Mirko Salomón Alva-Sánchez

ORCID: 0000-0003-3936-3629
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About
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Research Areas
  • Advanced Radiotherapy Techniques
  • Radiation Therapy and Dosimetry
  • Radiation Dose and Imaging
  • Radiation Effects and Dosimetry
  • Laser-induced spectroscopy and plasma
  • Advanced X-ray and CT Imaging
  • Medical Imaging Techniques and Applications
  • Digital Radiography and Breast Imaging
  • Radiation Detection and Scintillator Technologies
  • Photoacoustic and Ultrasonic Imaging
  • Laser-Matter Interactions and Applications
  • Laser Design and Applications
  • Nanoplatforms for cancer theranostics
  • Photodynamic Therapy Research Studies
  • Particle Detector Development and Performance
  • Advanced Materials Characterization Techniques
  • Laser-Plasma Interactions and Diagnostics
  • Radiopharmaceutical Chemistry and Applications
  • Advances in Oncology and Radiotherapy
  • Nuclear Physics and Applications
  • Chemical Reactions and Isotopes
  • Breast Cancer Treatment Studies
  • Particle accelerators and beam dynamics
  • Health Systems, Economic Evaluations, Quality of Life
  • Boron Compounds in Chemistry

Universidade Federal de Ciências da Saúde de Porto Alegre
2018-2025

University of Health Sciences
2021-2025

University of Health Sciences Antigua
2021-2025

Universidade Federal do Rio Grande do Sul
2019-2021

Universidade de São Paulo
2009-2013

Hospital de Câncer de Barretos
2012

Universidade de Ribeirão Preto
2012

Universidade Brasil
2010

While laser wakefield acceleration (LWFA) in the bubble regime demands ultra-short, high-peak-power pulses, operation self-modulated (SM-LWFA) works with more relaxed pulse conditions, albeit at cost of lower beam quality. Modern systems can deliver few-terawatt pulses tens femtoseconds kilohertz repetition rates. These are well-suited for developing SM-LWFA applications where high average energy and charge prioritized over Such beams could be used to generate high-energy bremsstrahlung...

10.1063/5.0244268 article EN cc-by Physics of Plasmas 2025-03-01

The diagnostic medical practice using X-rays significantly contributes to the collective dose worldwide, where inherent risk in each examination is proportional absorbed dose, which related deterministic and stochastic effects of ionizing radiation. Therefore, due necessity optimizing radiological procedure, this study aimed reduce patients undergoing X-ray examinations by evaluating parameter that modifies spectral distribution. Birch Marshall method was employed reconstruct modify spectra...

10.15446/mo.n69.115340 article EN cc-by-nd MOMENTO 2024-07-30

OBJETIVO: Determinar, por simulação Monte Carlo, os espectros de feixes cobaltoterapia em profundidade na água e fatores correção para doses absorvidas dosímetros termoluminescentes fluoreto lítio. MATERIAIS E MÉTODOS: As simulações dos secundários da fonte clínica cobalto-60 foram realizadas com o código Carlo PENELOPE, diversas profundidades água. Medidas experimentais dose profunda obtidas câmara ionização condições referência radioterapia. Os obtidos através razão entre as absorções...

10.1590/s0100-39842010000200013 article PT Radiologia Brasileira 2010-04-01

While laser wakefield acceleration (LWFA) in the bubble regime demands ultra-short, high-peak-power pulses, operation self-modulated (SM-LWFA) works with more relaxed pulse conditions, albeit at cost of lower beam quality. Modern systems can deliver pulses durations a few tens femtoseconds and peak powers on order terawatts, kHz repetition rates. These are well-suited for developing SM-LWFA applications where high average energy charge prioritized over Such beams could be used to generate...

10.48550/arxiv.2407.20087 preprint EN arXiv (Cornell University) 2024-07-29

Introduction: Quality control is essential to ensure safety and prevent errors in the administration of ionizing radiation across various radiotherapy techniques. Objective: To evaluate performance ArcCheck detector implement a specific quality technique for patients treated with dynamic arc therapy. Methods: Fifty 6 MV 10 energies on Clinac® Varian CX were selected. Doses at isocenter each treatment plan analyzed using polymethyl methacrylate phantom (30 x 30 15 cm³) validate reference...

10.25176/rfmh.v24i4.6793 article EN cc-by Revista de la Facultad de Medicina Humana 2024-10-31

The ever-growing need for radiopharmaceuticals, i.e., compounds containing pharmaceutical drugs and radioisotopes used medical diagnostic imaging (SPECT/PET scan) treating neoplasms, is significantly leading to an increased demand such substances in hospitals clinics worldwide. Currently, most large-scale productions of required radiopharmaceuticals are carried out research reactors, via the fission highly enriched uranium. However, because large amounts radioactive waste produced as...

