>Methods</h3> The multicentre,...
Abstract Little is known about the relationship between socioeconomic position (SEP) and duration patterning of objectively measured sedentary time (ST) among adults, especially adults at high risk diabetes. The aim this study was to examine cross-sectional associations SEP with ST (total, prolonged ST, breaks in ST) self-reported TV pregnant women gestational diabetes UK. At 20 weeks’ gestation, ( n =174) wore an activPAL accelerometer reported their usual time. Generalized linear mixed...