- Microfluidic and Capillary Electrophoresis Applications
- Microfluidic and Bio-sensing Technologies
- Electrowetting and Microfluidic Technologies
- Innovative Microfluidic and Catalytic Techniques Innovation
- Analytical Chemistry and Sensors
- Advanced Semiconductor Detectors and Materials
- Semiconductor Quantum Structures and Devices
- Advanced MEMS and NEMS Technologies
- Electrohydrodynamics and Fluid Dynamics
- Nanowire Synthesis and Applications
- Electron and X-Ray Spectroscopy Techniques
- nanoparticles nucleation surface interactions
- Chalcogenide Semiconductor Thin Films
- Nuclear Materials and Properties
- Micro and Nano Robotics
- Gas Sensing Nanomaterials and Sensors
- Advanced Sensor and Energy Harvesting Materials
- Semiconductor materials and devices
- Silicon Nanostructures and Photoluminescence
- 3D Printing in Biomedical Research
- Electrochemical sensors and biosensors
- Advanced biosensing and bioanalysis techniques
- Nanofabrication and Lithography Techniques
- Extracellular vesicles in disease
- Nanopore and Nanochannel Transport Studies
Laboratoire d'Analyse et d'Architecture des Systèmes
2011-2025
Centre National de la Recherche Scientifique
2010-2025
Université de Toulouse
2007-2025
Roche (France)
2002-2016
Université Toulouse III - Paul Sabatier
2008-2016
Roche (Switzerland)
1992-2014
École Centrale de Lyon
2006
Université Paris-Sud
2006
Laboratoire d'Informatique et d'Automatique pour les Systèmes
1991
Laboratoire d'Optique Appliquée
1985-1988
Microfluidics is an emerging field that has given rise to a large number of scientific and technological developments over the last few years. This review reports on use various materials, such as silicon, glass polymers, their related technologies for manufacturing simple microchannels complex systems. It also presents main application fields concerned with different most significant results reported by academic industrial teams. Finally, it demonstrates advantage developing approaches...
The fabrication of three-dimensional (3D) microfluidic networks entirely made SU-8 with integrated electrodes is reported. described technology allows the uncrosslinked dry film on a polyester (PET) sheet and its subsequent lamination to form closed microstructures. Unlike other reported methods, transferred layers are patterned following bonding step allowing more accurate simple alignment between levels than techniques using already layers. Dry release complete polymer microstructure was...
We investigated the interactions between liquid, gas, and solid phases in capillary filling process of closed-end nanochannels. This paper presents theoretical models without with absorption diffusion gas molecules liquid. Capillary experiments were carried out silicon nanochannels different lengths. The measured characteristics length versus time are compared. results show that consists two stages. first stage resembles an open-end nanochannel. However, a remarkable discrepancy experimental...
Mesenchymal stromal cells (MSCs) hold significant promise for their therapeutic potential and possible role as disease biomarkers. While evidence suggests the presence of circulating Adipose-derived MSC (ASC) in peripheral blood (PB), isolating them is particularly challenging due to low abundance, size variability, incomplete characterization native immunophenotype PB. Consequently, relationship between ASC frequency various physiological or pathological conditions has been underexplored....
This work describes how selective patterning of hydrophobic and hydrophilic areas inside microchannels microfluidic devices can be achieved by combining well-known chemical protocols standard photolithography equipment (365 nm). Two techniques have been performed compared. The first technique is based on the preparation self-assembled monolayers photocleavable organosilane second one photoassisted grafting nm) (SAMs) a silicon or glass substrate. In case, we begin with carrying an...
Magnetotactic bacteria (MTB) have the unique capacity to align and swim along geomagnetic field lines downward oxic-anoxic interface in chemically stratified water columns sediments. They are most abundant within first few centimetres of sediments below water-sediment interface. It is unknown how MTB penetrate into sediment layer pocket water, while their movements restricted by alignment magnetic lines. Here we characterized swimming behaviour marine fast-swimming magnetotactic ovoid...
A flexible microfluidic system embedding microelectromagnets has been designed, modeled and fabricated by using a photosensitive resin as structural material. The fabrication process involves the integration of micro-coils in multilayer SU-8 combining standard electroplating dry films lamination. This technique offers numerous advantages terms integration, biocompatibility chemical resistance. Various designs micro-coils, including spiral, square or serpentine wires, have simulated...
We demonstrate the use of a novel dry film photoresist DF-1000 series for fabrication multilevel microfluidic devices by combining standard lithography technique and lamination technology. The optimization technological process enables achievement high aspect ratio structures: 7 : 1 free standing structures 5 channel structures. proved that DF films feature low autofluorescence level, similar to SU-8 resist compatible with most lab-on-a-chip applications. chemical stability against...
We push the limits of hydrodynamic filtration by demonstrating filter-less sorting submicron particles, in line with model and simulations.
Abstract We report on a novel approach for controlling nanohydrodynamic properties at the solid–liquid interfaces through use of stimuli‐responding polymer coatings. The end‐tethered polymers undergo phase separation upon external activation. reversible change in thickness and polarity grafted yields dynamic control surface‐generated, electrokinetic phenomena. Nonactivated, swollen are thicker than electrical double layer (EDL) prohibit development an EOF even charged surfaces. On other...
Abstract While capillary filling in channels of micrometers scale is experimentally verified to obey Washburn's law well, the speed nanochannels noticeably lower than described by formula. This article reports theoretical and experimental results on open-end closed-end nanochannels. Nanochannels 45 nm 80 depth, 10 μm width, were etched silicon bonded a glass cover. Experiments non-electrolytic liquid carried out. The processes observed recorded. To estimate influence electrokinetics,...
This paper presents the first results of fabrication and characterization a biological sensor based on two complementary parts. A microfluidic channel along with micromachined stop-band filter are used to detect type fluid which flows beneath electronic circuit. The tridimensional (3D) structure microstrip technology is integrated using SU8 material thus supports use buried channels. Besides being method without contact, this bio-sensor avoids evaporation, contamination, or label fixation....
Nanofluidics is the science and technology involving a fluid flowing in or around structures with least one dimension nanoscale, which defined as range from 1 nm to 100 nm. In this paper, we present fabrication characterization of nanochannels silicon glass. Since lateral channels limited by wavelength UV light used photolithography, channel width can only be fabricated micrometer scale. However, depth controlled precisely etching rate reactive ion (RIE). Microchannels access holes were...