10.3390/app122412569 article EN cc-by Applied Sciences 2022-12-08

Purpose: To evaluate the response of MAGIC‐f gel through dose curves, percentage depth (PDD) and beam profile for clinical electron beams. Methods: Glass tubes (Vacutainer ®), with 6 cm length 0.5 radius, were positioned inside a water phantom to study doses from Gy 20 in beams 6, 9 e 12 MeV. 1 radius PMMA phantoms 10 × 5 3 used PDD profiles determinations, respectively, maximum 2 gel. The samples analyzed magnetic resonance imaging (MRI) T tomography using head coil, multiple spin echo...

10.1118/1.4735346 article EN Medical Physics 2012-06-01

Photodynamic therapy is a therapeutic modality capable of selectively inducing cytotoxic effects in malignant cells. Such are obtained by using laser or lamp as light source to irradiate previously-delivered photosensitizer into the tumoral Since clinical application photodynamic depends on penetration, lasers and lamps can only be used for shallow tissue treatment. To overcome this limitation, x-ray induced has been recently proposed. The goal work investigate interactions medium containing...

10.15392/bjrs.v9i1.1639 article EN cc-by Brazilian Journal of Radiation Sciences 2021-03-27

The present work compared the relative absorbed dose of some dosimetric materials, for energies 250 kV and 6 MV, using PENELOPE MNCPX codes. composition each material GD-301, TLD-100, MAGIC, MAGAT were simulated disposed in a phantom filled with water following reference conditions recommended by TRS-398 protocol. Percentage depth was used as parameter comparison. Since obtained results both codes found maximum difference up to 2 % when experimental data before 6cm 2.2% MV 5.5 kV. Ratios...

10.15392/bjrs.v10i3.2049 article EN cc-by Brazilian Journal of Radiation Sciences 2022-09-18

Abstract In photodynamic therapy (PDT), a photosensitizing agent is administered following irradiation on the target volume. The wavelength beam to activate photosensitizer ranging from 400 nm 800 nm. Such wavelengths are generated by laser and non-laser light sources. However, use of x-ray induced in has been investigated as combination radiotherapy PDT. Moreover, x-rays used for deeper penetration into tissue, extending this tumours that would not be reachable conventional general, with...

10.1088/1742-6596/1826/1/012052 article EN Journal of Physics Conference Series 2021-03-01

Purpose: Reconstructing the energy spectrum from three linear accelerators (LINACs) using experimental measurements of percentage depth dose curve (PDD). Methods: The experimentally obtained curves were used to solve Fredholm integral equation. photon beam spectra are linked radiation doses through a equation, utilizing optimization method generalized simulated annealing. resulting was employed simulate reference condition as recommended by TRS-398. Monte Carlo codes in this study PENELOPE...

10.2139/ssrn.4583336 preprint EN 2023-01-01

Purpose: To simulate dose distributions around gold‐198 nanoparticles using the Monte Carlo method and study relation between concentration homogeneity in a tissue. Method Materials: with 500 nm of radius immersed water phantom were simulated PENELOPE simulation code. The spatial resolution simulations wasset to 0.32 μm. Gold K‐edge decay (80.7 keV), L1‐edge (14.7 L2‐edge (13.4 keV) L3‐edge (12 energies individually. A volumetric distribution Au particle was obtained percentage depth curves...

10.1118/1.3181441 article EN Medical Physics 2009-06-01

A técnica de Radioterapia Intensidade Modulada (IMRT) utilizada nos tratamentos diversos sítios, exige um controle qualidade (CQ) individual e específico devido à complexidade na entrega da distribuição dose. Para realização CQ em IMRT são utilizados detectores que visam medidas absolutas ou relativas valores dose absorvida. O objetivo do presente trabalho foi promover estudo comparativo dos das distribuições diferentes detectores, com os sistema planejamento (TPS) verificar a influência...

10.29384/rbfm.2018.v12.n1.p16-21 article PT Revista Brasileira de Física Médica 2018-12-13

Objective.The goal of this study was to use Monte Carlo (MC) simulations and measurements investigate the dosimetric suitability an interventional radiology (IR) c-arm fluoroscope deliver low-dose radiotherapy lungs.Approach.A previously-validated MC model IR used calculate dose distributions in a COVID-19-infected patient, 20 non-infected patients varying sizes, postmortem subject. Dose for PA, AP/PA, 3-field 4-field treatments irradiating 95% lungs 0.5 Gy were calculated. An algorithm...

10.1088/2057-1976/ac8939 article EN Biomedical Physics & Engineering Express 2022-08-12
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