A5032210311- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Bladder and Urothelial Cancer Treatments
- Urinary Bladder and Prostate Research
- Pelvic floor disorders treatments
- Lymphoma Diagnosis and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Innovations in Medical Education
- Urologic and reproductive health conditions
- Cancer Immunotherapy and Biomarkers
- Chronic Lymphocytic Leukemia Research
- Diversity and Career in Medicine
- Urinary Tract Infections Management
- Venous Thromboembolism Diagnosis and Management
- Sexual function and dysfunction studies
- Abdominal vascular conditions and treatments
- Urological Disorders and Treatments
- Economic and Financial Impacts of Cancer
- MRI in cancer diagnosis
- Viral-associated cancers and disorders
- Esophageal Cancer Research and Treatment
- Ovarian function and disorders
- Smoking Behavior and Cessation
- Genital Health and Disease
- Testicular diseases and treatments
Kaiser Permanente Walnut Creek Medical Center
2025
Washington University in St. Louis
2021-2023
Franciscan Health
2021-2023
Virginia Mason Medical Center
2019-2022
Seattle University
2019-2022
Hartford Hospital
2015-2020
GTx (United States)
2020
UConn Health
2018
Farmington Community Library
2016-2017
University of Connecticut
2016
Checkpoint inhibitors (CPIs) increase antitumor activity by unblocking regulators of the immune response. This action can provoke a wide range immunologic and inflammatory side effects, some which be fatal. Recent studies suggest that CPI-induced immune-related adverse events (irAEs) may predict survival However, little is known about mechanisms this association. study was undertaken to evaluate influence tumor diagnosis preexisting clinical factors on types irAEs experienced cancer patients...
Conventional prostate magnetic resonance imaging has limited accuracy for clinically significant cancer (csPCa). We performed diffusion basis spectrum (DBSI) prior to biopsy and applied artificial intelligence models these DBSI metrics predict csPCa. Between February 2020 March 2024, 241 patients underwent MRI that included conventional DBSI-specific sequences biopsy. used with DBSI-metrics as input classifiers the pathology ground truth. The DBSI-based model was compared available...
No AccessJournal of UrologyAdult Urology1 May 2018National Comprehensive Cancer Network® Favorable Intermediate Risk Prostate Cancer—Is Active Surveillance Appropriate? Monty A. Aghazadeh, Jason Frankel, Matthew Belanger, Tara McLaughlin, Joseph Tortora, Ilene Staff, and R. Wagner AghazadehMonty Aghazadeh , FrankelJason Frankel BelangerMatthew Belanger McLaughlinTara McLaughlin TortoraJoseph Tortora StaffIlene Staff WagnerJoseph View All Author...
To evaluate the Caprini score as an independent predictor of venous thromboembolism (VTE) in patients undergoing robotic-assisted radical prostatectomy (RARP) and to identify appropriate cut-points for clinical use.We performed a retrospective review who underwent RARP prostate cancer between December 2003 February 2016. VTE cases developed condition within 90 days discharge. The control group was comprised whose most closely preceded followed each case time were matched on lymph node...
387 Background: Treatment of localized prostate cancer (PCa) with surgery or radiotherapy remains suboptimal failure rates 35-40%. Bruton’s Tyrosine Kinase (BTK) is seen elevated in PCa tissues compared to normal tissue. Malignant B-cell density has been correlated higher risk aggressive and mitigating that through the BTK proposed mouse models. Ibrutinib a potent inhibitor which targets signaling pathways, an established safety profile, shown inhibit vivo tumor growth pre-clinically....
You have accessJournal of UrologyProstate Cancer: Localized: Surgical Therapy IV1 Apr 2017MP47-17 CAPRINI SCORE PREDICTS VENOUS THROMBOEMBOLIC EVENTS IN PATIENTS UNDERGOING ROBOTIC ASSISTED PROSTATECTOMY Jason K Frankel MD, Matthew Belanger, Joseph Tortora BA, Tara McLaughlin PhD, Ilene Staff and Wagner MD MDJason , BelangerMatthew Belanger BAJoseph BA PhDTara PhD PhDIlene MDJoseph View All Author Informationhttps://doi.org/10.1016/j.juro.2017.02.1477AboutPDF ToolsAdd to favoritesDownload...
<h3>Background</h3> Treatment of localized prostate cancer with surgery or radiotherapy remains suboptimal failure rates 35–40%.<sup>1</sup> Neoadjuvant androgen deprivation therapy improved pathologic outcomes, but did not significantly impact progression-free overall survival.<sup>2</sup> Prostate higher density B cells correlates stage disease and risk recurrence progression.<sup>3</sup> Elevated levels BTK (Bruton's tyrosine kinase) – an enzyme known to have critical roles in cell...
You have accessJournal of UrologyUrodynamics/Lower Urinary Tract Dysfunction/Female Pelvic Medicine: Non-neurogenic Voiding Dysfunction II1 Apr 2016MP77-06 DETRUSOR HYPERACTIVITY WITH IMPAIRED CONTRACTILITY: URODYNAMIC FINDINGS AND THE NEED FOR MORE PRECISE DEFINITIONS. Jason K Frankel, Andrew C Boylan, and Phillip P Smith FrankelJason Frankel More articles by this author , BoylanAndrew Boylan SmithPhillip View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.1920AboutPDF...
Despite low rates of transfusion associated with robotic prostatectomy, surgeons routinely obtain preoperative blood typing. Here we aim to understand the cost savings eliminating typing prior prostatectomy.A retrospective review our single surgeon radical prostatectomy database was performed. Patients receiving transfusions within 3 days were identified and clinical characteristics recorded. Cost information obtained, descriptive statistical analysis performed.1,581 patients underwent from...
You have accessJournal of UrologyUrodynamics/Lower Urinary Tract Dysfunction/Female Pelvic Medicine: Basic Research & Pathophysiology II1 Apr 2016MP68-09 URODYNAMICS IN UNDERACTIVE BLADDER: ABNORMAL VOLUME MANAGEMENT VS. DETRUSOR DEFICIENCY Gerard Pregenzer, Jason K Frankel, and Phillip Smith PregenzerGerard Pregenzer More articles by this author , FrankelJason Frankel SmithPhillip View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.1346AboutPDF ToolsAdd to favoritesDownload...
Objective: Underactive bladder (UAB) is receiving increased attention as a contributor to urinary bother. An emerging definition of UAB focuses on voiding symptoms suggestive urodynamic detrusor underactivity. However, while animal and tissue studies are useful elucidate pathophysiologic mechanisms, they cannot directly address human symptoms. Objective dysfunctions associated with remain unclear. We therefore sought describe the observations consistent UAB. Methods: A retrospective review...
You have accessJournal of UrologyProstate Cancer: Localized: Active Surveillance III1 Apr 2017PD55-10 ONCOLOGIC OUTCOMES AFTER RADICAL PROSTATECTOMY IN FAVORABLE INTERMEDIATE RISK GROUP ACTIVE SURVEILLANCE CANDIDATES Monty Aghazadeh, Jason K Frankel MD, Matthew Belanger, Tara McLaughlin PhD, Ilene Staff, and Joseph Wagner, MD AghazadehMonty Aghazadeh More articles by this author , MDJason BelangerMatthew Belanger PhDTara PhD PhDIlene MDJoseph View All Author...